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How Gut Microbe Symbiosis Helps Squirrels Keep Their Muscles During Hibernation

Ground squirrels spend the end of summer gorging on food, preparing for hibernation. They need to store a lot of energy as fat, which becomes their primary fuel source underground in their hibernation burrows all winter long.

While hibernating, ground squirrels enter a state called torpor. Their metabolism drops to as low as just 1 percent of summer levels and their body temperature can plummet to close to freezing. Torpor greatly reduces how much energy the animal needs to stay alive until springtime.

That long fast comes with a downside: no new input of protein, which is crucial to maintain the body’s tissues and organs. This is a particular problem for muscles.

Africa may have reached the pandemic’s holy grail

When the results of his study came in, Kondwani Jambo was stunned.

He’s an immunologist in Malawi. And last year he had set out to determine just how many people in his country had been infected with the coronavirus since the pandemic began.

Jambo, who works for the Malawi-Liverpool-Wellcome Trust Clinical Research Programme, knew the total number of cases was going to be higher than the official numbers. But his study revealed that the scale of spread was beyond anything he had anticipated — with a huge majority of Malawians infected long before the omicron variant emerged. “I was very shocked,” he says.

So to fill in the true picture, Jambo and his collaborators turned to another potential source of information: a repository of blood samples that had been collected from Malawians month after month by the national blood bank. And they checked how many of those samples had antibodies for the coronavirus. Their finding: By the start of Malawi’s third COVID-19 wave with the delta variant last summer, as much as 80% of the population had already been infected with some strain of the coronavirus.


New findings from Malawi suggest the country has entered something akin to the endemic stage of the pandemic — along with many other African nations.

The Generation of Superhumans — Can We Edit Our Genes?

New technologies have considerably improved scientists’ ability to locate the genetic variations that distinguish our DNA from that of other people. In some instances, these genetic differences give rise to diverse superhuman abilities. There is growing interest in identifying genes associated with special abilities, many of which seem to be inherited. Some consider people like Wim Hof a.k.a the iceman known for the Wim Hof method as a person with superhuman abilities.

As for the future, according to prominent scientists within 30 years, it will probably be possible to make essentially any kind of change to any kind of genome.

#superhuman #science #sciencetime.

Sources:
Supergenes — https://arep.med.harvard.edu/gmc/protect.html.

George Church — Genetic Superpowers: Changing Your Genome and Environment, Harvard Medical School.

Can deep sleep help devastating brain disorders? Scientists studying Parkinson’s want to find out

𝙎𝙡𝙚𝙚𝙥 𝙢𝙖𝙮 𝙗𝙚 𝙤𝙣𝙚 𝙤𝙛 𝙩𝙝𝙚 𝙢𝙤𝙨𝙩 𝙥𝙤𝙩𝙚𝙣𝙩 𝙢𝙚𝙙𝙞𝙘𝙞𝙣𝙚𝙨 𝙛𝙤𝙧 𝙩𝙝𝙚 𝙗𝙧𝙖𝙞𝙣, 𝙨𝙘𝙞𝙚𝙣𝙩𝙞𝙨𝙩𝙨 𝙖𝙧𝙚 𝙙𝙞𝙨𝙘𝙤𝙫𝙚𝙧𝙞𝙣𝙜, 𝙖𝙨 𝙩𝙝𝙚𝙮 𝙚𝙭𝙥𝙡𝙤𝙧𝙚 𝙩𝙝𝙚 𝙞𝙣𝙣𝙚𝙧 𝙡𝙖𝙗𝙮𝙧𝙞𝙣𝙩𝙝𝙨 𝙤𝙛 𝙩𝙝𝙚 𝙩𝙝𝙧𝙚𝙚-𝙥𝙤𝙪𝙣𝙙 𝙤𝙧𝙜𝙖𝙣 𝙙𝙪𝙧𝙞𝙣𝙜 𝙙𝙚𝙚𝙥 𝙨𝙡𝙚𝙚𝙥 𝙖𝙣𝙙 𝙙𝙧𝙚𝙖𝙢 𝙘𝙮𝙘𝙡𝙚𝙨 𝙞𝙣 𝙗𝙤𝙩𝙝 𝙝𝙚𝙖𝙡𝙩𝙝 𝙖𝙣𝙙 𝙙𝙞𝙨𝙚𝙖𝙨𝙚.

The Neuro-Network.

