Lifeboat Foundation

Dr. Alan Green’s patients travel from around the country to his tiny practice in Queens, N.Y., lured by the prospect of longer lives.

Over the past two years, more than 200 patients have flocked to see Green after learning that two drugs he prescribes could possibly stave off aging. One 95-year-old was so intent on keeping her appointment that she asked her son to drive her from Maryland after a snowstorm had closed the schools.

Green is among a small but growing number of doctors who prescribe drugs “off-label” for their possible anti-aging effects. Metformin is typically prescribed for diabetes, and rapamycin prevents organ rejection after a transplant, but doctors can prescribe drugs off-label for other purposes — in this case, for “aging.”

Continue reading “The surprising way some people are fighting aging” »

A new study in mice finds a compound that boosts the effectiveness of the chemotherapy drug cisplatin and stops cancer cells from becoming resistant to it.

Summary: Extracting nanosized exosomes from bone marrow stem cells and injecting them into mice, researchers reverse symptoms of multiple sclerosis. Source: UC IrvineA nanotechnology treatment.

Survey finds that ‘normal’ human tissues are riddled with mutations.

A groundbreaking new cell reprogramming device can turn existing cells into any other type of cell, repairing tissue and organs in mice.

Future neutrino experiments may provide tomographic scans of Earth’s interior by viewing solar neutrinos that pass through our planet’s layers.

The Sun showers Earth with neutrinos, but this “glow” doesn’t dim when the Sun goes down. At night, solar neutrinos penetrate Earth, impinging detectors from below. Like x rays in a medical scanner, these planet-traversing neutrinos might offer information about the material they pass through. New theoretical calculations show that future experiments, such as the Deep Underground Neutrino Experiment (DUNE), could characterize the different layers inside Earth with neutrino-based tomography.

Researchers have discovered that the human body’s 3 trillion cells aren’t clones of a single DNA sequence, as is widely believed. Instead, the cells of the human body contain a plethora of altered DNA, called mutations. These multiply to produce patches of tissue, called “somatic clones,” inside the ‘normal’ tissue. The scientific term for this phenomenon is mosaicism.

For centuries biologists have identified new species at a painstakingly slow pace, describing specimens’ physical features and other defining traits, and often trying to fit a species into the tree of life before naming and publishing it. Now, they have begun to determine whether a specimen is likely a novel species in hours—and will soon do so at a cost of pennies. It’s a revolution driven by short stretches of DNA—dubbed barcodes in a nod to the familiar product identifiers—that vary just enough to provide species-distinguishing markers, combined with fast, cheap DNA sequencers.

As massive global effort launches, portable DNA sequencers also allow species identification in the field.

Recent research in the field of mind-body medicine shows there’s a lot more to health than what you eat, and most of it has to do with your mind.