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Category: biotech/medical – Page 1,581

Lab-generated sperm created at Israeli university

Researchers built a 3D model and tested it on young mice who were not yet capable of producing sperm – and after 5–7 weeks, sperm cells in the process of developing were discovered in the model, marking the success of the experiment.

“This system may also serve as an innovative platform for examining the effect of drugs and toxins on male fertility” Prof. Mahmoud Huleihel, BGU’s Faculty of Health Sciences

“This study opens up a new horizon in the process of creating sperm cells in a culture,” says study co-author Prof. Mahmoud Huleihel from BGU’s Faculty of Health Sciences. “It enables the implementation of microfluidic-based technologies in future therapeutic strategies for infertile men and in the preservation of fertility for children undergoing aggressive chemotherapy/radiotherapy treatments that may impair their fertility in puberty.”

New type of 3D printing uses sound waves to build up objects

“Ultrasonic frequencies are already being used in destructive procedures like laser ablation of tissues and tumours,” said Prof. Muthukumaran Packirisamy, who led the study along with Dr. Mohsen Habibi and PhD student Shervin Foroughi. “We wanted to use them to create something.”

For instance, utilizing the technique, aircraft mechanics could conceivably 3D-print repairs onto internal components, without opening the plane’s fuselage. It’s even possible that implants could be 3D printed within a patient’s body, without the need for surgery.

Besides the PDMS resin, the scientists have also successfully used DSP to print objects made of ceramic material. They now plan on experimenting with polymer-metal composites, followed by pure metal.

3D printing typically involves depositing layers of molten plastic, laser-melting powdered metal, or using UV light to harden gelatinous resin. A new technique takes yet another approach, however, by utilizing sound waves.

Developed by a team of scientists at Canada’s Concordia University, the technology is known as direct sound printing (DSP).

In the current version of the technique, a transducer is used to send focused pulses of ultrasound through the sides of a chamber, into liquid polydimethylsiloxane (PDMS) resin contained within. Doing so produces ultrasonic fields, which cause rapidly oscillating microscopic bubbles to temporarily form at specific points in the resin.

Continue reading “New type of 3D printing uses sound waves to build up objects” | >

WHO Is The OBSERVER That Holds The Key For OUR YOUTHFULNESS? | Dr David Sinclair Interview Clips

Observer, backup youthful copy, playing the right piano notes, quantum states oh my.

Dr David Sinclair explain about through his lab experiments, why he thinks there is an observer/backup copy for our youthfulness and what are the possible identities he can think of in this clip.

David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.

Dr David Sinclair has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political and benefits of a world in which billions of people can live much longer and much healthier lives.

Dr David Sinclair is the co-founder of several biotechnology companies (Life Biosciences, Sirtris, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others.

Continue reading “WHO Is The OBSERVER That Holds The Key For OUR YOUTHFULNESS? | Dr David Sinclair Interview Clips” | >

Neural ‘Poisonous Flowers’ Could Be The Source of Alzheimer’s Plaque, Says Study

Alzheimer’s disease has long thwarted our best efforts to pinpoint its underlying causes. Now, a new study in mice suggests that ‘poisonous flowers’ bulging with cellular debris could be the root source of one hallmark of the wretched disease and a beautifully sinister sign of a failing waste disposal system inside damaged brain cells.

The study, led by neuroscientist Ju-Hyun Lee of New York University (NYU) Langone, challenges the long-standing idea that the build-up of a protein called amyloid-beta between neurons is a crucial first step in Alzheimer’s disease, the most common form of dementia.

Instead, it suggests that damage to neurons may take root inside cells well before amyloid plaques fully form and clump together in the brain, a finding which could provide new therapeutic possibilities.

This tiny handheld precision 3D scanner is the ultimate reverse-engineering instrument

https://www.kickstarter.com/projects/2125914059/revopoint-mi…m-precison Designers, architects, engineers, we’re all collectively known as creators. The Revopoint MINI handheld 3D scanner just amplifies our creating (or rather re-creating) abilities. Designed to be about the same size as a podcasting microphone (with the tripod and all), Revopoint MINI is an industrial-grade handheld 3D scanner with a staggering precision of 0.02mm. It uses a Class 1 Blue Light that lends it its high accuracy, while still allowing it to be safe on the skin. Just hold it against the object you want to scan and wave it around and like magic, the Revopoint MINI gives you a high-accuracy 3D model, complete with tolerances, textures, and even color information. This makes it perfect for a wide degree of applications, from 3D modeling and animation to medical design, automotive design, jewelry design, even archaeology.

Scientists think they have found a major cure: ‘The first time this has happened in the history of cancer’

New findings were published in the New England Journal of Medicine on Sunday that found all rectal cancer patients given a certain bill were cancer-free.

The New York Times reported the findings, noting that the sample size was incredibly small, with just 18 people but the results were unbelievable.

“I believe this is the first time this has happened in the history of cancer,” said Dr. Luis A. Diaz Jr. of Memorial Sloan Kettering Cancer Center.

Scientists announce a breakthrough in determining life’s origin on Earth—and maybe Mars

Scientists at the Foundation for Applied Molecular Evolution announced today that ribonucleic acid (RNA), an analog of DNA that was likely the first genetic material for life, spontaneously forms on basalt lava glass. Such glass was abundant on Earth 4.35 billion years ago. Similar basalts of this antiquity survive on Mars today.

More information:

Craig A. Jerome et al, Catalytic Synthesis of Polyribonucleic Acid on Prebiotic Rock Glasses, Astrobiology (2022). DOI: 10.1089/ast.2022.

Hyo-Joong Kim et al, Prebiotic stereoselective synthesis of purine and noncanonical pyrimidine nucleotide from nucleobases and phosphorylated carbohydrates, Proceedings of the National Academy of Sciences (2017). DOI: 10.1073/pnas.

Hyo-Joong Kim et al, A Prebiotic Synthesis of Canonical Pyrimidine and Purine Ribonucleotides, Astrobiology (2019). DOI: 10.1089/ast.2018.

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