𝐂𝐚𝐧 𝐝𝐞𝐞𝐩 𝐬𝐥𝐞𝐞𝐩 𝐡𝐞𝐥𝐩 𝐝𝐞𝐯𝐚𝐬𝐭𝐚𝐭𝐢𝐧𝐠 𝐛𝐫𝐚𝐢𝐧 𝐝𝐢𝐬𝐨𝐫𝐝𝐞𝐫𝐬? 𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭𝐬 𝐬𝐭𝐮𝐝𝐲𝐢𝐧𝐠 𝐏𝐚𝐫𝐤𝐢𝐧𝐬𝐨𝐧’𝐬 𝐰𝐚𝐧𝐭 𝐭𝐨 𝐟𝐢𝐧𝐝 𝐨𝐮𝐭

𝙈𝙚𝙙𝙞𝙘𝙖𝙓𝙥𝙧𝙚𝙨𝙨:


Sleep may be one of the most potent medicines for the brain, scientists are discovering, as they explore the inner labyrinths of the three-pound organ during deep sleep and dream cycles in both health and disease.

New tech could reverse diseases, including IBS and diabetes, using intestinal cells

A newly developed technology platform has the potential to treat diseases like diabetes, IBS, and obesity by using enteroendocrine (EE) cells found in human intestinal cells, according to a recent study. Although enteroendocrine cells make up only about 1% of intestinal cells, they produce around fifteen different hormones that play a role in regulating digestion and metabolic function.

Creating Organoids

The new organoid platform, developed at Boston Children’s Hospital, is meant to pinpoint drugs that can increase the amount of EEs and encourage them to generate more needed hormones. “There’s been interest in exploiting human intestinal stem cells and EE cells to treat disease,” says David Breault, MD, Ph.D. in a statement. Breault is associate chief of the Division of Endocrinology at Boston Children’s. “But the field is still in a nascent stage. This will open new avenues of discovery.”

Indonesia Is Changing Its Capital Because of Jakarta’s Unsolvable Problems

“The main goal is to build a smart new city, a new city that is competitive at the global level, to build a new locomotive for the transformation… toward an Indonesia based on innovation and technology based on a green economy.”

Environmental groups not on board However, not all are on board with Widodo’s new plans. Environmental groups worry that the new city may disturb the orangutans, leopards, and other wildlife that already live there. There is also the fact that the new development would cost a whopping $34 billion, a price much too high to pay during an already costly pandemic.

Full Story:


Pretty soon it won’t just be Indonesia’s Navy submarine that will have disappeared. Its capital city Jakarta is also sinking quickly.

Indonesia is looking to replace its capital city because it is very polluted, congested, susceptible to earthquakes, and quickly sinking, according to the Associated Press. The country now aims to build a more sustainable, cleaner, and resilient capital city.

A smart new city

3 Rejuvenation Strategies For Aging

Blood plasma, cellular reprogramming, endogenous.


You may have heard a lot of talk recently about cellular reprogramming, rejuvenation or even “rejuvenation programming”, but what does that all mean and what are the 3 main strategies that several researchers and companies (maybe Altos Labs) will be further investigating?

Well i discuss in this video.

Find me on Twitter — https://twitter.com/EleanorSheekey.

Support the channel.

Scientists Are Growing Human Hair on Mice to Transplant to Bald People

In order to satiate youth-hungry bald people, scientists are growing human hair cells on mice.

Ernesto Lujan, a biologist and founder of medical startup dNovo, told MIT Technology Review that his company has successfully transplanted human hair stem cells onto a mouse.

The result is a horrifying abomination of all that is good, and proof that science has gone too far.

Hospital seeks emergency approval of Israeli COVID drug for moderate-seriously ill

Safed’s Ziv Medical Center has sent a letter to Health Ministry director Nachman Ash requesting he grant emergency authorization for the anti-COVID drug Amor 18 developed by the Israeli company Amorphical in order to treat patients in moderate to serious condition due to the coronavirus, Channel 2 reported Friday.

In letter to Health Ministry director, Ziv Medical Center points to promising results from Amor 18’s clinical trial, where all patients who received drug went on to recover (drug uses Amorphous Calcium Carbonate: ACC).

Israeli biotech company Amorphical recently published what it says are promising results from the second stage of its Amor 18 clinical study.

-please note: Regeneron helped end the ebola pandemic by ending clinical trials early and getting treatments to patients ASAP.

Clinical trial: https://clinicaltrials.gov/ct2/show/NCT04900337