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Category: biotech/medical – Page 2,479

GIOSTAR Announces FDA Approval Under Compassionate Use for a COVID-19 Clinical Trial with Stem Cells

SAN DIEGO, May 4, 2020 /PRNewswire/ — Global Institute of Stem Cell Therapy and Research (GIOSTAR), the worldwide leader in stem cell research, is pleased to announce that they have received an approval for a COVID-19 clinical trial, led by their Medical Director Dr. Prabhat Soni. GIOSTAR will conduct the trial using stem cells to treat COVID-19 patients, under the approval of the United States Food and Drug Administration (FDA) “expanded access for compassionate use” program. The Institute is exploring a promising alternative approach to the devastating disorder, which leverages the anti-inflammatory properties of mesenchymal stem cells (MSCs). According to Dr. Soni, the investigation is based upon two decades of stem cell research by GIOSTAR Co-Founder, Chairman and Chief Scientific Officer Dr. Anand Srivastava.

Scientists uncover secret behind molecule that blocks HIV infection

Rhesus macaques don’t monkey around when it comes to HIV; they have a protein that effectively disables invading HIV particles.

A group of University of Chicago scientists announced an innovative study that explains how the macaques’ immune protein, called TRIM5α, works its magic. It also represents a significant step forward in the science of modeling how complex biological proteins assemble themselves, the scientists said.

“These proteins work together to encase the HIV capsid in a hexagonal net and restrict viral activity,” said postdoctoral fellow Alvin Yu and lead author of the study, which was published in Nature Communications.

How Bill Gates Monopolized Global Health

TRANSCRIPT AND MP3: www.corbettreport.com/gates

Who is Bill Gates? A software developer? A businessman? A philanthropist? A global health expert? This question, once merely academic, is becoming a very real question for those who are beginning to realize that Gates’ unimaginable wealth has been used to gain control over every corner of the fields of public health, medical research and vaccine development. And now that we are presented with the very problem that Gates has been talking about for years, we will soon find that this software developer with no medical training is going to leverage that wealth into control over the fates of billions of people.

Científicos australianos trabajan con medicamento que puede matar al COVID-19 en 48 horas

Australian scientists work with medicine that can kill COVID-19 in 48 hours59.

“En tiempos en los que estamos teniendo una pandemia global y no hay un tratamiento aprobado, si tuviéramos un compuesto que ya estuviera disponible en todo el mundo, eso podría ayudar a la gente antes. Siendo realistas –consideró la investigadora-, pasará un tiempo antes de que una vacuna esté ampliamente disponible”.

Aunque no se conoce el mecanismo por el que la ivermectina actúa en el coronavirus, teniendo en cuenta su acción en otros virus, “es probable que funcione para detener la capacidad del virus de ‘amortiguar’ la capacidad de las células anfitrionas para eliminarlo”, dijo Wagstaff.

El uso de esta medicina para combatir la COVID-19 dependería, según la científica, de los resultados de más pruebas preclínicas y, en última instancia, de ensayos clínicos, con una financiación que se necesita urgentemente para seguir avanzando en el trabajo.

Could Deep Breathing Exercises Protect You From the Worst Symptoms of COVID-19?

Deep Breathing alone will not create new lung cells, but combined with deep relaxation, guided visualizations, and therapeutic messages (Your stem cells are going to transform themselves into new lung cells to replace those lung cells infected by the Coronavirus. Your stem cells are going to change themselves into T-Cells, B-Cells, and Natural Killer Cells which are going to seek out, identify, attack, and destroy all the Coronavirus cells in your entire body), it will eliminate the coughing, fever, headaches, inflammation, and breathing problems.

While there is no hard evidence that lung exercises can help ease the discomfort and the progression of symptoms of COVID-19, there are techniques that will restore your lungs to optimal health.

Elon Musk and Grimes share first photo of their baby covered in tattoos — and claim he’s called ‘X Æ A-12’

ELON Musk shared the first photos of his newborn son with singer Grimes on Tuesday.

The Tesla CEO, 48, posted a cute snap of their sleeping baby using a face tattoo filter, as well as one of him cradling the newborn at the hospital on Twitter.

Responding to a fan who said their son is “gorgeous”, Elon joked about the tattoos: “Thanks smile Never too young for some ink haha.”

Epidemiologists develop new tool for measuring the pace of aging across the life course

A study just released by Columbia University Mailman School of Public Health is reporting a blood-DNA-methylation measure that is sensitive to variation in the pace of biological aging among individuals born the same year. The tool—DunedinPoAm—offers a unique measurement for intervention trials and natural experiment studies investigating how the rate of aging may be changed by behavioral or drug therapy, or by changes to the environment. The study findings are published online in the journal eLife.

“The goal of our study was to distill a measurement of the rate of biological aging based on 12-years of follow-up on 18 different clinical tests into a blood test that can be administered at a single time point.” said lead author Daniel Belsky, Ph.D., assistant professor of epidemiology at Columbia Mailman School and a researcher at the Columbia Aging Center.

Midlife adults measured to be aging faster according to the new measurement showed faster declines in physical and cognitive functioning and looked older in facial photographs. Older adults measured to be aging faster by the tool were at increased risk for chronic disease and mortality. In other analyses, the researchers showed that DunedinPoAm captured new information not measured by proposed measures of biological aging known as epigenetic clocks, that 18-year-olds with histories of childhood poverty and victimization showed faster aging as measured by DunedinPoAm, and that DunedinPoAm predictions were disrupted by a caloric restriction intervention in a randomized trial.

Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19

Ketamine and Naltrexone you say? Weird.

Ideal new treatments for Novel Coronavirus-19 (COVID-19) would help halt the progression disease in patients with mild disease prior to the need for artificial respiration (ventilators), and also provide a rescue treatment for patients with severe disease, while also being affordable and available in quantities sufficient to treat large numbers of infected people. Low doses of Naltrexone, a drug approved for treating alcoholism and opiate addiction, as well as Ketamine, a drug approved as an anesthetic, may be able to interrupt the inflammation that causes the worst COVID-19 symptoms and prove an effective new treatment. This study will investigate their effectiveness in a randomized, blinded trial versus standard treatment plus placebo.

Detailed Description:

There is an urgent need to develop new treatments for Novel Coronavirus-19 (COVID-19) infection using easily available and affordable medications. We need to develop a treatment protocol which prevents progression of the disease and a treatment protocol to rescue those with advanced disease. In addition to anti-viral therapeutics currently under investigation in other trials, the addition of immunomodulators to the treatment regimen appears have to potential to act as agents which can reduce the pathogenicity of this disease by reducing the dysregulation of autoimmunity which is destructive of normal tissue and when unchecked rapidly leads to mortality.

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