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5 Most Promising Anti-Aging Compounds (Updated 2022)

Due to last years success, I am back with an updated list of my 5 most promising anti-aging compounds.

There are more than 200 different geroprotective compounds. Some of these are already available as supplements, some are in clinical trials and some have FDA approval. Which are my top 5 that I think i most promising in terms of their anti-aging effects (so focusing more on healthspan than lifespan). And note the use of “promising” — there is still much work to be done to better investigate the long-term safety, dose and timings of different supplements which you should always bear in mind.

Anyway, I made this video more for a bit of fun and to make a longer summary video to pull ideas together from multiple previous videos with some new info too! So hope you like it! And disclaimer — this is not recommendation or health advise — i am not a medical doctor!!

Do my top 5 match yours?

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I have Patreon — https://www.patreon.com/TheSheekeyScienceShow.

Potential new gene editing tools uncovered

Few developments have rocked the biotechnology world or generated as much buzz as the discovery of CRISPR-Cas systems, a breakthrough in gene editing recognized in 2020 with a Nobel Prize. But these systems that naturally occur in bacteria are limited because they can make only small tweaks to genes. In recent years, scientists discovered a different system in bacteria that might lead to even more powerful methods for gene editing, given its unique ability to insert genes or whole sections of DNA in a genome.

New research from The University of Texas at Austin dramatically expands the number of naturally occurring versions of this system, giving researchers a wealth of potential new tools for large-scale gene editing.

Other scientists had identified clusters of genes that use CRISPR to insert themselves into different places in an organism’s genome, dubbed CRISPR-associated transposons (CASTs). Earlier work has shown they can be used to add an entire gene or large DNA sequence to the genome, at least for bacteria.

This New Ultra-Compact Camera Is The Size of a Grain of Salt And Takes Stunning Photos

Scientific ingenuity means cameras keep on getting smaller and smaller, and the latest to appear is not only incredibly tiny – the same size as a grain of salt – it’s also able to produce images of much better quality than a lot of other ultra-compact cameras.

Using a technology known as a metasurface, which is covered with 1.6 million cylindrical posts, the camera is able to capture full-color photos that are as good as images snapped by conventional lenses some half a million times bigger than this particular camera.

And the super-small contraption has the potential to be helpful in a whole range of scenarios, from helping miniature soft robots explore the world, to giving experts a better idea of what’s going on deep inside the human body.

New Synthetic Biomaterial Can Repair Hearts, Muscles, and Vocal Cords

Combining knowledge of chemistry, physics, biology, and engineering, scientists from McGill University develop a biomaterial tough enough to repair the heart, muscles, and vocal cords, representing a major advance in regenerative medicine.

“People recovering from heart damage often face a long and tricky journey. Healing is challenging because of the constant movement tissues must withstand as the heart beats. The same is true for vocal cords. Until now there was no injectable material strong enough for the job,” says Guangyu Bao, a PhD candidate in the Department of Mechanical Engineering at McGill University.

These gorgeous images could transform science education

Science isn’t all lab coats and test tubes. Beautiful visuals can engage people—especially students—and inspire them to learn about science more broadly.

Scientists have often invited the public to see what they see, using everything from engraved woodblocks to electron microscopes to explore the complexity of the scientific enterprise and the beauty of life. Sharing these visions through illustrations, photography, and videos has allowed laypeople to explore a range of discoveries, from new bird species to the inner workings of the human cell.

As a neuroscience and bioscience researcher, I know that scientists are sometimes pigeonholed as white lab coats obsessed with charts and graphs. What that stereotype misses is their passion for science as a mode of discovery. That’s why scientists frequently turn to awe-inducing visualizations as a way to explain the unexplainable.

The BioArt Scientific Image and Video Competition, administered by the Federation of American Societies for Experimental Biology images with the public that are rarely seen outside the laboratory in order to introduce and educate laypeople about the wonder often associated with biological research. BioArt and similar contests reflect the lengthy history of using imagery to elucidate science.

In Photos And Video: Antarctica’s Exclusive Eclipse Of The Sun Attracts Intrepid Travelers —And Humpback Whales

A total solar eclipse occurred early this morning across one of our planet’s most remote and beautiful regions. It was, as always, utterly surreal.

For some, the 1 minute 30 seconds (or so) event at around 07:00 UTC was marred by low and high cloud in the Scotia Sea. There were 14 cruise ships in the 290 miles-wide path of totality, but so far there have been no reports of clear views.

While a view of the Sun’s corona–revealed only for the precious few moments of totality–is the big prize for eclipse-chasers, the immense scale of the event is always incredible to be a part of.

“We wound up much further to the north of where everyone else appeared to go around the South Orkney Islands,” said says Tyler Nordgren, a space artist and former astronomy educator who will be lecturing for Betchart Expeditions on the M/V Hondius. “But in the end, even though we had hints of sunlight at one point, all we experienced was the sudden rush of darkness as the moon’s shadow passed overhead.”

Full Story:

Immune system-stimulating nanoparticle could lead to more powerful vaccines

A common strategy to make vaccines more powerful is to deliver them along with an adjuvant — a compound that stimulates the immune system to produce a stronger response.

Researchers from MIT, the La Jolla Institute for Immunology, and other institutions have now designed a new nanoparticle adjuvant that may be more potent than others now in use. Studies in mice showed that it significantly improved antibody production following vaccination against HIV, diphtheria, and influenza.

“We started looking at this particular formulation and found that it was incredibly potent, better than almost anything else we had tried,” says Darrell Irvine, the Underwood-Prescott Professor with appointments in MIT’s departments of Biological Engineering and Materials Science and Engineering; an associate director of MIT’s Koch Institute for Integrative Cancer Research; and a member of the Ragon Institute of MGH, MIT, and Harvard.

How Many Calories Are Optimal For Health?

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Papers referenced int the video:
Joint distribution of lipoprotein cholesterol classes. The Framingham study.
https://pubmed.ncbi.nlm.nih.gov/6573877/

Long-term coronary heart disease risk associated with very-low-density lipoprotein cholesterol in Chinese: the results of a 15-Year Chinese Multi-Provincial Cohort Study (CMCS)
https://pubmed.ncbi.nlm.nih.gov/20223457/

Red blood cell distribution width and cardiovascular diseases.
https://pubmed.ncbi.nlm.nih.gov/26623117/

Red blood cell distribution width is significantly associated with aging and gender.
https://pubmed.ncbi.nlm.nih.gov/24897405/

Red cell distribution width associations with clinical outcomes: A population-based cohort study.

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