Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 1,233

Humans are good at looking at images and finding patterns or making comparisons. Look at a collection of dog photos, for example, and you can sort them by color, by ear size, by face shape, and so on. But could you compare them quantitatively? And perhaps more intriguingly, could a machine extract meaningful information from images that humans can’t?

Now a team of Standford University’s Chan Zuckerberg Biohub scientists has developed a machine learning method to quantitatively analyze and compare images—in this case microscopy images of proteins—with no prior knowledge. As reported in Nature Methods, their algorithm, dubbed “cytoself,” provides rich, detailed information on location and function within a cell. This capability could quicken research time for cell biologists and eventually be used to accelerate the process of drug discovery and drug screening.

“This is very exciting—we’re applying AI to a new kind of problem and still recovering everything that humans know, plus more,” said Loic Royer, co-corresponding author of the study. “In the future we could do this for different kinds of images. It opens up a lot of possibilities.”

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In medicine, a prosthesis, or a prosthetic implant, is an artificial device that replaces a missing body part, which may be lost through trauma, disease, or a condition present at birth. A pioneering project to develop advanced pressure sensors for use in robotic systems could transform prosthetics and robotic limbs. The innovative research project aspires to develop sensors that provide enhanced capabilities to robots, helping improve their motor skills and dexterity, through the use of highly accurate pressure sensors that provide haptic feedback and distributed touch.

It is led by the University of the West of Scotland (UWS), Integrated Graphene Ltd, and supported by the Scottish Research Partnership in Engineering (SRPe) and the National Manufacturing Institute for Scotland (NMIS) Industry Doctorate Programme in Advanced Manufacturing. This is not for the first time when the team of highly talented researchers have decided to bring the much needed transformative change in prosthetics and robotic limbs.

The human brain relies on a constant stream of tactile information to carry out basic tasks, like holding a cup of coffee. Yet some of the most advanced motorized limbs — including those controlled solely by a person’s thoughts — don’t provide this sort of feedback. As a result, even state-of-the-art prosthetics can often frustrate their users.

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A newly developed, water-activated disposable paper battery promises to make a big impact on single-use electronics – those temporary gadgets used in medical and industrial fields where electronic waste can quickly start piling up.

The battery that has been demonstrated by researchers is biodegradable, made from sustainable materials, and cheap to put together. What’s more, it can be produced in a variety of shapes and sizes as needed.

To give an idea of the power, a two-cell battery made using the technology was enough to power an LCD alarm clock. While it won’t be charging up your laptop anytime soon, there’s lots of potential for low-powered sensors and trackers.

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‘Tis all in the senses.

On her blog, Lepht Anonym describes herself as “a faceless, genderless British biohacker. It lacks both gods and money and likes people, science, and practical transhumanism.” Anonym practices, sometimes referred to as grinding — a subculture of biohacking — DIY surgery to insert electronic hardware under the skin.

At the Grinderfest in 2019, Anonym inserted a little “pirate box” device in her upper right arm.

The Grindfest\

In conversation with Lepht Anonym, a faceless, genderless British biohacker that has implanted over 50 magnets and chips in her body for sensory ‘kicks’.

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A recent study conducted by researchers from the Universities of Newcastle and Leeds has shown that resistant starch has a preventive effect on various hereditary cancers. The double-blind longitudinal study tracked almost 1,000 patients with Lynch Syndrome, a hereditary condition that raises the risk of several cancer types, for nearly 20 years.

“Reducing a range of cancers by over 60%”

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The subtractive manufacturing process involves etching, drilling, or cutting from a solid board to build the final product. It is ideal for applications using a wide variety of materials and in the PCB fabrication of large-size products. In the additive manufacturing process, a product is developed by adding material one layer at a time and bonding the layers together until the final product is ready. The ability to control material density and the possibility of including intricate features makes this process versatile. It is used in a range of engineering and manufacturing applications, especially in custom manufacturing.

Benefits of 3D printing in medical device manufacturing.

3D printing is economical and offers quick PCB prototyping without the need for complex manufacturing steps. It optimizes the PCB design process by avoiding possible design faults in the initial PCB design stages. 3D printing is easy on flex PCBs and multilayer PCB printing is possible using the latest design software. With the growing manufacturing trends and improving software, 3D printing will be more than a prototyping tool and can be a viable alternative for production parts. 3D printing has been recently used for the end-part manufacturing of several medical devices like hearing aids, dental implants, and more. It is more beneficial for low-volume productions.

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Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance, developed by University of Bristol scientists, is published in Nucleic Acids Research.

In this new study, the international team describe how they created a DNA repair vehicle to genetically fix faulty podocin, a common genetic cause of inheritable Steroid Resistant Nephrotic Syndrome (SRNS).

Podocin is a protein normally located on the surface of specialised kidney cells and is essential for kidney function. Faulty podocin, however, remains stuck inside the cell and never makes it to the surface, terminally damaging the podocytes. Since the disease cannot be cured with medications, gene therapy which repairs the genetic mutations causing the faulty podocin offers hope for patients.

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