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Category: biotech/medical – Page 320

Pupil Wizard: an app to enhance knowledge of pupillary abnormalities

As neuro-ophthalmology educators, we have sought ways to improve the teaching of pupil-related disorder, focusing on incorporating their dynamic aspects and active learning. Our solution is an app for smartphone and tablet devices. The app, Pupil Wizard, provides a digital textbook featuring a dynamic presentation of the key pupillary abnormalities. It allows the users to interact with a digital patient and explore how each condition responds to direct and indirect light stimuli, near focus, and changes in ambient light (Fig. 1). Moreover, the users can test their knowledge in quiz mode, where random pupillary abnormalities must be correctly identified and multiple-choice questions about them answered.

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To Study Cancer “Kill Switch,” UC San Diego Scientists Will Send Stem Cells to Space

A new cancer treatment discovered by the University of California San Diego Sanford Stem Cell Institute (SSCI) and developed by Aspera Biomedicines will undergo testing in outer space this spring — this as researchers prepare to launch a clinical trial of the drug on Earth.

Rebecsinib, an investigational cancer drug slated to begin a Phase 1 clinical trial this year for patients with high-risk myelofibrosis or secondary acute myeloid leukemia, will be tested aboard the International Space Station (ISS) on four of the deadliest cancer types: ovarian cancer, metastatic breast cancer, acute myeloid leukemia and glioblastoma multiforme.

June 12, 2025

Rebecsinib, a new cancer treatment discovered by UC San Diego Sanford Stem Cell Institute will undergo testing in outer space on an additional four of the deadliest cancer types: ovarian cancer, metastatic breast cancer, acute myeloid leukemia and glioblastoma multiforme.

Low Uric Acid Is Associated With A Higher Odds Of Living To 100y

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Stress genes clear dead cells, offering new disease insights

A new study from The University of Texas at Arlington details a novel strategy for how the body clears out dead cells during stress, revealing unexpected roles for well-known stress-response genes—a discovery that could help scientists better understand diseases affecting the immune system, brain and metabolism.

“The body is constantly creating new cells and removing old cells once they die,” said Aladin Elkhalil, lead author of the study and a third-year doctoral student in the lab of Piya Ghose, assistant professor of biology at UT Arlington. “This removal of is just as important as creating new ones, because if the body is unable to rid itself of dead cells, it can lead to various health problems”

Published in PLOS Genetics, the study was conducted on the roundworm C. elegans by Dr. Ghose, Elkhalil and Alec Whited, another graduate student in the Ghose lab. This tiny, transparent organism is a widely used tool in because its see-through body allows scientists to observe live cell behavior, including how cells die. The research team took advantage of these unique features in several innovative ways.

HKUST Scientists Achieve Breakthrough in Light Manipulation Using Gyromagnetic Zero-Index Metamaterials

The Hong Kong University of Science and Technology (HKUST)-led research team has adopted gyromagnetic double-zero-index metamaterials (GDZIMs) — a new optical extreme-parameter material – and developed a groundbreaking method to control light using GDZIMs. This discovery could revolutionize fields like optical communications, biomedical imaging, and nanotechnology, enabling advances in integrated photonic chips, high-fidelity optical communication, and quantum light sources.

Published in Nature, the study was co-led by Prof. CHAN Che-Ting, Interim Director of the HKUST Jockey Club Institute for Advanced Study and Chair Professor in the Department of Physics, and Dr. ZHANG Ruoyang, Visiting Scholar in the Department of Physics at HKUST.

Neighborly help in the brain: Cerebral cortex networks rapidly reorganize to compensate for lost neurons

How the brain largely maintains its function when neurons are lost—this is what researchers at the University Medical Center Mainz, the Frankfurt Institute for Advanced Studies (FIAS) and Hebrew University (Jerusalem) have deciphered. They show that neuronal networks in the cerebral cortex reorganize within a short period of time, with other nerve cells taking over the tasks of the lost neurons.

These findings could form the basis for future research into natural aging processes and neurodegenerative diseases such as Alzheimer’s or Parkinson’s. The study is published in the journal Nature Neuroscience.

Nerve cells (neurons) are the most important building blocks of the brain. They form the basis for all mental and physical functions such as thinking, feeling, movement, and perception. In the course of life, in the brain can be lost for various reasons: They die off due to age-related processes, are damaged by toxins such as alcohol, or neurodegenerative diseases such as Alzheimer’s and Parkinson’s lead to a more rapid progressive loss of neurons.

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