Genome-wide association analyses of magnetic resonance imaging data describe the genetic architecture of 13 cortical phenotypes at both global and regional levels, implicating neurodevelopmental and constrained genes.
Category: biotech/medical – Page 766
A new method allows large quantities of muscle stem cells to be safely obtained in cell culture. This provides a potential for treating patients with muscle diseases – and for those who would like to eat meat, but don’t want to kill animals.
Elon Musk delves into the groundbreaking potential of Neuralink, a revolutionary venture aimed at interfacing with the human brain to tackle an array of brain-related disorders. Musk envisions a future where Neuralink’s advancements lead to the resolution of conditions like autism, schizophrenia, memory loss, and even spinal cord injuries.
Elon Musk discusses the transformative power of Neuralink, highlighting its role in restoring motor control after spinal cord injuries, revitalizing brain function post-stroke, and combating genetically or trauma-induced brain diseases. Musk’s compelling insights reveal how interfacing with neurons at an intricate level can pave the way for repairing and enhancing brain circuits using cutting-edge technology.
Discover the three-layer framework Musk envisions: the primary layer akin to the limbic system, the more intelligent cortex as the secondary layer, and the potential tertiary layer where digital superintelligence might exist. Musk’s thought-provoking perspective raises optimism about the coexistence of a digital superintelligence with the human brain, fostering a harmonious relationship between these layers of consciousness.
Elon Musk emphasises the urgency of Neuralink’s mission, stressing the importance of developing a human brain interface before the advent of digital superintelligence and the elusive singularity. By doing so, he believes we can mitigate existential risks and ensure a stable future for humanity and consciousness as we navigate the uncharted territories of technological evolution.
For more insights, visit EM360tech.com:
https://em360tech.com/tech-news.
#AI #superintelligence #machinelearning.
A new technique mimics the normal reprogramming process in early embryonic development to essentially wipe a cell’s memory, making it similar to a stem cell.
The dome is varnished matte black and shaped somewhere between an oversized eco-chic lampshade and a fifth grader’s diorama of a volcano—all pudgy curves and asymmetric slopes. Underneath sits a small table, almost a stool, made of the same amorphous material. The table is fitted with a brass fixture loosely reminiscent of a guitar but (so the adjacent panel tells me) is actually a replica of the 17th-century microscope designed by Dutch scientist Antonie van Leeuwenhoek—a nod to the father of microscopy.
From a speaker concealed in the dome, a voice intones:
In the midst of a global pandemic, on the eve of an irreversible climate emergency, and in the early, thrilling decades of a biotech revolution, the human race began to question its relationship to the natural world. For many years, scientists believed life to be a competition, one that humanity must win… But as biologists learned more about living systems, it became undeniable that interdependence was key to understanding life on Earth.
One of the biggest challenges of researching organs in vivo (or as part of an entire, living organism) is that there is little room for error. Finding treatment for a patient’s kidney, intestine, heart, or any organ must be done carefully; if anything goes wrong, it’s the person’s life on the line. Enter the organoid.
First fully realized and developed in the early 2010s, an organoid is a miniaturized and simplified version of an organ produced in vitro (or outside the entire organism: on their own). The organoid has significant use for researchers as it can be grown, researched, then recreated if any treatments cause tissue harm. Isolating the treatments to an in vitro organ gives researchers flexibility; they can focus entirely on targeted treatments without worrying about harming a living patient.
One of the most significant scientific advances of the last ten years, organoids have revolutionized research across several fields, and continue to grow more advanced and helpful year over year. So, what are these microscopic powerhouses, exactly?
Plus a monkey who took a selfie and ignited a years-long legal battle and crow pooping antics, and more weird things we learned this week.
A team of scientists took a bunch of macaque monkeys, made them into alcoholics, and then successfully weaned them off the sauce after injecting their brains with a special gene — an experiment, detailed in a new paper published in Nature Medicine, that could potentially provide a compelling new treatment for addiction.
“Drinking went down to almost zero,” Oregon Health and Science University professor and co-author Kathleen Grant told The Guardian. “For months on end, these animals would choose to drink water and just avoid drinking alcohol altogether.”
The researchers set out with the premise that continued alcohol use causes changes to neurons and hampers the dopamine “reward circuitry” in the brain.
Since this book is about what I consider intellectual subject matter, I think it’s relevant to keep brains in top shape and thought it would be important to share this. You probably know about this sort of thing but I didn’t know the specific nutrients needed and what was lacking in people with Alzheimer’s. Best wishes.
Alzheimer’s disease is a progressive neurodegenerative disease estimated to affect 6 million Americans and 33 million people worldwide. Large numbers of those affected have not yet been diagnosed.
A new study published in the Journal of Alzheimer’s Disease by a Virginia Tech Carilion School of Medicine faculty member shows that brain levels of dietary lutein, zeaxanthin, lycopene, and vitamin E in those with Alzheimer’s disease are half those in normal brains. Higher dietary levels of lutein and zeaxanthin have been strongly linked to better cognitive functions and lower risk for dementia or Alzheimer’s disease.
“This study, for the first time, demonstrates deficits in important dietary antioxidants in Alzheimer’s brains. These results are consistent with large population studies that found risk for Alzheimer’s disease was significantly lower in those who ate diets rich in carotenoids, or had high levels of lutein and zeaxanthin in their blood, or accumulated in their retina as macular pigment,” said C. Kathleen Dorey, professor in the Department of Basic Science Education at the medical school. “Not only that, but we believe eating carotenoid-rich diets will help keep brains in top condition at all ages.”
Testing the efficacy of a vaccine candidate is typically a long process, with the immune response of an animal model taking around two months.
A multi-institution team, led by Matt DeLisa, the William L. Lewis Professor in the Smith School of Chemical Biomolecular Engineering, at Cornell Engineering, is developing a method that is more than an order of magnitude faster.
Using a biomaterials-based organoid, developed in the lab of former Cornell professor Ankur Singh, now at the Woodruff School of Mechanical Engineering at the Georgia Institute of Technology, the team was able to assess the strength of the immune response in just days.