A pioneer of the Crispr gene-editing technology that’s taken Wall Street by storm says the field is probably five to 10 years away from having an approved therapy for patients.
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Category: biotech/medical – Page 2,397
Today, we want to draw your attention to a recent study showing an association between the accumulation of Tau proteins, which are misfolded proteins that typically indicate Alzheimer’s disease and senescent cells.
Unfortunately, this journal paper is hidden behind a paywall, as is 70% of scientific data; this is an unacceptable situation for science and the sharing of knowledge. However, thanks to the work of Sci-Hub, a website that bypasses paywalls and offers free access to all scientific papers, you can read it without spending a dime.
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Scientists in the US may be out in front developing the next generation of Crispr-based genetic tools, but it’s China that’s pushing those techniques toward human therapies the fastest. Chinese researchers were the first to Crispr monkeys, and non-viable embryos, and to stick Crispr’d cells into a real live human. And now, a team of scientists in China have used a cutting-edge Crispr technique, known as base editing, to repair a disease-causing mutation in viable human embryos.
Published last week in the journal Molecular Therapy, and reported first by Stat, the study represents significant progress over previous attempts to remodel the DNA of human embryos. That’s in part because the editing worked so well, and in part because that editing took place in embryos created by a standard in-vitro fertilization technique.
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Research involving 1,000 scientists finds scores of genetic markers that identify people most likely to develop diseases.
Ian Sample, science correspondent.
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Bacteria found in the human gut could save countless lives by transforming type A or type B blood into type O.
At a meeting of the American Chemical Society today, Steve Withers of the University of British Colombia presented new research suggesting enzymes found in gut bacteria could effectively strip antigens from the two most common blood types. If successful, the discovery would essentially make most types of blood accessible to those who need it, regardless of their blood type.
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The Many Yous
Posted in biotech/medical
If you’ve read some of my latest articles, you might remember that I’ve been spending some time in my hometown. My quasi-holiday is not over yet, but my stay in my hometown pretty much is; I’m leaving in a few hours.
During my stay, I’ve told my girlfriend many times that wandering around my hometown feels like having someone else’s memories implanted in my head. I’ve never considered myself too attached to the place where I grew up, but after years of absence, I’ve become even less so. It’s like the place doesn’t have an effect on me anymore; it can’t really influence me. I know my way around it and I remember where landmarks and things are, but there’s little emotional connection left. It’s almost like being a tourist. Even my own room, which used to be pretty much my realm up until I was 18, now feels just like any regular room—in no small part because it has changed quite a bit since then. Given a few more years, I might lose all feelings for the place.
This shouldn’t be a surprise. Your feelings for places and people change and sometimes fade away altogether, over the years. This happens within currently normal lifetimes; what is going to happen if and when our lives last for centuries?
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Healthy diet linked to healthy aging and longer telomeres, a new study on 5000 healthy adults. Relationship significant in women. … All four diets emphasize eating plenty of fruits, vegetables, whole grains and plant-based protein and limiting consumption of sugar, sodium and red and processed meat. Overall, the findings suggest that following these guidelines is associated with longer telomere length and reduces the risk of major chronic disease…”
Eating a diet that is rich in fruits, vegetables and whole grains and low in added sugar, sodium and processed meats could help promote healthy cellular aging in women, according to a new study published in the American Journal of Epidemiology.
“The key takeaway is that following a healthy diet can help us maintain healthy cells and avoid certain chronic diseases,” said lead author Cindy Leung, assistant professor of nutritional sciences at the University of Michigan School of Public Health. “Emphasis should be placed on improving the overall quality of your diet rather than emphasizing individual foods or nutrients.”
In the study, researchers used telomere length to measure cellular aging.