Lifeboat Foundation

Micro- and nanoscale robots that can effectively convert diverse energy sources into movement and force represent a rapidly emerging and fascinating robotics research area. Recent advances in the design, fabrication, and operation of micro/nanorobots have greatly enhanced their power, function, and versatility. The new capabilities of these tiny untethered machines indicate immense potential for a variety of biomedical applications. This article reviews recent progress and future perspectives of micro/nanorobots in biomedicine, with a special focus on their potential advantages and applications for directed drug delivery, precision surgery, medical diagnosis, and detoxification.

Scientists are beginning to realize that many cellular behaviors, such as metastasizing cancer cells moving through the body or wound healing, aren’t random events, but the result of coordinated actions by cells.

Such collective cell movement requires communication, and a new study shows that cells are most effective at communication when they aren’t tightly packed together. This was a surprise, says Andrew Mugler, a Purdue University assistant professor of physics and astronomy who studies cell behavior.

“Our hypothesis was proven wrong,” Mugler says. “Our hypothesis was that cells that are closer to each other should experience a sensory improvement. Instead, we found that long-range communication was better, even though it meant that cells had to be receiving weaker communication signals.”

Speaking at the Aspen Abu Dhabi Ideas Forum, Dr Brad Perkins, chief medical officer, Human Longevity, said: “Right now the most daunting and expensive human health problem that the world is facing is age related chronic disease. Our hypothesis at Human Longevity is that genomics and the technologies that support its application in medicine and drug discovery are going to be the next accelerant in extending a high performance human lifespan.

Human Longevity Inc has been funded with over $220 million and was founded by Craig Venter, Peter Diamandis and Robert Hariri.

Dr. Brad Perkins and other anti-aging researchers at commercial companies made the more conservative for anti-aging researchers that within about 40 years human longevity (maximum lifespan) will reach 140 years. Current life expectancy is about 80 years but with some countries and states at about 90 years for women. The confirmed longest lived person reached 122 years of age.

Continue reading “Future Human lifespan 140 years, 500 years, 1000 years or indefinite with aging damage repair and aging reversal” »

Every day in a San Diego lab, raw material derived from donated tissue unsuitable for organ transplantation goes into a machine, and three-dimensional human liver tissue is printed out.

Pioneered by a company called Organovo, this 3D bioprinting technology may one day achieve the Holy Grail of its industry: the manufacturing of whole human organs to replace damaged ones. But for now, it’s already making an impact on human health, as pharmaceutical and biotech companies are using its manufactured human liver tissue to test the toxicity of new drugs and therapies.

Organovo is developing multiple tissue types for therapeutic use, with strong early results in animal models. In three to five years, there’s a good chance that it will have an Investigational New Drug Application in at least one tissue. The company’s strategic plan is coming to fruition just as its chief scientific officer, Sharon Presnell, envisioned when she joined the startup in 2011.

I did a long-form interview on Medium’s Defiant of my run for California Governor. It covers many subjects (Trump, gene editing, basic income), as well as why I think technology is ready to change politics and governance forever:

By AJAI RAJ

Stop me if you’ve heard this one before. It’s 2015, and the ever-humming machinery of American presidential politics is picking up steam. The American political machine runs on steam, okay? It’s very old.

Continue reading “Zoltan Istvan Wants to Create Superpeople —Oh, and Also Be California’s Governor” »

As I start to look at the emerging trends of 2017 from the vantage of IndieBio, where we see hundreds of biotech startup applications and technologies per year, a few key themes are already emerging. Even as political landscapes change, science and technology continue to push forward.

1. Cell Therapies and Regenerative Medicine

Most of us have seen science fiction shows that show future doctors regrowing and replacing entire organs. That fiction is now becoming a reality with cell therapies from companies like Juno (curing two infants with leukemia of their previously treatment resistant cancers with engineered T-cells), induced pluripotent stem cells (iPS) pioneered by the Nobel prize winning scientist, Shinya Yamanaka that can become any cell in the body, growing organoids (mini organs with some function of a fully grown organ like the stomach organoids grown by researchers in Ohio), and entirely re-grown organs.

Continue reading “3 Exciting Biotech Trends to Watch Closely in 2017” »

By Matt Reynolds

By making DNA endlessly change, researchers have shown how a biological computer might one day solve problems much faster than conventional computers or even quantum computers. It’s still a long way from being functional though.

The DNA-based system is an experiment in how it may be possible to make a theoretical type of computer known as a non-deterministic universal Turing machine.

Continue reading “First hint of how DNA calculators could supercharge computing” »

The goal of transcending flesh is an old fetish. Yogis meditated and fasted for eons in order to rise above our ‘meat casing,’ performing painful ablutions and inventing kriyas, intense breathing exercises that are physiologically indistinct from intentional hyperventilation. The goal of many religions, from some forms of Tibetan Buddhism to numerous strains of Christianity and Islam, is all about letting the spirit soar free.

While language changes, pretensions remain. Today we talk about ‘uploading consciousness’ to an as of yet discovered virtual cloud. Artificial intelligence is only moments away, so the story goes, with experts weighing in on the ethical consequences of creating machines void of emotional response systems. In this view consciousness, itself a loaded and mismanaged term, is nothing more than an algorithm waiting to be deciphered. Upon cracking the code, immortality awaits.

Of course others are more grounded. The goal of extending life to 150 years includes the body by default, though the mind is still championed above all else. Yet we seem to age in opposing directions by design. At forty-one little has changed in how I think about myself, yet my body is decaying: a post-knee surgery creek here, a perpetual tight shoulder there. It certainly feels like a slowly approaching transition, even if that, like much of life, is an illusion.

Continue reading “From AI to Anxiety Relief, The Brain Needs a Body” »

The quest to read emotions from brain scans.