Lifeboat Foundation

The Longevity industry will dwarf all other industries in both size and market capitalization and will require unprecedented sophistication in its approach for assessment and forecasting from the start to neutralize challenges and manifest opportunities

The Longevity Industry is not just about biotechnology and biomedicine. Rather, it consists of several distinct segments: Geroscience, Biomedicine, AgeTech and Finance. Despite this seemingly clear market segmentation, many of these sectors intersect with various domains of science and technology, such as advanced biomedicine, preventive medicine, digital health, AI, financial systems, pension systems and government national strategies.

One of the biggest challenges in assessing the Longevity industry is the extreme broadness of the sector. Hundreds of sectors, industries and domains of science and technology must be analyzed in order to obtain a concrete and comprehensive understanding of the dynamics, trends and direction of the industry. This situation is entirely unique to the Longevity industry. Due to this extreme level of complexity, realistic assessment and forecasting is extremely challenging, and the methods currently being applied for assessment of the biotech and biomedical industries are completely inadequate.

Super-charging a treatment for leukemia also makes it effective on solid tumors.

The past decade of Alzheimer’s disease research has been fraught with disappointment.

Years of focus on one hallmark of the disease ultimately resulted in no progress toward treatment or prevention.

But next week, when top scientists gather in Los Angeles at the Alzheimer’s Association International Conference, an annual meeting, many will present research on a different target: inflammation.

A simple cold virus could wipe out tumors in a form of bladder cancer, a small new study suggests.

Though the idea of using viruses to fight cancer isn’t new, this is the first time a cold virus effectively treated an early-stage form of bladder cancer. In one patient, it eliminated a cancerous tumor, the group reported July 4 in the journal Clinical Cancer Research.

A group of researchers conducted an early-stage clinical trial in which they infected 15 bladder cancer patients with coxsackievirus A21, which is one of the viruses that cause the common cold. Coxsackievirus is not a genetically modified virus; it’s “something that occurs in nature,” said senior author Hardev Pandha, a professor of medical oncology at the University of Surrey in England. [Exercise May Reduce the Risk of These 13 Cancers].

https://www.youtube.com/watch?v=of2F3xgImi0

Is comprehensive damage repair feasible? A debate at Undoing Aging 2019 between Vadim Gladyshev, Harvard Medical School and Aubrey de Grey, SENS Research Foundation.

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A 22-year-old woman from the Netherlands who suffers from a chronic bone disorder — which has increased the thickness of her skull from 1.5cm to 5cm, causing reduced eyesight and severe headaches — has had the top section of her skull removed and replaced with a 3D printed implant.

The operation was performed by a team of neurosurgeons at the University Medical Centre Utrecht and the university claims this is this first instance of a successful 3D printed cranium that has not been rejected by the patient.

Those who had adhered to statin treatment vs those who had not were found to have 34% lower all-cause mortality rates. Fewer atherosclerotic cardiovascular disease events were reported in relation to adherence to statins. Irrespective of age and sex, reduced mortality and cardiovascular morbidity may be seen in older adults in relation to adherence to statins.

Internal Medicine Article: Statin use over 65 years of age and all-cause mortality: A 10-year follow-up of 19,518 people.

YaleNew

In a stunning scientific breakthrough, Yale School of Medicine researchers restored brain activity in pigs that had died hours before. The finding could revolutionize the neuroscience field and how scientists conceive the boundaries between life and death.

By circulating a cocktail of cell-rejuvenating compounds throughout the pigs’ brains, the researchers prevented tissue decomposition and restored some cell function. If replicated, their technique could be used as a model for drug testing and has implications for how scientists understand brain plasticity after traumatic events such as strokes.

The drugs we’ve developed to help us deal with chronic pain largely focus on suppressing its symptoms, rather than eliminating its underlying causes. By studying the way pain works in injured fruit flies, scientists have for the first time uncovered evidence that its effects can be long-lasting, something they say opens up new opportunities for more effective treatments in humans.