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These people have got a leg — or an arm — up on the future.

Thanks to the latest advancements in medical science, amputees are becoming part robot, with awe-inspiring artificial limbs that would make Luke Skywalker jealous.

These new limbs come armed with microprocessors and electrodes that sense muscle movement. Others can be controlled by a smartphone app. People missing limbs often tried to hide their prosthetics, but these New Yorkers are showing them off with pride.
Rebekah Marine.

Rebekah Marine had the modeling bug from a young age, playing dress-up as a kid and getting her mom to take her to try out for modeling agencies in New York.

The one problem? She was born without part of her right arm.

“I was just kind of quickly denied from [agencies] based on my quote-unquote disability,” the 28-year-old says.

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A very interesting article about the state of funding for aging research and about Buck and ex Geron Mike West.


As I mentioned in last week’s letter, I traveled to San Francisco last Monday with my friend Patrick Cox, who writes our Transformational Technology Alert newsletter. We had dinner with Dr. Mike West of Biotime and then spent the next morning at the Buck Institute for Research on Aging. Pat and I decided we would jointly report on what we learned. He has already written his part, which was published last week. I am going to reproduce portions of that letter, which highlight the conversation with Brian Kennedy and his team at the Buck Institute, and then add my own thoughts about our conversation with Mike West the previous night.

(Note that I am excerpting Patrick’s paid letter, which includes comments on companies in his portfolio, rather than his free weekly Transformational Technologies Tech Digest service. We agreed that it was important to do so in this one case, given the huge significance of the research involved and the Buck Institute’s relationship to it.)

Essentially, we looked at two aspects of aging. The Buck Institute is focused on how to slow down the aging process and reduce the symptoms (such as chronic diseases) that come with aging. Dr. Mike West and his colleagues, as well as a few other firms and researchers, are focused on using our own pluripotent stem cells in ways that would allow us to repair organs in our bodies, thus giving us the opportunity to “grow younger” again. (It’s not quite that simple, as I’ll try to explain later.)

Current medical treatment boils down to six words: Have disease, take pill, kill something. But physician Siddhartha Mukherjee points to a future of medicine that will transform the way we heal.

TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design — plus science, business, global issues, the arts and much more.

Find closed captions and translated subtitles in many languages at http://www.ted.com/translate

Follow TED news on Twitter: http://www.twitter.com/tednews
Like TED on Facebook: https://www.facebook.com/TED

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This is our chance to make a real difference to how ageing research progresses and how people view ageing.

We need fifty people to make a real change in funding policy so we can work towards healthy longevity.

https://www.facebook.com/…/draft-zero-gsap-ageing-and-healt… (please make sure to complete the 6 first lines at least before sending to the email indicated there).


WHO GSAP draft, healthy longevity and biomedical aging research.

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More *!* — WOW — *!*
How can anyone NOT love science?!


Holograms (3-D light fields) can be projected from a 2-dimensional surface to control objects. (credit: Asier Marzo, Bruce Drinkwater and Sriram Subramanian)

British researchers have built a working Star-Trek-style “tractor beam” — a device that can attract or repel one object to another from a distance. It uses high-amplitude soundwaves to generate an acoustic hologram that can grasp and move small objects.

What is Ouro_botics?

Ouro_botics started life around four years ago on a kitchen table in Dublin.

Founder Jemma Redmond was working at the time on her masters thesis “An Investigation into Osteoblast Adhesion” and printed copies of finger bones (metacarpals, proximal & distal phalanges) which she then seeded with Osteoblasts and noticed growth was affected by structure.

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Losing hair can be a distressing experience for many people, but treatments are often ineffective, expensive or riddled with side effects. Could this development change that?

A study from Colombia University has shown blocking a certain family of enzymes can rapidly restore hair. The enzymes are called the Janus kinase (JAK) family, and two drugs have already been approved for blood diseases (ruxolitinib) and rheumatoid arthritis (tofacitinib), and are also undergoing other clinical trials.

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Viruses are usually thought of as agents of disease. But for the first time, scientists are poised to bring to the US market a virus that can help thwart cancer, a development that could herald a new age of viral therapies.

Approved by the Food and Drug Administration on Tuesday for treating advanced-stage melanoma, the virus — called Imlygic, which was developed in part in a Massachusetts lab — is a modified version of the herpes virus that both attacks the cancer and sparks the immune system into action against tumors.

In clinical trials, it has helped some cancer patients achieve remission with few of the nasty side effects common to existing treatments. And as the first tumor-killing virus to receive the FDA’s blessing, Imlygic could accelerate the development of other viral therapies.

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Adam Alonzi has made another excellent film about the power of gene therapy.

Narrated and produced by Adam Alonzi. Music arranged by Leslee Frost. Sponsored by BioViva Sciences Inc.

Alzheimer’s Disease.
Alzheimer’s disease is a progressive, neurodegenerative disorder. It is the leading cause of dementia. Typically the condition affects short-term memory, but as it advances it can result in disorientation, mood disorders, language difficulties and behavioral issues. Over time, body functions are lost, leading to death.

Current treatment options are extremely limited and the outlook is poor for sufferers with the average life expectancy being 3–9 years from diagnosis. According to RAND Corp, the average annual cost of care for someone with Alzheimer’s disease is $41,689 to $56,290.

Coronary artery structure being 3-D bioprinted (credit: Carnegie Mellon University College of Engineering)

Carnegie Mellon scientists are creating cutting-edge technology that could one day solve the shortage of heart transplants, which are currently needed to repair damaged organs.

“We’ve been able to take MRI images of coronary arteries and 3-D images of embryonic hearts and 3-D bioprint them with unprecedented resolution and quality out of very soft materials like collagens, alginates and fibrins,” said Adam Feinberg, an associate professor of Materials Science and Engineering and Biomedical Engineering at Carnegie Mellon University.

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