Lifeboat Foundation

The bioactivity of most near-infrared II (NIRII) fluorophores are limited, thereby conflicting the achievement of strong fluorescence and high catalytic activities, due to a lack of free electrons in the method.

To overcome this challenge, Huizhen Ma and a research team in translational medicine, neural engineering, physics, and materials at the Tianjin University China developed atomically precise gold clusters with strong near-infrared II fluorescence to show potent enzyme-mimetic activities by using atomic engineering, to form active copper single-atom sites.

These gold-copper clusters (Au₂₁ Cu₁) showed higher antioxidant nature with a 90-fold catalase-like and 3-fold higher superoxide dismutase-like activity compared to gold clusters alone. These clusters can be cleared through the kidney to monitor cisplatin-induced renal injury within a 20–120-minute window to visualize the process in 3D via near-infrared light-sheet microscopy.

The successful transfer of a gene that produces HMW-HA paves the way for improving the health and lifespan of humans, too. In a groundbreaking endeavor, scientists at the University of Rochester have successfully transferred a longevity gene from naked mole rats to mice, leading to enhanced health and increased lifespan. Naked mole rats, noted for their resistance to age-related diseases, have a gene that produces high molecular weight hyaluronic acid (HMW-HA), which when introduced to mice, demonstrated potential anti-aging benefits.

The battery can be charged for up to 200 cycles and does not contain wires or toxic heavy metals.

Researchers at the Nanyang Technological University (NTU) in Singapore have devised a micrometer-thin battery that can power smart contact lenses and be charged with tears, a university press release said.

Continue reading “Smart contact lens battery charged by human tears” »

Ever since the Jerry Lewis telethons began in the 1960s, millions of people have become familiar with an otherwise rare disease called muscular dystrophy (MD).

The medical world has learned much over the ensuing years, including that more than 30 closely related disorders exist that can produce the gradual muscle degeneration that steals a child’s ability to walk and eventually disrupts other organ functions. An estimated 250,000 people in the U.S. are living with a muscular dystrophy. While many are living longer lives thanks to improved treatments, no cure has been found.

Now an eye-opening study led by scientists at Cincinnati Children’s—published Aug. 25, 2023, in Science Advances —reports an entirely new approach to preventing the muscle-wasting symptoms of MD. The research focuses on the role played by mitochondria, the tiny organelle within our cells that processes nutrients into the energy cells need to survive.

So past the 7 minute mark we see a competing interest may have stumbled upon the same thing so Katcher and gang are starting a company to commercialize E5.

Here we review a preprint from Dr Katcher and Dr Horvath giving more detail on the experiments which showed a 54% epigenetic rejuvenation in rats and reveals the source of E5 and the processing involved.

Continue reading “The Identity Of E5 Revealed | Reduced Epigenetic Age By More Than 50%” »

Get my new Longevity Practices book for free: https://www.diamandis.com/longevity.

In this episode, filmed during Abundance360, Peter and David discuss David’s groundbreaking research on reversing aging through epigenetic changes, emphasizing that aging is not just damage to the body but a loss of information. They talk about age reversal as a possibility, rejuvenating brains, and regaining lost memories.

Continue reading “Aging is Now Optional w/ David Sinclair | EP #60” »

Goldbeating, an age-old craft pioneered by ancient Egyptian artisans more than five millennia ago, involves the meticulous thinning of bulk gold into gossamer-like leaves. Throughout history, this intricate process has adorned various masterpieces, such as the tombs of Thebes and Saqqara, and has cemented its place in art and adornments across cultures. Today, nanoscale gold is used not only for decorating fancy desserts, but is indispensable for modern applications ranging from microelectronics to nanomedicine.

Human Immortality — If you thought Human Immortality was just a concept in science fiction, this episode reveals how it will become science fact. For some scientists featured in this program, achieving Immortality is not a question of ‘If’. The real question is ‘When?’.

Human Immortality (2022)
Director: Emma Watts.
Writers: Kyle McCabe, Christopher Webb Young.
Stars: Samantha Brady, Aubrey DeGrey, Leonard Guarente.
Genre: Documentary.
Country: United States.
Language: English.
Release Date: August 31, 2022 (United States)

Continue reading “Human Immortality | Life Extension | Advancements in Science” »

A study claims that the quality of AI-generated responses to patient eye care questions is comparable to that of certified ophthalmologists.