Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 533

In the realm of scientific innovation, the past decade has seen the CRISPR/Cas systems emerge as a groundbreaking tool in genome editing, boasting applications that span from enhancing crop yields to pioneering gene therapy.

The recent advent of CRISPR-COPIES by the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) marks a significant leap forward, refining CRISPR’s flexibility and user-friendliness.

CRISPR-COPIES represents a cutting-edge solution designed to swiftly pinpoint ideal chromosomal sites for genetic modification across any species.

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Scientists at the University of Wisconsin–Madison (UWM) say they have created the first 3D-printed brain organoids that function like natural brain tissue.

“The neurons communicate, send signals, interact with each other through neurotransmitters, and even form proper networks with support cells that were added to the printed tissue,” said senior author Su-Chun Zhang.

The challenge: In the right conditions, stem cells will self-assemble into tiny, three-dimensional tissues that mimic features of the human brain. These “brain organoids” can be used to test drugs, study diseases, and more.

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Plasminogen deficiency, a rare disorder characterized by impaired fibrinolysis, frequently results in ligneous conjunctivitis. In this report, we report a case of a Saudi girl manifesting both conjunctivitis and hydrocephalus. Her initial symptoms at 1 month of age were recurring eye redness, which was inaccurately diagnosed as simple conjunctivitis. Surgical intervention for her ocular lesions revealed underlying membrane deposition. She later exhibited signs of increased intracranial pressure, resulting in a hydrocephalus diagnosis and subsequent surgery. Genetic analysis confirmed the presence of plasminogen deficiency. Clinical evaluations highlighted ligneous conjunctivitis, variations in visual acuity, and facial acne. Laboratory assessments demonstrated diminished plasminogen levels.

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An air traffic controller’s routine can be disrupted by an aircraft that requires special handling. This could range from an emergency to priority handling of medical flights or Air Force One. Controllers are given the responsibility and the flexibility to adapt how they manage their airspace.

The requirements for the front line of air traffic control are a poor match for AI’s capabilities. People expect air traffic to continue to be the safest complex, high-technology system ever. It achieves this standard by adhering to procedures when practical, which is something AI can do, and by adapting and exercising good judgment whenever something unplanned occurs or a new operation is implemented – a notable weakness of today’s AI.

Indeed, it is when conditions are the worst – when controllers figure out how to handle aircraft with severe problems, airport crises or widespread airspace closures due to security concerns or infrastructure failures – that controllers’ contributions to safety are the greatest.

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Benjamin Franklin famously wrote: “In this world nothing can be said to be certain, except death and taxes.” While that may still be true, there’s a controversy simmering today about one of the ways doctors declare people to be dead.

Bioethicists, doctors and lawyers are weighing whether to redefine how someone should be declared dead. A change in criteria for brain death could have wide-ranging implications for patients’ care.

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A case of the bubonic plague has hit Oregon, and the likely cause was a cat.

Health officials in Deschutes County announced last week that a resident, who has not been identified, had been diagnosed with the plague, in the state’s first human case in eight years. The individual was likely infected by their cat, the department says.

“All close contacts of the resident and their pet have been contacted and provided medication to prevent illness,” said Dr. Richard Fawcett, the Deschutes County Health Services Officer.

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There are many pain points that warrant discussions between the two nations but AI could be the thing that brings them to the table.

Relations between the United States and China have been downward recently. Topics like artificial intelligence (AI) and such technology in automated weapons could be common points of interest to get the two countries talking again.

Tensions between the two nations have been on the rise for a host of issues. Recently, the origins of the COVID-19 pandemic, China’s burgeoning presence in the South China Sea, and the supply of powerful chips in the technology space have been areas of disagreement on both sides.

The lack of dialogue on such issues has led to tensions between the two countries, and the imposition of restrictions on both sides has further strained relations. While addressing these points is expected to be a long-drawn affair for the two countries, common areas like AI could offer a starting point, experts told the South China Morning Post (SCMP).

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New research on the continuity illusion uncovers how the brain perceives smooth motion, emphasizing the superior colliculus’s importance and suggesting new approaches for neuroscience research and clinical practice.

A study by a team at the Champalimaud Foundation (CF) has cast a new light on the superior colliculus (SC), a deep-seated brain structure often overshadowed by its more prominent cortical neighbor. Their discovery uncovers how the SC may play a pivotal role in how animals see the world in motion, and sheds light on the “continuity illusion,” an essential perceptual process integral to many of our daily activities, from driving vehicles to watching movies.

Understanding the Continuity Illusion.

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Sensors that monitor infrastructure, such as bridges or buildings, or are used in medical devices, such as prostheses for the deaf, require a constant supply of power. The energy for this usually comes from batteries, which are replaced as soon as they are empty. This creates a huge waste problem. An EU study forecasts that in 2025, 78 million batteries will end up in the rubbish every day.

A new type of mechanical sensor, developed by researchers led by Marc Serra-Garcia and ETH geophysics professor Johan Robertsson, could now provide a remedy. Its creators have already applied for a patent for their invention and have now presented the principle in the journal Advanced Functional Materials.

Certain sound waves cause the sensor to vibrate “The sensor works purely mechanically and doesn’t require an external energy source. It simply utilizes the vibrational energy contained in sound waves,” Robertsson says.

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