Lifeboat Foundation

Summary: Researchers made a breakthrough in memory research by genetically modifying the LIMK1 protein, crucial for memory, to be controlled by the drug rapamycin.

This study demonstrates the ability to enhance memory functions by manipulating synaptic plasticity in the brain.

The engineered protein showed significant memory improvement in animal models with age-related cognitive decline, offering potential for innovative treatments for neuropsychiatric diseases like dementia. This ‘chemogenetic’ approach, blending genetics and chemistry, opens new avenues in neurological research and therapy.

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Continue reading “Slow Wave Sleep % Loss Is Associated With An Increased Dementia Risk” »

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed “prognostic modules,” that significantly influence the progression of 32 different types of cancer. The study, published in Genome Research, serves as a comprehensive resource and lays the foundation for the development of next-generation cancer treatments and diagnostic markers.

Despite significant progress in cancer research, understanding the disease’s genetic intricacies remains challenging. Previous research often focused on isolated gene functions in specific cancer types.

We aimed to fill this knowledge gap by providing a comprehensive analysis of gene-gene interactions across various forms of cancer.

In an exclusive interview, Peter Hegemann said AI is more dangerous than optogenetics.

Contrary to popular belief, there is very little chance that optogenetics will be used in the future to control the human brain, says Peter Hegemann, a biochemist and biophysicist, in a conversation with Interesting Engineering (IE) at the Hong Kong Laureate Forum 2023.

Optogenetics is a scientific technique that uses light to control and manipulate cells within living tissues, particularly in the brain. It allows researchers to control the activity of specific neurons with high precision, both in terms of location and timing.

Continue reading “Scientists debunk notions of optogenetics controlling the human brain” »

Get a blood test, check blood pressure, and swab for aliments — all without a doctor or nurse.

Adrian Aoun, CEO and co-founder of Forward Health, aims to scale healthcare.

Adrian Aoun, CEO and co-founder of Forward Health, aims to scale healthcare. It started in 2017 with the launch of tech-forward doctor’s offices that eschewed traditional medical staffing for technology solutions like body scanners, smart sensors, and algorithms that can diagnose ailments. Now, in 2023, he’s still on the same mission and rolled up all the learnings and technology found in the doctor’s office into a self-contained, standalone medical station called the CarePod.

Continue reading “Forward Health launches CarePods, a self-contained, AI-powered doctor’s office” »

Annual low-dose CT lung cancer screening is recommended based on age and smoking history. Find out if you are eligible.

Read about how to use antibiotics and about when not to use antibiotics.

How did life begin? How did chemical reactions on the early Earth create complex, self-replicating structures that developed into living things as we know them?

According to one school of thought, before the current era of DNA-based life, there was a kind of molecule called RNA (or ribonucleic acid). RNA – which is still a crucial component of life today – can replicate itself and catalyse other chemical reactions.

But RNA molecules themselves are made from smaller components called ribonucleotides. How would these building blocks have formed on the early Earth, and then combined into RNA?

New materials developed at the University of Surrey could pave the way for a new generation of flexible X-ray detectors, with potential applications ranging from cancer treatment to better airport scanners.

Traditionally, X-ray detectors are made of heavy, rigid material such as silicon or germanium. New, flexible detectors are cheaper and can be shaped around the objects that need to be scanned, improving accuracy when screening patients and reducing risk when imaging tumors and administering radiotherapy.

Dr. Prabodhi Nanayakkara, who led the research at the University of Surrey, said, “This new material is flexible, low-cost, and sensitive. But what’s exciting is that this material is tissue equivalent. This paves the way for live dosimetry, which just isn’t possible with current technology.”