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Category: biotech/medical – Page 2523

Summary: The mitochondrial free radical theory of aging says that if we consume antioxidant supplements, we can repair the damage caused by free radicals. However, this recommendation is contradicted by a large body of evidence which shows that antioxidant supplements are often harmful. Researchers are discovering more effective ways to improve health by clearing our mitochondrial damage caused by free radicals.

Are you killing yourself in a bid to live a longer healthier life?

A growing body of evidence shows that if you take antioxidant supplements, and you are otherwise healthy, then you are wasting your money, and damaging your liver and nervous system.

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Summary: A new report on mitochondria and cancer shows how our mitochondria help our cancers to grow. With its 37 genes, mitochondria are an attractive druggable target and researchers are looking it as an angle to develop powerful cancer cures. Cover Photo: FatCamera – iStock/Getty Images.

Scientists believe the cure for cancer lies within our mitochondria.

Once considered an academic backwater, researchers suddenly have a renewed interest in the metabolism of cancer cells and are focusing on the lowly mitochondrion. New research shows that the mitochondria within our bodies bend over backward to help cancer cells grow. Scientists are publishing increasing amounts of evidence showing that cancer-induced changes in our mitochondria contribute to the growth of cancer. As Dr. Dario C Altieri, Head of the Altieri Lab at the Wistar Institute said in a review in the July 2017 British Journal of Cancer.

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Most people don’t realize that all human beings have two sets of DNA in their bodies, the DNA inside our chromosomes, and a foreign DNA inside our mitochondria, that our ancestors stole from bacteria over a billion years ago.

Look into any of your cells, and you’ll see mysterious foreign DNA lurking inside your mitochondria, the tiny organelles that litter your cells. Recently, mitochondria have come under a growing scientific spotlight; scientists increasingly believe they play a central role in many, if not most, human illnesses. Mitochondria are the powerhouses of the cell, and when they falter, our cells lose power, just as a flashlight dims when its batteries weaken. Recently, researchers have linked mitochondria to an array of metabolic and age-related maladies, including autism, type 2 diabetes, cancer, Alzheimer’s, Parkinson’s, and cardiovascular disease.

While our mitochondria did not come from another planet, they might as well have. Peer through a microscope, and you’ll swear that tiny aliens have invaded your cells. You are partially correct. Mitochondria appear out of place compared to the other structures within the cell. Something ‘alien’ has invaded our cells, eons ago, but it came from primordial bacteria, a distinctly terrestrial source.

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Cellulose is the most abundant organic polymer in the world. It is the primary compound in the cell walls of green plants, and is typically used to make paper and cardboard.

At the VTT Technical Centre of Finland, a state owned research and development non-profit, scientists have used nano-structured cellulose to make a 3D printable material.

The nanocellulose paste is now in development to make smart-dressings that heal and monitor skin wounds.

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For much of human history, living up to a ripe old age was seen as a gift from the gods, an aberration, or just the product of sheer luck. Given that up to the beginning of the twentieth century many of us succumbed to disease at an early age, being extremely fortunate to live anywhere past the age of forty, it should be no surprise that living a long life is still beatified today as something akin to winning the lottery.

Even when confronted with the galloping pace of scientific advances in human longevity, our historical sensibilities have led us to take a defeatist stance towards the subject: “Even if longevity interventions become available during my lifetime, I am already too late to take advantage of them, so why bother?”

Indeed, this hesitation to see human life extension as a real possibility in our lifetime, dismissing it as a dream belonging to the realms of science fiction[1] and futuristic utopias[2] is not an uncommon one, and as long as tangible rejuvenation therapies do not become available, we will feel validated in our pragmatism.

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My new story for my #transhumanism column at Psychology Today on Direct Neurofeedback:

Transhumanism—the movement of using science and technology to improve the human being—covers many different fields of research. There are exoskeleton suits to help the disabled; there are stem cell treatments to cure disease; there are robots and AI to perform human chores. The field is wide open and booming as humanity uses more and more tech in its world.

It’s not that often I get to participate directly in these radical technologies, but I did so recently when Grant Rudolph, Clinical Director at Echo Rock Neurotherapy in Mill Valley, California invited me to try his Direct Neurofeedback techniques. Via his computer and EEG wire hookups, Mr. Rudolph echoed my brainwave information back into my head at an imperceptible level. I did two sessions of Direct Neurofeedback.

