Lifeboat Foundation

The team, led by Professor Magdalena Zernicka-Goetz, developed the embryo model without eggs or sperm, and instead used stem cells – the body’s master cells, which can develop into almost any cell type in the body.

The researchers mimicked natural processes in the lab by guiding the three types of stem cells found in early mammalian development to the point where they start interacting. By inducing the expression of a particular set of genes and establishing a unique environment for their interactions, the researchers were able to get the stem cells to ‘talk’ to each other.

Researchers have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body.

TOPEKA, Kan. (KSNT) — Multiple packages of frozen fruit, specifically strawberries, are being recalled due to possible Hepatitis A contamination.

The Food and Drug Administration said Willamette Valley Fruit Co. of Salem, Oregon, is voluntarily recalling select packages of frozen strawberries and a frozen fruit blend containing strawberries. The impacted strawberries were grown in Mexico and are potentially carrying Hepatitis A.

Hepatitis A is a contagious liver disease caused by the Hepatitis A virus, which can be spread through close contact with someone who is infected, or by eating foods or consuming beverages that have been contaminated, according to the CDC.

Type 2 diabetes is a significant global health concern, affecting millions of individuals worldwide. The disease is associated with numerous complications, as well as an increased risk of premature mortality. Recent research conducted by the University of Sydney has shed light on the potential of physical activity in preventing the onset of type 2 diabetes, even in individuals with a high genetic risk for the disease [1]. This study underscores the importance of exercise as a key strategy for chronic disease prevention and offers promising news for individuals seeking to reduce their risk of developing type 2 diabetes.

Longevity. Technology: The worldwide burden of type 2 diabetes is substantial, and the disease carries significant implications for public health. Type 2 diabetes is associated with various complications, including cardiovascular diseases, kidney problems and nerve damage. Moreover, individuals with type 2 diabetes often experience a shortened lifespan and reduced healthspan due to the increased risk of developing other chronic conditions. The study’s findings add to the clarion call for effective prevention strategies that alleviate this burden on individuals, families and healthcare systems worldwide.

The research, published in the British Journal of Sports Medicine, involved 59,325 adults enrolled in the UK Biobank project. Participants wore accelerometers on their wrists to measure their physical activity levels and the researchers also considered genetic markers associated with a higher risk of type 2 diabetes. The study followed the participants for up to seven years to assess their health outcomes.

Summary: Researchers developed one of the most comprehensive 3D models of the synapse, the neuron juncture crucial for intercellular communication. This breakthrough allows an unprecedented view of the complex interactions between individual cells at the synapse, offering fresh insights into neurodegenerative diseases such as Huntington’s disease and schizophrenia.

The team used this novel approach to compare healthy mice brains to those with the Huntington’s mutant gene, revealing structural flaws potentially disrupting cellular communication. The researchers believe this technique could significantly advance our understanding of various neurodegenerative and neuropsychiatric diseases.

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Continue reading “Vitamin B6 Didn’t Impact NAD (Test Results)” »

As people get older, they tend to have lower levels of anxiety. But why? A new brain imaging study has found that older individuals are faster at recognizing and responding to negative emotions. The findings, published NeuroImage, go against the idea that older adults are less engaged with negative emotions due to cognitive decline or that they are better at regulating negative emotions. Instead, the results suggest that older adults may develop a more automatic way of processing negative emotions.

The study aimed to investigate the relationship between aging, trait anxiety, and changes in cognitive and affective functions. The researchers were motivated by previous findings that older adults tend to have lower susceptibility to anxiety disorders compared to younger and middle-aged adults. However, it was not clear how age-related changes in anxiety symptoms, such as worry and somatic symptoms, were related to changes in cognitive and affective processes.

“We are interested in emotion dysfunction in early dementia, including those people with subjective complaints of memory problem and mild cognitive impairment,” said study author Chiang-shan Ray Li, a professor of psychiatry and neuroscience at Yale University School of Medicine.

In my new Newsweek Op-Ed, I tackle a primary issue many people have with trying to stop aging and death via science. Hopefully this philosophical argument will allow more resources & support into the life extension field:

Philosophers often say if humans didn’t die, we’d be bored out of our minds. This idea, called temporal scarcity, argues the finitude of death is what makes life worth living. Transhumanists, whose most urgent goal is to use science to overcome biological death, emphatically disagree.

For decades, the question of temporal scarcity has been debated and analyzed in essays and books. But an original idea transhumanists are putting forth is reinvigorating the debate. It doesn’t discount temporal scarcity in biological humans; it discounts it in what humans will likely become in the future—cyborgs and digitized consciousnesses.

Continue reading “Eliminating Death Doesn’t Mean Life Will Get Boring” »

The research is a result of observations from awake language mapping during brain tumor surgery.

A team of Chinese researchers has developed a way to artificially produce speech, also known as speech synthesis, using cues from neural brain activity.

According to the South China Morning Post, the researchers claim that they have a mind-reading machine that is capable of turning human thought into spoken Mandarin.

Summary: Researchers discovered a unique property of psychedelic drugs: their ability to reopen “critical periods” in the brain, times when the brain is highly susceptible to environmental learning signals. These periods, usually associated with skills development like language learning, are reopened by psychedelics for different lengths of time.

This breakthrough in understanding psychedelic drug function may have therapeutic implications for conditions like stroke and deafness. Further, it uncovers novel molecular mechanisms influenced by psychedelics.