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Aging industry blindspots | S Arrison, 100 Plus Capital, K Pfleger, AgingBiotech.info, M West, AgeX

57:03 “A tool that would be used for millenia.”


Foresight biotech & health extension group sponsored by 100 plus capital.

Accelerator applications are open now: https://foresight.org/biotech-health-extension-program.

Industry blindspots: Unincentivized work that could dramatically advance progress on aging.

SONIA ARRISON, 100 Plus Capital.

Biotech entrepreneur George Church launches gene therapy startup to design safer viral vectors

The adeno-associated viruses often used as vectors to deliver gene therapy can trigger unwanted and sometimes dangerous immune responses. Now, a Harvard University team led by renowned geneticist George Church, Ph.D., has developed a way to “cloak” AAVs from immune surveillance. They’ve spun off Ally Therapeutics to develop it.

Mechanochemical bond scission for the activation of drugs

Stimuli-responsive control of drug activation can mitigate issues caused by poor drug selectivity. Now, it has been shown that mechanical force—induced by ultrasound—can be used to activate drugs in three different systems. This approach has enabled the activation of antibiotics or a cytotoxic anticancer agent from synthetic polymers, polyaptamers and nanoparticle assemblies.

Dr. David Glanzman Ph.D. — UCLA — Studying Cell-Intrinsic Learning And Memory Storage Dynamics

Cell-Intrinsic Learning And Memory Storage Dynamics — Dr. David Glanzman Ph.D., Professor, in the Department Integrative Biology and Physiology, at UCLA College of the Life Sciences.


Dr. David Glanzman is Professor, in the Department Integrative Biology and Physiology, at UCLA College of the Life Sciences, Professor in the Department of Neurobiology in the David Geffen School of Medicine, and Member, Brain Research Institute.

Dr. Glanzman has a B.A. in Psychology from Indiana University Bloomington and a Ph.D. in Psychology from Stanford University.

Dr. Glanzman is interested in the cell biology of learning and memory in simple organisms.

In Dr. Glanzman’s lab research they use two animals, the marine snail Aplysia californica, and the zebrafish (Danio rerio).