Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biotech/medical – Page 2199

Thirty-three older adults between the ages of 58 and 95 applied the cream all over their bodies twice a day for 30 days. After a month, the researchers measured blood levels of three cytokines—interleukin-1 beta, interleukin-6, and tumor necrosis factor (TNF) alpha—that have all been implicated in age-related inflammatory diseases. Using the cream reduced the amount of all three cytokines compared to both the participants’ levels before using the cream and the levels of similarly aged adults who did not use the cream. In fact, using the cream lowered participants’ cytokine levels to be nearly equivalent with people in their 30s, suggesting that rejuvenating the skin can reverse “inflamm-aging.” The cream also improved skin hydration, lowered pH, and repaired the permeability barrier.

Skin is the body’s largest organ, and scientists at UC San Francisco and the San Francisco Veterans Administration (VA) Health Care System think it may be to blame for body-wide inflammation linked to numerous chronic diseases of aging. The good news is that properly caring for the skin with a moisturizing cream may lower inflammation levels and potentially prevent age-related diseases, according to a new clinical pilot study.

Two people holding coffee.
As humans get older, we experience a low-level of inflammation—dubbed “inflamm-aging”—driven by an increase in molecules in the blood called cytokines. This age-related inflammation has been linked to serious chronic diseases, including Alzheimer’s disease, cardiovascular disease, and diabetes. Scientists initially thought that the inflammation stemmed from the immune system or the liver, but a group of dermatologists at UCSF have a different theory.

“The inflammation must come from an organ big enough that very minor inflammation can affect the whole body. Skin is a good candidate for this because of its size,” said study senior author Mao-Qiang Man, MD, a research scientist in the UCSF Department of Dermatology, who is based at the San Francisco VA Health Care System and is also a visiting professor at Southern Medical University in Guangzhou, China. “Once we get old, we have dermatological symptoms like itchiness, dryness, and changes in acidity. It could be that the skin has very minor inflammation, and because it’s such a large organ it elevates circulating cytokine levels.”

Continue reading “Skin Repair Eliminates ‘Inflamm-Aging’ Linked to Chronic Disease” | >

Good for Amazon.

Amazon has removed the online listings for two books that claim to contain cures for autism, a move that follows recent efforts by several social media sites to limit the availability of anti-vaccination and other pseudoscientific material.

The books, “Healing the Symptoms Known as Autism” and “Fight Autism and Win,” which had previously been listed for sale in Amazon’s marketplace, were not available on Wednesday. The company confirmed that the listings had been removed, but declined to discuss why or whether similar books would be taken down in the future.

Several such books were still listed on Wednesday. In an article published this week, Wired magazine noted that Amazon is crowded with titles promoting unproven treatments for autism that include “sex, yoga, camel milk, electroconvulsive therapy and veganism.”

Continue reading “Amazon Pulls 2 Books That Promote Unscientific Autism ‘Cures’” | >

“Our findings represent a dramatic divergence from the current dogma, which works primarily on the premise that neurotransmitters like serotonin and dopamine act solely through the activation of their membrane receptors in the brain to regulate brain cell activity,” says Ian Maze, PhD, Assistant Professor of Neuroscience, and Pharmacological Sciences, at the Icahn School of Medicine at Mount Sinai, and senior author of the paper. “We found actions of these brain chemicals that are independent of neurotransmission but critically important to their overall signaling, suggesting that our current understanding of these molecules is incomplete and requires further investigation.”

Findings could fundamentally change how scientists interpret the biological activities of serotonin.

Read more

In April of 2019 Google+ is going away. However, if you have stuff that you really want to save someone created a workaround. You can now move your content to Discourse.

Google+ is dead. Granted people have been saying that much for years now, but this time it’s really true. As of April, Google’s social media experiment will officially go the way of Reader, Buzz, Wave, Notebook, and all the other products that the search giant decided they were no longer interested in maintaining. Unfortunately in the case of Google+, the shutdown means losing a lot of valuable content that was buried in the “Communities” section of the service. Or at least that’s what we all thought.

Thanks to the efforts of [Michael Johnson], many of those Google+ communities now have a second chance at life. After taking a deep dive into the data from his own personal Google+ account, he realized it should be possible to write some code that would allow pulling the content out of Google’s service and transplanting it into a Discourse instance. With some more work, he was even able to figure out how to preserve the ownership of the comments and posts. This is no simple web archive; you can actually log into Discourse with your Google account and have all of your old content attributed to you.

To date, [Michael] has managed to transplant over 40,000 posts and around into “The Maker Forums”. With a few more weeks until the lights officially go out over at Google+, he says there’s still time to scrape more data out of the service if anyone has suggestions on maker-related content that they think is worthy of preservation. Of course, as all the code for the project as been released as open source, there’s still hope for the non-technical Communities should anyone want to spearhead the effort to duplicate those as well.

Continue reading “Google+ Communities Won’t Go Down Without a Fight” | >

Dr. Snyder is Director of the Center for Stem Cells and Regenerative Medicine at Sanford-Burnham Medical Discovery Institute.

“Evan needs no introduction to anyone who works in regenerative medicine; he has been at the pinnacle of that field for decades. I’ve been delighted that SENS Research Foundation has been able to work closely with him over the past few years, especially in the form of his annual hosting of some of our outstanding summer interns — he doesn’t even vet them himself anymore, because he knows how stellar our recruits invariably are! I’m intensely proud to have such a titan of our field on the Undoing Aging program”, says Aubrey de Grey.

Read more

The threat of pandemic influenza is ever-present. A pandemic can arise when a new influenza virus that hasn’t affected humans before emerges, spreads and causes illness in humans.

Influenza viruses are unpredictable – we can never be certain of when or from where the next pandemic will arise. However, another influenza pandemic is inevitable. In this interconnected world, the question is not if we will have another pandemic, but when.

To protect people across the globe from this threat, the WHO has released a Global Influenza Strategy for 2019–2030. The new strategy is the most comprehensive and far reaching influenza strategy that WHO has developed. The strategy outlines a framework for WHO, countries and partners to work together to prepare for, prevent, and control the influenza.

Read more

And Vetek Association present their list of the top 60 Longevity Influencers in Israel, whose efforts in science, technology, industry and policy are driving the growth of the Israeli Longevity Landscape.

Link to the Report: https://www.aginganalytics.com/longevity-in-israel

Aaron Ciechanover Anat Ben-Zvi, Ph.D., Clinical Psychologist Boaz Misholi Dov Chernichovsky — דב צ’רניחובסקי Ehud Cohen Eyal banin Idan Segev Ilia Stambler Israel Issi Doron Itamar Harel Itamar Raz Jonathan Mandelbaum Michael Neeman Mooly Eden Nir Barzilai MD Rafi Eitan Raphael Gorodetsky Ruth Arnon Uri Alon Valery Krizhanovsky Yael Sorek-benvenisti Yechezkel Barenholz Yosef Gruenbaum.

Read more