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Category: biotech/medical – Page 1,324

Paradromics is a company developing brain computer interfaces that will help people with disabilities in communicating again. Their product will be the brain computer interface with the highest data rate ever developed. Will it compete with other companies like Neuralink or Kernel in the race to reading the brain?

0:00 Introduction to Paradromics.
1:45 The Product.
5:57 The Surgery.
7:41 Commercial availability.

Check out also this video on another Neuralink competitor, Kernel: https://youtu.be/DUICwT-fqt0

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Sources:
Official Paradromics website: https://paradromics.com/
Paper — Laser Ablation of the Pia Mater for Insertion of High-Density Microelectrode Arrays in a Translational Sheep Model https://www.biorxiv.org/content/10.1101/2020.08.27.269233v2
Paper — The Argo: A 65,536 channel recording system for high density neural recording in vivo https://www.biorxiv.org/content/10.1101/2020.07.17.209403v1.full.
Paper — The Argo: a high channel count recording system for neural recording in vivo https://iopscience.iop.org/article/10.1088/1741-2552/abd0ce.
Paper — Massively parallel microwire arrays integrated with CMOS chips for neural recording https://advances.sciencemag.org/content/6/12/eaay2789
Towards a High-Resolution, Implantable Neural Interface https://www.darpa.mil/news-events/2017-07-10
Matt Angle with an update from Paradromics and their new Neurotech Pub Podcast https://www.youtube.com/watch?v=oSZGk3Smhsc.
The Data Organ: Paradromics CEO Matt Angle On The Future Of The Brain-Computer Interface https://www.forbes.com/sites/johncumbers/2020/04/19/the-data…80a603d4ed.

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Continue reading “A competitor of Elon Musk and NEURALINK? Let’s take a look at PARADROMICS” | >

http://spie.org/bios.

Boyden’s award-winning research has led to tools that can activate or silence neurons with light, enabling the causal assessment of how specific neurons contribute to normal and pathological brain functions.

Ed Boyden is the founder and principal investigator of the Synthetic Neurobiology Group at Massachusetts Institute of Technology (MIT). The group develops tools for controlling and observing the dynamic circuits of the brain, and uses these neurotechnologies to understand how cognition and emotion arise from brain network operation, as well as to enable systematic repair of intractable brain disorders such as epilepsy, Parkinson’s disease, post-traumatic stress disorder, and chronic pain.

Many disorders of the brain currently are treated with drugs or electrical stimulation. Nearly a quarter of million people have implanted electrical probes in their brains for such stimulation. The problem with this approach is that it targets large areas of the brain instead of the discrete cells or location that cause the disorder. Boyden works on implementing light-stimulated processes in the brain to address these disorders at the cellular level. The method utilizes adeno-associated viruses (AAV) to create light-sensitive centers in the brain which can then be stimulated by light pulses. Very small optical waveguides (fibers) can then be introduced in the brain to stimulate these sites.

Boyden was named to the “Top 35 Innovators Under the Age of 35″ by Technology Review and to the “Top 20 Brains Under Age 40″ by Discover, and has received the NIH Director’s New Innovator Award, the Society for Neuroscience Research Award for Innovation in Neuroscience, and the Paul Allen Distinguished Investigator Award, as well as numerous other recognitions. In early 2011, he was an invited speaker at the renowned TED conference, sharing the bill with a high-powered lineup that included presenters as diverse as Bill Gates and choreographer Julie Taymor.

He has contributed numerous articles to SPIE Proceedings, and was an invited speaker at the Biomedical Optics Hot Topics Session at SPIE Photonics West 2011.

Continue reading “Ed Boyden on Optogenetics —- selective brain stimulation with light” | >

Cancer biologist Yibin Kang has disabled a key cancer gene MTDH in mice and in human tissue. A human treatment will be ready for human trials in a few years.

This could be the key to preventing or stopping cancer metastasis which is the primary cause of death due to cancer.

99% of breast cancer patients survive five years after diagnosis, only 29% do if the cancer has metastasized, according to current numbers from the National Cancer Institute.

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Scientists with the help of next gen Artificial Intelligence managed to create the smallest and most efficient camera in the world. A specialist medical camera that measures just under a nanometer has just entered the Guinness Book of Records. The size of the grain of sand, it is the camera’s tiny sensor that is actually being entered into the world-famous record book, for being the smallest commercially available image sensor.
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TIMESTAMPS:
00:00 A new leap in Material Science.
00:57 How this new technology works.
03:45 Artificial Intelligence and Material Science.
06:00 The Privacy Concerns of Tiny Cameras.
07:45 Last Words.
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#ai #camera #technology

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Let me back up a moment. I recently concurred with megapundit Steven Pinker that over the last two centuries we have achieved material, moral and intellectual progress, which should give us hope that we can achieve still more. I expected, and have gotten, pushback. Pessimists argue that our progress will prove to be ephemeral; that we will inevitably succumb to our own nastiness and stupidity and destroy ourselves.

Maybe, maybe not. Just for the sake of argument, let’s say that within the next century or two we solve our biggest problems, including tyranny, injustice, poverty, pandemics, climate change and war. Let’s say we create a world in which we can do pretty much anything we choose. Many will pursue pleasure, finding ever more exciting ways to enjoy themselves. Others may seek spiritual enlightenment or devote themselves to artistic expression.

No matter what our descendants choose to do, some will surely keep investigating the universe and everything in it, including us. How long can the quest for knowledge continue? Not long, I argued 25 years ago this month in The End of Science, which contends that particle physics, cosmology, neuroscience and other fields are bumping into fundamental limits. I still think I’m right, but I could be wrong. Below I describe the views of three physicists—Freeman Dyson, Roger Penrose and David Deutsch—who hold that knowledge seeking can continue for a long, long time, and possibly forever, even in the face of the heat death of the universe.

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In this episode, I talk to world-renowned biologist David Sinclair about aging and longevity. David rejects the notion that the deterioration of health is a natural part of growing old and asserts that aging is a disease itself that we need to reverse. But how will a reset of our biological clocks affect our interactions, responses to adversity, morality, and how we live our lives? We discuss the ethical implications of limitless lifespans and also touch on the topics of death, evolution, genetics, medicine, and data tracking.

Bio.
Dr. David Sinclair is a professor in the department of genetics and co-director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School and co-founder of the scientific journal Aging. He is best known for his work on understanding why we age and how to slow its effects. In addition to being a co-founder of several biotechnology companies, he’s the author of the book Lifespan: Why We Age – and Why We Don’t Have To. Dr. Sinclair was listed by TIME magazine as one of the “100 most influential people in the world”.

Website: sinclair.hms.harvard.edu.

Twitter: @davidasinclair.

Topics.

00:02:26 David’s “sticky beak” personality.

Continue reading “David Sinclair || Why We Age and Why We Don’t Have To” | >

A silicon device that can change skin tissue into blood vessels and nerve cells has advanced from prototype to standardized fabrication, meaning it can now be made in a consistent, reproducible way. As reported in Nature Protocols, this work, developed by researchers at the Indiana University School of Medicine, takes the device one step closer to potential use as a treatment for people with a variety of health concerns.

The technology, called tissue nanotransfection, is a non-invasive nanochip device that can reprogram tissue function by applying a harmless electric spark to deliver specific genes in a fraction of a second. In laboratory studies, the device successfully converted skin tissue into blood vessels to repair a badly injured leg. The technology is currently being used to reprogram tissue for different kinds of therapies, such as repairing brain damage caused by stroke or preventing and reversing nerve damage caused by diabetes.

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