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Lab-Grown “Mini-Brain” Learns Pong — Is This Biological Neural Network “Sentient”?

A leading neuroscientist claims that a pong-playing clump of about a million neurons is “sentient”. What does that mean? Why did Cortical Labs teach a lab-grown brain to play pong? To study biological self-organization at the root of life, intelligence, and consciousness. And, according to their website, “to see what happens.” What’s next for biocomputing?

CORRECTIONS/Clarifications:
- The cells aren’t directly frozen in liquid nitrogen — they are put in vials and stored in liquid nitrogen (and you can’t buy them legally without credentials) https://www.atcc.org/products/pcs-201-010
- The sentience of some invertebrates, like octopuses, is generally agreed upon. Prominent scientists affirmed non-human consciousness in the Cambridge Declaration on Consciousness: https://philiplow.foundation/consciousness/
- The “Neanderthal neurons” are human cells that are “Neanderthalized” using genetic engineering: https://www.youtube.com/watch?v=5FBxnkzI9HU

DISCLAIMER: The explanations in this video are those proposed by the researchers, or my opinion. We are far from understanding how brains, or even neurons, work. The free energy principle is one of many potential explanations.

Support the channel: https://www.patreon.com/IhmCurious.

Footage from Cortical Labs: https://www.youtube.com/watch?v=neV3aZtTgVM
NASJAQ’s interview with founder Hon Weng Chong: https://www.youtube.com/watch?v=Y1R5k5QWPsY
Cortical Labs website: https://corticallabs.com.

Full paper on DishBrain: https://www.cell.com/neuron/fulltext/S0896-6273(22)00806-6

How NAD Keeps Your Cells Energized and Slows Down Aging

NAD, a vital molecule for cellular energy and DNA

DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

The Floating Bed

#bed Year 2006


July 5, 2006 Given that we spend roughly a third of our life asleep, the humble bed has had remarkably little innovation pointed in its direction over the ages. So a new floating bed which hovers 40 cm above the floor represents a significant development in the design of sleeping apparatus. Debuting at the recent Millionaire Fair in Kortrijk, Belgium, the floating bed is the result of six years of development by Dutch architect Janjaap Ruijssenaars working with Bakker Magnetics. Using the power of permanent opposing industrial-strength magnets to enable it to float, the full scale bed can hold 900 kilograms of weight, while a smaller one fifth scale platform can safely hold 80 kilogams. Already people are beginning to see many applications for the simple yet visually arresting platforms ranging from the basis for a sofa, Coffee table, Japanese dining table and particularly in the display areas where museums and high-end visual merchandisers are beginning to conceptualise numerous creative uses.

Four thin cables assure its motionless position and form the only contact with the ground and the only other aspect which concerned us about what is essentially a stunningly simple device was the issue of sleeping in such close proximity to magnetic fields.

Janjaap assures us that should you feel inclined to slip your bankcard into your pyjamas, the magnetic field atop the unit is not enough to degauss the magnetic strip. The field below the unit is a different matter however, and given that the magnetic field is strong enough to suspend 900 kilograms, it’s not recommended that people with pacemakers go under the bed – so if you’re wearing a pacemaker and drop the strawberry lube while using the floating bed, it’d be advisable to ask your partner to retrieve it.

Experimental drug speeds up myelin repair, restoring vision in mice

Researchers at the University of Colorado Anschutz Medical Campus have found a promising drug candidate that could help restore vision in individuals with multiple sclerosis (MS) and other neurological conditions that damage neurons.

The study was published this week in the journal Nature Communications.

The drug, LL-341070, enhances the brain’s ability to repair damaged — the protective sheath around nerve fibers. Damage to myelin is a hallmark of diseases like MS, as well as a natural consequence of aging, often resulting in , loss of motor skills, and cognitive decline.