At first, I was skeptical that I’d even feel anything since the EEG information can’t be detected by the skin as a sensation, but within five minutes of having the wires stuck onto my forehead, I began feeling different. I can compare it to a light dose of a recreational drug: I felt happy, content, and worry-free. I also felt more introspective than normal. The feedback only took a few seconds, and after about 15 minutes, I seemed to notice the world’s colors were sharper and my hearing was more acute. The heightened awareness and calming effect lasted about 24 hours and then most of it gradually wore off. Some of the clarity must still be working, because getting things done sometimes still seems easier. I’m told that continued sessions would make this state of clarity my new norm.

Continue reading “I Tried Direct Neurofeedback and the Results Surprised Me” | >

At well over $150,000 per appliance, the Volta GPU based DGX appliances from Nvidia, which take aim at deep learning with framework integration and 8 Volta-accelerated nodes linked with NVlink, is set to appeal to the most bleeding edge of machine learning shops.

Nvidia has built its own clusters by stringing several of these together, just as researchers at Tokyo Tech have done with the Pascal generation systems. But one of the first commercial customers for the Volta based boxes is the Center for Clinical Data Science, which is part of the first wave of hospitals set to use deep learning for MR and CT image analysis.

The center, which is based in Cambridge, Massachusetts, has secured a whopping four DGX-1 Volta appliances, which sport the latest GPUs with eight per node with the NVlink interconnect. The Next Platform talked with Neil Tenenholtz, senior data scientist at the center, about where deep learning will yield results for hospitals and medical research and about their early experiences with the four machines.

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The new self-propelled, cancer-seeking bacteriobot swims right into the tumor and zaps it with a deadly payload of cancer drugs.

The recently perfected #bacteriobot holds ‘a lot of promise’ in treating #cancer says a physician. Cancer patients at a hospital in Montreal may be the first to be treated with these #nanorobots built out of bacteria.

Summary: The recently perfected bacteriobot holds ‘a lot of promise’ in treating cancer says a physician. Cancer patients at a hospital in Montreal may be the first to be treated with nanorobots built out of bacteria. The new self-propelled, cancer-seeking bacteriobot swims right into the tumor and zaps it with a deadly payload of cancer drugs. [Cover image: Getty Images/iStock.]

Google’s Futurist Ray Kurzweil once said that within decades, we will have nanobots, swimming through our veins keeping us healthy. The tiny robots will keep us healthy by correcting DNA errors, removing toxins, extending our memories and zapping cancer. The Futurist said that back in 2007, and his prophecy is becoming a reality, at least in the treatment of cancer.

Continue reading “Bacteriobot Holds ‘A Lot Of Promise’ To Treat Cancer, Says Doctor” | >

Full Interview ► https://goo.gl/PvUjjU

Michael B. Fossel, M.D., Ph.D. (born 1950, Greenwich, Connecticut) was a professor of clinical medicine at Michigan State University and is the author of several books on aging, who is best known for his views on telomerase therapy as a possible treatment for cellular senescence. Fossel has appeared on many major news programs to discuss aging and has appeared regularly on National Public Radio (NPR). He is also a respected lecturer, author, and the founder and former editor-in-chief of the Journal of Anti-Aging Medicine (now known as Rejuvenation Research).

Prior to earning his M.D. at Stanford Medical School, Fossel earned a joint B.A. (cum laude) and M.A. in psychology at Wesleyan University and a Ph.D. in neurobiology at Stanford University. He is also a graduate of Phillips Exeter Academy. Prior to graduating from medical school in 1981, he was awarded a National Science Foundation fellowship and taught at Stanford University.

In addition to his position at Michigan State University, Fossel has lectured at the National Institute for Health, the Smithsonian Institution, and at various other universities and institutes in various parts of the world. Fossel served on the board of directors for the American Aging Association and was their executive director.

Continue reading “M. Fossel — How to Reverse Aging” | >

Shai Ben-David, Professor at the University of Waterloo, gave Machine Learning Course composed of 23 Lectures (CS 485/685) at the University of Waterloo on Jan 14, 2015…

Machine learning is the science of getting computers to act without being explicitly programmed. In the past decade, machine learning has given us self-driving cars, practical speech recognition, effective web search, and a vastly improved understanding of the human genome. Machine learning is so pervasive today that you probably use it dozens of times a day without knowing it. Many researchers also think it is the best way to make progress towards human-level AI.

Shai Ben-David holds a PhD in mathematics from the Hebrew University is Jerusalem. He has held postdoctoral positions at the University of Toronto in both the Mathematics and CS departments. He was a professor of computer science at the Technion in Haifa, Israel. Ben-David has held visiting positions at the Australian National University and Cornell University, and since 2004 has been a professor of computer science at the University of Waterloo in Canada.

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