Archive for the ‘biotech/medical’ category: Page 2075

Jun 16, 2017

Head Transplant Doctor Reports Successful Repair of Spinal Cord in Rats

Posted by in category: biotech/medical

A head transplant doctor claims to have made advance toward realizing the medical procedure, but the scientific community remains skeptical. The team claims to have used a proprietary “glue” to repair the severed spines of rats and achieved full recovery.

Sergio Canavero, a man who has made the goal of his life’s work to transplant a human head onto a donor body, is claiming a success. He and his team have reported seemingly positive results from a technique called the Gemini Protocol. They used the protocol to repair severed spinal cords in rats, and their findings indicate that their methodology works “across the board.”

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Jun 16, 2017

LEAF Panel: How to Promote Longevity? ft. Drs. Aubrey de Grey, Alexandra Stolzing, Oliver Medvedik

Posted by in categories: biotech/medical, life extension

On the 9th of June we teamed up with the Major Mouse Testing Program (MMTP) for a live stream longevity panel on the MMTP Facebook page. The panel included Dr. Alexandra Stolzing, Dr. Aubrey de Grey, Dr. Oliver Medvedik, MMTP coordinators Steve Hill and Elena Milova, President Keith Comito, and one of the most active contributors Alen Akhabaev. The event was one of the rewards from the MMTP campaign launched on last year.

During the first section the panelists discuss the science and progress in the field, touching upon senescent cell therapy with senolytics, its progress and limitations, stem cells therapies and other promising interventions to slow down and potentially reverse age-related damage to health.

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Jun 15, 2017

Watch as Cannabis(THC) Kills Cancer Cells

Posted by in categories: biotech/medical, education

Cancer…your days are numbered!!!

Here’s why there has never been a human clinical trial conducted on the Cancer-Killing power of Cannabis: IT WORKS! Watch cannabis documentary episode on “Treating Cancer.”

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Jun 15, 2017

LEAF President Keith Comito explains the origin of and why crowdfunding research to extend healthy lifespan is both important and exciting

Posted by in categories: biotech/medical, life extension

You may not be familiar with the work we do at and how we are supporting rejuvenation biotech research using the power of crowdfunding. Here is a short video talking about the importance of supporting breakthrough technology and the work we do at

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Jun 14, 2017

Scientists Reverse DNA Damage in Mice. Human Trials are Next

Posted by in categories: biotech/medical, life extension

Sinclair lab enters human trials for DNA repair this year!

DNA is a critical part of the cell, it is the instruction manual for building cells. Whilst DNA is well protected within the cell nucleus damage does occur, therefore DNA repair is absolutely essential for cell function, cell survival and the prevention of cancer. The good news is cells are able to repair damaged DNA but the bad news is that this ability declines with aging for reasons as yet to be fully understood.

An exciting new study by researchers led by Dr. David Sinclair at Harvard Medical School shows a part of the process that enables cells to repair damaged DNA involving the signalling molecule NAD. This offers insight into how the body repairs DNA and why that repair system declines as we age. Before we get into the new research study let’s take a look at how DNA damage relates to aging and what NAD is.

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Jun 14, 2017

Organ chips get smart and go electric

Posted by in categories: biotech/medical, computing, engineering, health, neuroscience

Organs-on-Chips (Organ Chips) are emerging as powerful tools that allow researchers to study the physiology of human organs and tissues in ways not possible before. By mimicking normal blood flow, the mechanical microenvironment, and how different tissues physically interface with one another in living organs, they offer a more systematic approach to testing drugs than other in vitro methods that ultimately could help to replace animal testing.

As it can take weeks to grow human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended times.

It has been particularly difficult to measure changes in electrical functions of cells grown within Organ Chips that are normally electrically active, such as neuronal cells in the brain or beating heart cells, both during their differentiation and in response to drugs.

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Jun 14, 2017

Reaching a Consensus on Aging Biomarkers

Posted by in categories: biotech/medical, life extension

Whilst looking through recent papers about biomarkers and this recent open access paper crossed my desk. The paper is the latest in a line of top to bottom reviews of aging biomarkers for humans. With companies like Unity Biotechnology and the David Sinclair lab entering human clinical trials later this year for senescent cell removal and DNA repair respectively, the development of effective biomarkers to measure how someone is aging and how therapies effect that are a matter of urgency.

Given that there are various causes of aging and that rejuvenation therapies will generally only target one or two of these processes, the first therapies will likely only be partially effective. The aging processes are all interlinked as well so affecting one may effect others, hence there is a need for a comprehensive panel of biomarkers in order for researchers to prove the efficacy of therapies.

Another thing to consider with a therapy such as senescent cell removal is, whilst you can measure how effective it is at removing senescent cells (to a reasonable degree using β-galactosidase etc…) being able to demonstrate the wider benefits of doing so is trickier. So the challenge here is to find a suitable range of biomarkers that can provide a good level of proof that rejuvenation has occurred when using these therapies. This means various measures of functional age and health are required, and these measures should be something the research community as a whole agree upon as being suitable.

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Jun 14, 2017

Scientists Make Remarkable Progress Towards Curing HIV

Posted by in categories: biotech/medical, sex

A collaborative team of scientists and physicians from the Oxford University, Cambridge University, Imperial College London, University College London and King’s College London have made a remarkable progress towards curing patients with HIV infection.

Of 50 patients taking part in NHS funded revolutionary clinical trial, a 44-year-old British man is the first to complete the trial. He showed no sign of the virus in his blood following treatment.

HIV, the human immunodeficiency virus, is a retrovirus found in body fluids of infected person. These can be semen, vaginal and anal fluids, blood, and breast milk. It can be easily transmitted through unprotected sex or simply sharing infected needles. An infected mother can also transmit HIV to her child during pregnancy, delivery, or breastfeeding.

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Jun 14, 2017

David Wood – We Should Prepare for the Future Now

Posted by in categories: biotech/medical, cryonics, life extension

LEAF caught up with Futurist David Wood at the recent International Longevity and Cryopreservation Summit in Madrid to talk about rejuvenation biotechnology.

We recently attended the International Longevity and Cryopreservation Summit in Madrid. LEAF director Elena Milova caught up with futurist David Wood at the summit to ask him about his work and his views on the development of rejuvenation biotechnology.

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Jun 13, 2017

The human brain sees the world as an 11-dimensional multiverse

Posted by in categories: biotech/medical, neuroscience

New research suggests that the human brain is almost beyond comprehension because it doesn’t process the world in two dimensions or even three. No, the human brain understands the visual world in up to 11 different dimensions.

The astonishing discovery helps explain why even cutting-edge technologies like functional MRIs have such a hard time explaining what is going on inside our noggins. In a functional MRI, brain activity is monitored and represented as a three-dimensional image that changes over time. However, if the brain is actually working in 11 dimensions, looking at a 3D functional MRI and saying that it explains brain activity would be like looking at the shadow of a head of a pin and saying that it explains the entire universe, plus a multitude of other dimensions.

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