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Category: biotech/medical – Page 327

For first time, DNA tech stores, rewrites data and even solves sudoku

Forget conventional electronics, DNA tech stores data, offers computing functions.

Called “primordial DNA store and compute engine,” the technology could store data securely for thousands of years in commercially available spaces without degrading the information-storing DNA, suggests testing.

In conventional computing technologies, the ways data are stored and processed are compatible with each other, according to researchers. However, in reality, data storage and data processing are done in separate parts of the computer, and modern computers are a network of complex technologies.

The new technology is made possible by using recent developments, which have enabled the creation of soft polymer materials that have unique morphologies.

Efferocytosis: The Janus‐Faced Gatekeeper of Aging and Tumor Fate

The multistep process by which phagocytes engulf these deceased cells without eliciting an inflammatory response is called efferocytosis. Despite significant insights into the fundamental mechanisms of efferocytosis, its implications in disorders such as aging and cancer remain elusive. Upon summarizing and analyzing existing studies on efferocytosis, it becomes evident that efferocytosis is our friend in resolving inflammation, yet it transforms into our foe by facilitating tumor development and metastasis. This review illuminates recent discoveries regarding the emerging mechanisms of efferocytosis in clearing apoptotic cells, explores its connections with aging, examines its influence on tumor development and metastasis, and identifies the regulatory factors of efferocytosis within the tumor microenvironment. A comprehensive understanding of these efferocytosis facets offers insights into crucial physiological and pathophysiological processes, paving the way for innovative therapeutic approaches to combat aging and cancer.

Diet, Supplements That Correspond To A 17y Younger Biological Age (Test #8 In 2024)

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A Key Brain Difference Linked to Autism Is Found for the First Time in Living People

A key brain difference linked to autism has been found for the first time in living people.

Using a sophisticated imaging technology, Yale School of Medicine researchers found that the brains of autistic adults have fewer synapses — crucial junctions between nerve cells and other cells — than the brains of neurotypical individuals: bit.ly/3NK9gGQ Yale.

Autistic brains have fewer synapses compared to neurotypical brains, PET scans show.

New Insight into Genetic Disease Variability

Summary: New research reveals that certain cells inactivate one parent’s copy of a gene, leading to a bias in gene activity that may explain why some individuals with disease-causing mutations remain symptom-free. This selective gene inactivation, known as monoallelic expression, affects about 1 in 20 genes and varies between cell types.

The study shows that in families with genetic disorders, the active copy of a gene often determines disease severity. These findings challenge traditional genetic paradigms and suggest new approaches to diagnosing and treating inherited diseases.

Surgeon catches cancer from patient in ‘first-ever’ case with experts shocked

In a shocking turn of events, a surgeon operating on a cancer patient managed to contract the deadly disease in what is believed to be an unprecedented case. The doctor was performing surgery on a 32-year-old German man suffering from a rare type of cancer when he accidentally “transplanted” the disease into himself.

This occurred when cells from the patient’s tumor seeped into a cut on the surgeon’s hand. Despite immediate disinfection and bandaging, the 53-year-old medic noticed a hard lump developing at the base of his middle finger five months later.

A hand specialist identified the lump as a malignant tumor genetically identical to cancer suffered by his former patient. Doctors treating him concluded that he had contracted cancer when his patient’s tumor cells seeped into the cut.

Some doctors increasingly using artificial intelligence to take notes during appointments

It was easy to miss Dr. Robert Gray’s quick movements, tapping the screen of his smartphone at the beginning and end of patient visits on a recent day.

But Gray said those fast finger taps have changed his life. He was tapping an app that records discussions during his appointments and then uses to find the relevant information, summarize it and zap it, within seconds, into each patient’s electronic medical record.

The technology was meticulously documenting each visit so Gray didn’t have to.

Timely TGFβ signalling inhibition induces notochord

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The work, published today in Nature, marks a significant step forward in our ability to study how the human body takes shape during early development.

The notochord, a rod-shaped tissue, is a crucial part of the scaffold of the developing body. It is a defining feature of all animals with backbones and plays a critical role in organising the tissue in the developing embryo.

Despite its importance, the complexity of the structure has meant it has been missing in previous lab-grown models of human trunk development.

In this research, the scientists first analysed chicken embryos to understand exactly how the notochord forms naturally. By comparing this with existing published information from mouse and monkey embryos, they established the timing and sequence of the molecular signals needed to create notochord tissue.

With this blueprint, they produced a precise sequence of chemical signals and used this to coax human stem cells into forming a notochord.

The stem cells formed a miniature ‘trunk-like’ structure, which spontaneously elongated to 1–2 millimetres in length. It contained developing neural tissue and bone stem cells, arranged in a pattern that mirrors development in human embryos. This suggested that the notochord was encouraging cells to become the right type of tissue at the right place at the right time.

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