The genome inside each of our cells is modeled by tension and torsion—due in part to the activity of proteins that compact, loop, wrap and untwist DNA—but scientists know little about how those forces affect the transcription of genes.
Category: biotech/medical – Page 300
A team of microchip engineers at Pragmatic Semiconductor, working with a pair of colleagues from Harvard University and another from Qamcom, has developed a bendable, programmable, non-silicon 32-bit RISC-V microprocessor. Their research is published in the journal Nature.
Over the past several years, hardware manufacturers have been developing bendable microprocessors for use in medical applications. A bendable device with bendable components would allow for the creation of 24-hour sensors that could be applied to any part of the body.
For this new project, the research team developed an inexpensive circuit board that could be bent around virtually any curved object. The material was made using indium gallium zinc oxide instead of the more rigid silicon.
A Princeton-led team of scientists has created the first detailed connectome of an adult fruit fly brain, a complex network with almost 140,000 neurons. This significant step in neuroscience was featured in Nature and involved contributions from various global institutions, highlighting both the complexity of the fly’s brain and the potential insights it offers into human neurological diseases.
Groundbreaking Brain Mapping: A Connectome for the Adult Fruit Fly
Researchers led by Princeton University have constructed the first detailed neuron-by-neuron and synapse-by-synapse roadmap through the brain of an adult fruit fly (Drosophila melanogaster), achieving a major milestone in brain research. This study is the flagship article in the October 2 special issue of Nature, which is devoted to the new fruit fly “connectome.”
Exclusive: Global trial finds treatment with amivantamab and lazertinib halts progression for average of 23.7 months.
Disabling a gene involved in metabolism rejuvenates cells’ ability to spin off new neurons.
Bioengineered breast reconstruction and augmentation — dr. luba perry, phd — CEO, reconstruct bio.
Dr. Luba Perry, Ph.D. is Co-Founder and CEO of ReConstruct Bio (https://wyss.harvard.edu/technology/r…), an innovative venture emerging from Harvard’s Wyss Institute (https://wyss.harvard.edu/team/advance…), aimed at redefining the fields of medical reconstruction and aesthetics with an initial application of their groundbreaking technology on breast reconstruction and augmentation. With a multidisciplinary team of experts, the ReConstruct Bio team has developed the BioImplant—a living, bioengineered tissue created from the patient’s own cells, to provide safer, more natural alternative to current standards, which are often associated with significant drawbacks and health concerns.
Dr. Perry also serves as a Senior Scientist at the Wyss Institute for Biologically Inspired Engineering working at the 3D Organ Engineering Initiative since 2018 and is leading a Wyss Validation Project aiming to fabricate vascularized functional tissues for transplantation. Her interest is in tissue and organ engineering, focusing on vascularization and implantation studies utilizing complex surgical models.
Dr. Perry’s background is in molecular biology, pharmacology, and biomedical engineering, with a Bachelor of Science — BS, Biology, Master of Science — MS, Molecular Pharmacology, and a Doctor of Philosophy — PhD, Biotechnology, all from Technion — Israel Institute of Technology. She also has industry experience in a vascular gene therapy company (MGVS, now VESSL Therapeutics).
#LubaPerry #Harvard #WyssInstitute #ReConstructBio #Aesthetics #3DOrganEngineering #BreastReconstruction #BreastAugmentation #Vascularization #Innervation #Fat #AdiposeTissue #BreastImplants #Organogenesis #OrganEngineering #TissueEngineering #Bioengineering #Organs #Tissues #MolecularPharmacology #Breasts #Nipples.
Particles that are larger than regular molecules or atoms yet remain invisible to the naked eye can form a variety of useful structures, including miniature propellers for microrobots, cellular probes, and steerable microwheels designed for targeted drug delivery.
Light sources, a form of particle accelerator, produce powerful beams of X-rays and other spectrums, enabling scientists to peer into the microscopic structure of materials without physically altering them.
These machines differ from other accelerators as they use oscillating magnetic fields to generate light directly. They play a crucial role across various scientific fields, from studying atomic structures with hard X-rays to examining electronic structures with terahertz waves.
Light sources are a type of particle accelerator that produce powerful beams of X-rays, ultra-violet, or infrared light. These beams are similar to how holding an envelope in front of a bright light can reveal something about what’s inside the envelope. But by using special types of light vastly more powerful than the X-ray machine in a doctor’s office, these light sources help scientists see inside matter. It’s like seeing inside an envelope without opening it. This gives scientists the power to reveal how materials behave at microscopic or nanoscale sizes as well as at ultrafast speeds.
Recent advancements in phonon laser technology, which utilizes sound waves rather than light, show promising new applications in medical imaging and deep-sea exploration.
A novel technique enhances these lasers by stabilizing and strengthening the sound waves, allowing for more precise and powerful outputs. This development not only improves existing uses in medical and underwater applications but also extends potential uses to material science and quantum computing.
Enhancing Phonon Laser Technology
UC San Diego’s study reveals that meth and PCP impair memory by causing neurons to switch from glutamate to GABA, a process reversible with specific treatments.
Sustained drug abuse can have many long-lasting effects, including memory loss and reduced cognitive functions, which can persist for years. Now, neurobiologists at the University of California San Diego have identified a reversible, shared mechanism in the brain by which drugs of different classes generate cognitive impairments.
Investigating mechanisms of drug-induced cognitive deficits.