A new gene editing technique derived from bacterial “jumping genes” can add, remove, recombine and invert DNA sequences, potentially overcoming some of the limitations of CRISPR.
The approach is made possible by a molecule called bridge RNA, the discovery of which came about through a joint effort led by scientists at the Arc Institute in Palo Alto, California, in collaboration with the University of Tokyo. They described their work in a pair of papers published June 26 in Nature.
As part of the 2024 Prostate Cancer Patient Conference, Dr. Eric Small discusses systemic therapy treatment in advanced prostate cancer, including AR-targeted therapy. The presentation includes definitions of disease states, categories of treatment types, and standards in treatment selection.
Recorded on 03/09/2024. [Show ID: 39768]
Donate to UCTV to support informative \& inspiring programming:
https://www.uctv.tv/donate.
Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date.
More videos from: Prostate Cancer Patient Conference.
(https://www.uctv.tv/prostate-cancer-c…)
Explore More Health \& Medicine on UCTV
(https://www.uctv.tv/health)
UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more.
UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California — teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world.
So, they get very healthy but only live 24% longer no matter how many more times they use the treatment. I wonder what the telomere effect is. And what they are doing is not the same as what Aubrey’s mouse experiment is doing.
Altos Labs Co-founder and Chief Scientist Rick Klausner participated in a panel discussing efforts to increase human healthspan by combatting age-related diseases at this year’s Aspen Ideas Health conference.
In a panel that included Laura Deming and Kristen Fortney, Klausner discussed an Altos experiment in Spain (likely to be research conducted by Universidad Católica de Murcia and Altos Labs in collaboration with the Hospital Clínic de Barcelona), Klausner reported that if old kidneys are transplanted into young people they do not function nearly as well as transplanting young kidneys – but organ donations donors are getting older and older, and therein lies the rub.
We’ve been doing these experiments with the transplant team at Barcelona where we remove a kidney from different animals, and now we’re preparing to do this in the clinic. You take an old kidney and you transplant it into a young rat versus [transplanting] a young kidney and you see a tremendous difference in overall survival and kidney function. But when we take the old rat organ and we introduce these components that rejuvenate, this reprogramming cocktail, just for 45 minutes they’re exposed to it and then they survive as well if not better than the young organs that are transplanted.
Only two women from Canada have been to space previously, though Jenni Gibbons will join their ranks in the near future.
Pandya’s first flight to space will be on a commercial mission, which is different from the missions with NASA.
Xylitol is a common zero-calorie sweetener found in sugar-free candy and toothpaste. Cleveland Clinic researchers found higher amounts of the sugar alcohol xylitol are associated with increased risk of cardiovascular events like heart attack and stroke.
The team, led by Stanley Hazen, M.D., Ph.D., confirmed the association in a large-scale patient analysis, preclinical research models and a clinical intervention study. Findings were published today in the European Heart Journal.
Xylitol is a common sugar substitute used in sugar-free candy, gums, baked goods and oral products like toothpaste. Over the past decade, the use of sugar substitutes, including sugar alcohols and artificial sweeteners, has increased significantly in processed foods that are promoted as healthy alternatives.
Chinese researchers have developed an open-source “brain-on-chip” interface system, which is the first of its kind in the world. The system can instruct a robot to avoid obstacles, track, and grasp through “mind control,” the Science and Technology Daily reported on Wednesday.
The interface system was co-developed by research teams from Tianjin University and Southern University of Science and Technology.
The system uses an artificial brain cultivated in vitro – such as a “brain-like organ,” which can interact with external information through encoding, decoding and stimulus-feedback when coupled with electrode chips, according to the report.
The brain is the most complex organ ever created. Its functions are supported by a network of tens of billions of densely packed neurons, with trillions of connections exchanging information and performing calculations. Trying to understand the complexity of the brain can be dizzying. Nevertheless, if we ever hope to understand how the brain works, we need to be able to map neurons and study how they are wired.
Now, publishing in Nature Communications, researchers from Kyushu University have developed a new AI tool, which they call QDyeFinder, that can automatically identify and reconstruct individual neurons from images of the mouse brain. The process involves tagging neurons with a super-multicolor labeling protocol, and then letting the AI automatically identify the neuron’s structure by matching similar color combinations.
Microbes that are used for health, agricultural, or other applications need to be able to withstand extreme conditions, and ideally the manufacturing processes used to make tablets for long-term storage. MIT researchers have now developed a new way to make microbes hardy enough to withstand these extreme conditions.
Their method involves mixing bacteria with food and drug additives from a list of compounds that the FDA classifies as “generally regarded as safe.” The researchers identified formulations that help to stabilize several different types of microbes, including yeast and bacteria, and they showed that these formulations could withstand high temperatures, radiation, and industrial processing that can damage unprotected microbes.
In an even more extreme test, some of the microbes recently returned from a trip to the International Space Station, coordinated by Space Center Houston Manager of Science and Research Phyllis Friello, and the researchers are now analyzing how well the microbes were able to withstand those conditions.
This is a recording of the AGI23 Conference, Day 1, June 16th 2023, Stockholm. This video shows the following tutorial: Test and Evaluation First Principles for General Learning Systems, led by Tyler Cody.
SingularityNET was founded by Dr. Ben Goertzel with the mission of creating a decentralized, democratic, inclusive, and beneficial Artificial General Intelligence (AGI). An AGI is not dependent on any central entity, is open to anyone, and is not restricted to the narrow goals of a single corporation or even a single country.
The SingularityNET team includes seasoned engineers, scientists, researchers, entrepreneurs, and marketers. Our core platform and AI teams are further complemented by specialized teams devoted to application areas such as finance, robotics, biomedical AI, media, arts, and entertainment.
Website: https://singularitynet.io.
X: https://x.com/SingularityNET
Instagram: / singularitynet.io.
Discord: / discord.
Forum: https://community.singularitynet.io.
Telegram: https://t.me/singularitynet.
WhatsApp: https://whatsapp.com/channel/0029VaM8…
Warpcast: https://warpcast.com/singularitynet.
Mindplex Social: https://social.mindplex.ai/@Singulari…
Github: https://github.com/singnet.
Linkedin: / singularitynet.
