The first generalist medical AI system is out. DeepMind just announced Med-PaLM M, a Multimodal Generative AI model that understands:
Category: biotech/medical – Page 703
The World Health Organization stated it’s possible but based this on limited evidence and no explanation of the mechanism for causing it.
One of the challenges in treating cancer is stopping it from metastasizing, and a new study reveals one of the fundamental mechanisms through which this happens. Now we know about this mechanism, perhaps we can stop it.
Key to this newly discovered process is GRP78, and it’s what’s known as a chaperone protein. It’s a type of protein that lends a hand in the folding or unfolding of larger proteins, basically building them up (or tearing them down), which then affects whether they’re biologically active and functional.
A team led by the Keck School of Medicine at the University of Southern California (USC) in the US found that cancer cells can hijack GRP78, using the protein to spread further in the body and resist treatment.
In a recent study published in PLoS ONE, researchers examine a wide range of lifestyle variables in the context of multimorbidity of chronic non-communicable illnesses.
Study: Lifestyle factors related to prevalent chronic disease multimorbidity: A population-based cross-sectional study. Image Credit: Amorn Suriyan / Shutterstock.com.
Aging process slows when older mice share circulatory system of young; the longer the animals shared circulatory systems, the more durable the benefits.
Researchers from the Tokyo University of Science recently published a study in the journal Artificial Life and Robotics where they explored how machine learning can help detect deception.
Machine learning is a subset of artificial intelligence (AI) that involves the use of algorithms and statistical models to enable computers to learn and improve from experience without being explicitly programmed. In other words, it is a method of teaching computers to perform specific tasks by learning from data, patterns, and examples, rather than relying on pre-defined rules.
Detecting deception can be important in various situations, like questioning crime victims or suspects and interviewing patients with mental health issues. Sometimes, human interviewers might struggle to ask the right questions or spot deception accurately.
Consuming strawberries daily may help improve cognitive function, lower blood pressure, and increase antioxidant capacity, a clinical trial shows.
Reactive oxygen species (ROS) are important in regulating normal cellular processes whereas deregulated ROS leads to the development of a diseased state in humans including cancers. Several studies have been found to be marked with increased ROS production which activates pro-tumorigenic signaling, enhances cell survival and proliferation and drives DNA damage and genetic instability. However, higher ROS levels have been found to promote anti-tumorigenic signaling by initiating oxidative stress-induced tumor cell death. Tumor cells develop a mechanism where they adjust to the high ROS by expressing elevated levels of antioxidant proteins to detoxify them while maintaining pro-tumorigenic signaling and resistance to apoptosis.
A routine osteoporosis screening bone density test can also detect increased risk for a heart attack because of the presence of calcium in the aorta. But reading these images requires expertise and can be time-consuming.
Now, research from a multi-institution collaboration, including Harvard Medical School and Hebrew SeniorLife, reports that this calcification test score can be calculated quickly by using machine learning, without the need for a person to grade the scans.
It’s estimated that as many as one-third of Americans suffer from chronic pain, and many medications that have been developed to treat pain pose serious risks. Scientists have now created a gene therapy that can manipulate a specific channel that sodium ions move through, called NaV1.7. In tests using cells in culture and animal models, this approach successfully relieved chronic pain. The work has been reported in the Proceedings of the National Academy of Sciences (PNAS).
“Our study represents a major step forward in understanding the underlying biology of the NaV1.7 sodium ion channel, which can be harnessed to provide relief from chronic pain,” said senior study author Rajesh Khanna, director of the NYU Pain Research Center and professor of molecular pathobiology at NYU Dentistry.