People Today Carry DNA from Neandertals. Here’s How It May Affect Our Brain and Behavior

The divide between their lineage and ours narrowed even further in 2010, when researchers published the first Neandertal genome sequence. Comparison of that ancient DNA with modern human DNA showed that the two species had interbred and that people today still carry the genetic fingerprint of that intermixing. Since then, numerous studies have explored the ways in which Neandertal DNA affects our modern physiology, revolutionizing our understanding not only of our extinct cousins but of ourselves as a hybrid species.

This area of research, clinical paleogenomics, is still in its infancy, and there are many complexities to unravel as we explore this new frontier. We therefore must take the findings from these studies with a grain of salt. Nevertheless, the research conducted to date raises the fascinating possibility that Neandertal DNA has wide-­reach­ing effects on our species—not only on general health but on brain development, including our propensity for conditions such as autism. In other words, DNA from our extinct relatives may, to some extent, shape the cognition of people today.

Breakthrough Process Turns CO2 and Electricity Into High-Protein Food

A study has introduced a novel bioprocess that transforms CO2 and electricity into single-cell protein (SCP), a sustainable food source rich in essential amino acids.

<div class=””> <div class=””><br />Amino acids are a set of organic compounds used to build proteins. There are about 500 naturally occurring known amino acids, though only 20 appear in the genetic code. Proteins consist of one or more chains of amino acids called polypeptides. The sequence of the amino acid chain causes the polypeptide to fold into a shape that is biologically active. The amino acid sequences of proteins are encoded in the genes. Nine proteinogenic amino acids are called “essential” for humans because they cannot be produced from other compounds by the human body and so must be taken in as food.<br /></div> </div>

This Company Is Trying To Bring The Woolly Mammoth And The Dodo Back To Life—A Biologist Explains

It’s a mission that is less a nostalgic yearning for a prehistoric past than it is a solution to combat climate change, the company’s founders have said. By reintroducing mammoths to Arctic environments, they hope to rejuvenate grasslands and reduce permafrost thaw—a major source of methane emissions.

The potential ripple effects of such an ecological intervention have raised profound ethical and scientific questions but have nonetheless captivated researchers, investors and the public alike.

Colossal Bioscience’s approach to de-extinction is rooted in cutting-edge advances in genetic engineering and synthetic biology.

Octopus Ink Extends Lifespan & Improves Cognition in Mice

New research from the Academy of Military Medical Sciences in Beijing has uncovered a rather intriguing finding: natural melanin nanozymes (NMNs) derived from octopus ink may potentially slow ageing, protect against neurodegenerative diseases, and extend lifespan. Published in ACS Omega, the study reveals how these nanozymes work at the cellular level to mitigate oxidative stress, improve gut health, and enhance brain function, offering a new frontier in anti-ageing and neurological research.

What are Melanin Nanozymes?

Melanin, best known as the pigment responsible for skin and hair colour, has also been recognized for its potent antioxidant properties. Nanozymes created from natural melanin, like those extracted from octopus ink, mimic the activity of antioxidant enzymes such as superoxide dismutase (SOD). These nanozymes neutralize free radicals, reduce oxidative stress, and improve cellular health—processes that are critical in mitigating ageing and the onset of neurodegenerative diseases.

Michael Levin Addresses Consciousness & the Mind-Body Problem

Daniel Dennett might be closer to truth on consciousness.


Full Episode: https://www.youtube.com/watch?v=kMxTS7eKkNM
Title: “Michael Levin: What Is The Field Of Diverse Intelligence (DI)? All Possible Intelligent Agents”

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Synthetic Biology: Rewriting Life. Andrew Hessel at NextMed Health

Synthetic Biology is on the cusp of revolutionizing biomedicine.
at NextMed Health 2023 (http://NextMedHealth.com)

Andrew Hessel is chairman of Project-write, and Author of The Genesis Machine, Our Quest to Rewrite Life in the Age of Synthetic Biology.

More about Andrew Hessel: https://www.nextmed.health/bio-andrewhessel.

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