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Japanese university uses iPS cells in first treatment of spinal cord injury

About 2 million cells are transplanted into each patient in the treatment. They were created from iPS cells stored at Kyoto University in western Japan, according to Keio University.

In the future, the university plans to increase the number of cells to be transplanted in order to enhance the effectiveness of the treatment.

Some 5,000 people sustain spinal cord injuries every year in Japan and the number of people living with spinal cord injuries is said to exceed 150,000.

Humans Might Need Artificial Gravity for Space Travel

Despite the fact that floating around in space looks like a certified blast, it’s not something the human body is optimized for. In order to make these trips possible, scientists are going to have to figure out how to mimic Earth’s gravity in space.
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We evolved with gravity constantly pulling on us at a rate of about 9.8 m/s2, or 1 g. Our bodies are built in a way that takes that into account. Our rigid bones can hold us up, our cardiovascular system can pump blood to and from our extremities, our vestibular system in our ears keeps us balanced, and so on. Our bodies are also good at adapting to our needs, which means when you take gravity away the body starts to change. Bones lose mineral density, hearts weaken, and the vestibular system shuts off because suddenly there is no “up” anymore. So long as the body stays in space these changes aren’t really a problem, but coming back to Earth and readapting to 1 g can be painful and disorienting.

To make the transition to Earth easier, astronauts on the ISS have to spend two and a half hours every day doing aerobic and resistive exercise. It takes a lot of valuable time and still doesn’t prevent all bodily changes, so maybe some sort of artificial gravity could be a better solution. The only practical way to recreate the effects of gravity would be by using centrifugal force, aka spinning. If you’ve ever clung for dear life to one of those whirligigs on a playground you know what I’m talking about. If astronauts could somehow be spun around that might mimic gravity enough to keep their bodies from changing too drastically. There have actually been several proposals on how to leverage centrifugal force, and each of them has its downsides.

One of them is a staple of sci-fi: a spacecraft with a gigantic rotating section. Inside the astronauts would be pushed towards the outermost wall and that would become the “floor”, so to speak, while the rest of the station would remain stationary and in microgravity. But a spacecraft like this would be really complex and expensive to build. Another design is a long spacecraft that twirls like a baton, creating Earth-like acceleration at either end. If the craft were about a kilometer long it would only need to rotate once or twice a minute, but a kilometer-long spacecraft would be about 10 times longer than the ISS and an incredible engineering feat.

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Why does China want to build a kilometre-long spacecraft? And is it even possible?

How This Electricity-Free Fridge Saved An Indian Ceramics Factory | Big Business

In 2001, the founder of Mitticool ceramics learned many of his customers in India don’t have regular access to electricity. So he invented a fridge made out of clay. It keeps food 8 degrees cooler than the outside air, but it doesn’t need any electricity to run. And while other ceramics companies in the region shut down, Mitticool is thriving thanks to the success of the powerless, eco-friendly fridge.

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#BusinessInsider #Ceramics #Mitticool.

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How 15,000 Ceramics Are Made A Day In Gujarat | Big Business.

Pfizer seeks approval for oral COVID-19 pill in Japan

Pfizer Japan Inc. said Friday it has applied to the health ministry for approval of its COVID-19 pill which, if granted, would make it the second oral drug for mild coronavirus cases available in the country.

The new drug application for Paxlovid, a combination of the antiviral drugs nirmatrelvir and ritonavir, comes as Japan is battling its sixth surge of COVID-19 cases amid a spread of the omicron variant, with the country already agreeing to procure enough of the drug for 2 million people.

Dr Tohru Minamino, MD, PhD — Cardiovascular Aging & Targeted Senolytic Bio-Therapies — Juntendo Univ

Cardiovascular Aging & Targeted Senolytic Bio-Therapies — Prof. Dr. Tohru Minamino, MD, PhD, Juntendo University, Japan


Dr. Tohru Minamino is Professor and Chairman of the Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine (https://juntendo-cvbm.com/en/about.html). He also serves as Director of the Cardiovascular Medicine, Juntendo University Hospital. He received his MD from the Chiba University Graduate School of Medicine in 1989 and his PhD from Faculty of Medicine, the University of Tokyo in 1997.

Dr. Minamino is a medical cardiologist and research scientist focusing on molecular mechanisms of aging. He started his major research focusing on cardiovascular aging at Harvard Medical School (1997–2000), and his research interests have currently been growing in the biology of aging including metabolic pathways of longevity and senolysis. He has published more than 100 papers including in Nature, Nature Medicine, Cell, Cell Metabolism, and Lancet.

Dr. Minamino has won several awards including Satoh Memorial Award in Japanese Circulation Society, and Erwin von Bälz Award (1st prize).

New partnership to accelerate microbiome analysis with AI augmentation

“Data science is also absolutely key to our research at the Quadram Institute into the gut microbiome and its influence on human health, all of which is mediated by the complex interactions of micro-organisms, the food we eat, and the environment of the gastro-intestinal tract itself.”

E[datascientist] leverages AI and network science in order to surface scientific connections and explore multi-causal relationships, for example to better understand the microbiome. The platform also improves the digitisation, and reduces the siloisation, of legacy scientific R&D systems, which can be used in tandem with datasets from publicly available databases, all in a standardised format. In this way e[datascientist] supports the entire R&D workflow, accelerating the generation of novel insights and ultimately reducing time to market.

Eagle Genomics plans to continue to be engaged in discussions with a range of other organisations to ensure that its platform continues to become a burgeoning global life sciences knowledge discovery hub.

Rise of the machines: China’s struggling industries embrace automation

The pace of replacing humans with robots in industries across China has been accelerating rapidly in the past couple of years, with observations on the ground suggesting that most industrial robotics and intelligent-manufacturing integrated service companies had at least doubled their annual sales in 2021.


Pandemic-led manufacturing export boom, concerns over China’s rapidly ageing society and a desire to save money have all contributed to the trend of replacing workers with machines.

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