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Category: biotech/medical – Page 2,615

How to build synthetic DNA and send it across the internet

Biologist Dan Gibson edits and programs DNA, just like coders program a computer. But his “code” creates life, giving scientists the power to convert digital information into biological material like proteins and vaccines. Now he’s on to a new project: “biological transportation,” which holds the promise of beaming new medicines across the globe over the internet. Learn more about how this technology could change the way we respond to disease outbreaks and enable us to download personalized prescriptions in our homes.

Open Longevity School: Summer Camp 2018

Today we have a report from Open Longevity School: Summer Camp 2018, an initiative in Russia focused on developing a personal health and longevity strategy, Elena Milova went to investigate.

When we ask researchers when, in their opinion, the cures for aging will be ready, we often hear an optimistic answer: 20–25 years. As a well-informed optimist, I add another 10 years to this number, because wherever the therapies appear, it will take time for them to be distributed to other countries and become affordable. I will be happy if it takes less time, but what if it doesn’t? I am nearly 40, and when I add 35 years to my current age, I vividly imagine how my reflection in the mirror will show a 75-year-old lady. Honestly, I don’t want to see my body change, and it can explain why I aspire to get first-hand information about any means to slow down aging as soon as possible. Evidence-based information, of course.

Before I tell you my story of discovering how to control my aging, I must provide a disclaimer. This article does not contain any medical recommendations. The websites of the projects I will tell you about, once again, do not contain medical recommendations and cannot be independently used to make health decisions. The experience I will share, and the activities of the projects I will tell you about, are aimed at teaching you about the existing scientific knowledge about aging and interventions that have the potential to change the way we age. Whatever you decide to implement in your everyday life, please talk to your medical advisor first.

I am always looking for the means to keep myself as young as possible. Luckily for me, in Russia, there is a project focused on collecting this kind of information and making it publicly available. It is Nestarenie.ru (translation: “not aging”), an online encyclopedia created by professional sports trainer, valeologist and citizen scientist Dmitry Veremeenko. The amount of information that Dmitry has managed to process is hard to imagine; it consists of more than 70,000 scientific papers. The development of this database took him several years of work. Each article of his encyclopedia summarizes a specific drug, food or lifestyle element that can slow down or even reverse age-related changes, with a deep explanation of the underlying mechanisms. Each of his information-dense articles has lots of internal links to actual scientific papers (including the freshest meta-analyses) and finishes with a list of additional references.

Report on the 11th Annual Concertation and Consultation Workshop on Micro-Nano-Bio-Systems: MNBS 2017

This report covers the 11th edition of the EU-funded MicroNanoBio Systems cluster annual MNBS Bioelectronics Workshop, which took place in Amsterdam at the Beurs van Berlage on 12th-13th December 2017 and was included as part of the International Micro Nano Conference 2017, of which the main topics were Microfluidics and Analytical Systems, Fabrication and Characterization at the Nanoscale, and Organ-on-a-Chip.

Finger touching electronics board

New DNA Synthesis Method Could Soon Build a Genome in a Day

Synthetic biologists are the computer programmers of biology. Their code? DNA.

The whole enterprise sounds fantastical: you insert new snippets of DNA code—in the form of a chain of A, T, C, G letters—into an organism, and bam! Suddenly you have bacteria that can make anti-malaria drugs or cells that can solve complicated logic problems like a computer.

Except it’s not that simple. The basis of synthetic biology is DNA—often a lot of it, in the form of many genes. Making an average gene from scratch costs several hundreds of dollars and weeks of time. Imagine a programmer taking a month to type a new line of code, and you’ll likely understand a synthetic biologist’s frustration.

CERN chip enables first 3D color X-ray images of the human body

Medical X-ray scans have long been stuck in the black-and-white, silent-movie era. Sure, the contrast helps doctors spot breaks and fractures in bones, but more detail could help pinpoint other problems. Now, a company from New Zealand has developed a bioimaging scanner that can produce full color, three dimensional images of bones, lipids, and soft tissue, thanks to a sensor chip developed at CERN for use in the Large Hadron Collider.

Mars Bioimaging, the company behind the new scanner, describes the leap as similar to that of black-and-white to color photography. In traditional CT scans, X-rays are beamed through tissue and their intensity is measured on the other side. Since denser materials like bone attenuate (weaken the energy) of X-rays more than soft tissue does, their shape becomes clear as a flat, monochrome image.

Researchers confine mature cells to turn them into stem cells

Recent research led by Professor G.V. Shivashankar of the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) and the FIRC Institute of Molecular Oncology (IFOM) in Italy, has revealed that mature cells can be reprogrammed into re-deployable stem cells without direct genetic modification — by confining them to a defined geometric space for an extended period of time.

“Our breakthrough findings will usher in a new generation of stem cell technologies for tissue engineering and regenerative medicine that may overcome the negative effects of geonomic manipulation,” said Prof Shivashankar.

Standard type 2 diabetes treatments may not improve the condition in youth

A new study by the Yale scientists, taking insulin or the most commonly used drug for type 2 diabetes, metformin, failed to either delay or effectively treat the condition in youth.

In the study, dubbed as Restoring Insulin Secretion (RISE) Pediatric Medication Study, scientists explored the impact of two medications for pre-diabetes or diabetes in youth aged 10 to 19. The children and teens either took infusions of insulin for three months, trailed by metformin for a year, or metformin alone. Amid the 15-month contemplate period, the analysts surveyed glucose levels of study members and also the capacity of their beta cells, which store and discharge insulin keeping in mind the end goal to keep up solid glucose.

Scientists discovered that the medications neglected to moderate or stop the progression of type 2 diabetes in either group. The working of the adolescents’ beta cells kept on breaking down in spite of the treatments, which have been appealed to treat write 2 diabetes adequately in adults.