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A durable bioadhesive hydrogel-elastomer enables continuous imaging of internal organs and tissues.
Constructing a tiny robot from DNA and using it to study cell processes invisible to the naked eye⊠You would be forgiven for thinking it is science fiction, but it is in fact the subject of serious research by scientists from Inserm, CNRS and UniversitĂ© de Montpellier at the Structural Biology Center in Montpellier[1]. This highly innovative ânano-robotâ should enable closer study of the mechanical forces applied at microscopic levels, which are crucial for many biological and pathological processes. It is described in a new study published in Nature Communications.
Our cells are subject to mechanical forces exerted on a microscopic scale, triggering biological signals essential to many cell processes involved in the normal functioning of our body or in the development of diseases.
For example, the feeling of touch is partly conditional on the application of mechanical forces on specific cell receptors (the discovery of which was this year rewarded by the Nobel Prize in Physiology or Medicine).
A diagnostic technique for the Ebola virus uses a micro-ring resonator and a biomarker to quickly identify the presence of the virus in blood samples.
The World Health Organization has confirmed two cases of the deadly Marburg virus disease in Ghana. Hereâs what to know about the Ebola relative.
Throughout life, cells of the body acquire somatic mutations. In frozen post-mortem human brains, researchers from Yale University have found that somatic, or non-inherited, mutations are considerably more likely to accumulate in roughly 6% of brains, and these âhypermutableâ brains are typically 40 years of age or older.
The behavior, comparable to clonal hematopoiesis in the bone marrow that can result in blood cancer in elderly people, is attributed to cell lines with mutations that outcompete other cell lines.
This is the first large-scale study of somatic mutations in human brains. Scientists were not expecting to find this hypermutability in older populations.
Four billion years ago, the Earth looked very different than it does today, devoid of life and covered by a vast ocean. Over the course of millions of years, in that primordial soup, life emerged. Researchers have long theorized how molecules came together to spark this transition. Now, scientists at Scripps Research have discovered a new set of chemical reactions that use cyanide, ammonia and carbon dioxideâall thought to be common on the early earthâto generate amino acids and nucleic acids, the building blocks of proteins and DNA.
âWeâve come up with a new paradigm to explain this shift from prebiotic to biotic chemistry,â says Ramanarayanan Krishnamurthy, Ph.D., an associate professor of chemistry at Scripps Research, and lead author of the new paper, published July 28, 2022 in the journal Nature Chemistry. âWe think the kind of reactions weâve described are probably what could have happened on early earth.â
In addition to giving researchers insight into the chemistry of the early earth, the newly discovered chemical reactions are also useful in certain manufacturing processes, such as the generation of custom labeled biomolecules from inexpensive starting materials.
Self-organizing lasers could lead to new materials for sensing, computing, light sources, and displays by mimicking features of living systems.
Although many artificial materials have advanced properties, they have a long way to go to combine the versatility and functionality of living materials that can adapt to their situation. For example, in the human body bone and muscle continuously reorganize their structure and composition to better sustain changing weight and level of activity.
Now, scientists have demonstrated the first spontaneously self-organizing laser device, which can reconfigure when conditions change.
