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Researchers have explained how visual cortexes develop uniquely across the brains of different mammalian species. A KAIST research team led by Professor Se-Bum Paik from the Department of Bio and Brain Engineering has identified a single biological factor, the retino-cortical mapping ratio, that predicts distinct cortical organizations across mammalian species.

This new finding has resolved a long-standing puzzle in understanding visual neuroscience regarding the origin of functional architectures in the visual cortex. The study, published in Cell Reports on March 10, demonstrates that the evolutionary variation of biological parameters may induce the development of distinct functional circuits in the visual cortex, even without -specific developmental mechanisms.

In the (V1) of mammals, neural tuning to visual stimulus orientation is organized into one of two distinct topographic patterns across species. While primates have columnar orientation maps, a salt-and-pepper type organization is observed in rodents.

For my presentation at the 7th Eurosymposium on Healthy Aging in Brussels tomorrow, I’ve significantly updated my slides “Solving Aging: Is AI all we need?” — It’s still possible to register and attend remotely today and/or tomorrow.


:The Eurosymposium on Healthy Ageing (EHA) is a unique biennial meeting of scientists working on the biology of ageing.

In vivo imaging of large-scale neuronal activity plays a pivotal role in unraveling the function of the brain’s circuitry. Multiphoton microscopy, a powerful tool for deep-tissue imaging, has received sustained interest in advancing its speed, field of view and imaging depth. However, to avoid thermal damage in scattering biological tissue, field of view decreases exponentially as imaging depth increases. We present a suite of innovations to optimize three-photon microscopy for large field-of-view imaging at depths unreachable by two-photon microscopy. These techniques enable us to image neuronal activities of transgenic animals expressing protein calcium sensors in a ~ 3.5-mm diameter field-of-view with single-cell resolution in the deepest cortical layer of mouse brains.

Forget cold plunges. The new flex could soon be human washing machines.

According to one of Japan’s oldest newspapers, an Osaka-based shower head maker called Science has developed a contraption that’s shaped like a cockpit, fills with water when a bather sits in a seat at its center, and measures the person’s pulse and other biological data via sensors to ensure the temperature is just right. It also “projects images on the inside of [its] transparent cover to help the person feel refreshed,” says the outlet.

Dubbed “Mirai Ningen Sentakuki” (human washing machine of the future), the apparatus might never go on sale. Indeed, for now the company’s plans for it appear limited to an expo in Osaka this April, where up to eight people can experience a 15-minute-long “wash and dry” each day after first booking a reservation.

As artificial intelligence (AI) becomes more common and sophisticated, its effects on human lives and societies raises new questions. A new paper published in The Quarterly Review of Biology posits how these new technologies might affect human evolution.

In “How Might Artificial Intelligence Influence Human Evolution?” author Rob Brooks considers the inevitable but incremental evolutionary consequences of AI’s everyday use and human-AI interactions—without “dramatic but perhaps unlikely events, including possibilities of human annihilation, assimilation, or enslavement.”

In the paper, Brooks considers (“often with considerable speculation”) some possible forms of human-AI interaction and the evolutionary implications of such interactions via natural selection, including forms of selection that resemble the inadvertent and deliberate selection that occurred when humans domesticated crops, livestock, and .

We might like to think of ourselves as autonomous entities but, in reality, we’re more like walking ecosystems, teeming with bacteria, viruses, and other microbes. It turns out that differences in these microbes might be as crucial to evolution and natural variation as genetic mutations are.

This novel perspective was discussed in a recent publication by Seth Bordenstein, director of Penn State’s One Health Microbiome Center, who is a professor of biology and entomology and holds the Dorothy Foehr Huck and J. Lloyd Huck Endowed Chair in Microbiome Sciences.

He, along with 21 colleagues from around the globe, collectively known as the Holobiont Biology Network, propose that understanding the relationships between microbes and their hosts will lead to a more profound understanding of biological variation.

Step Into the Future with The Cybernetic Singularity: The Syntellect Emergence 🎧 The groundbreaking third volume of The Cybernetic Theory of Mind series by Alex M Vikoulov is now available as an audiobook!


Ecstadelic Media Group releases a new non-fiction audiobook The Cybernetic Singularity: The Syntellect Emergence, in addition to a previously published Kindle eBook, part of The Cybernetic Theory of Mind series. Written by Alex M. Vikoulov; Narrated by Virtual Voice; Foreword by Antonin Tuynman, PhD; Format: Audible audiobook (Press Release, Burlingame, CA, USA, November 16, 2024 09.23 AM PST)

The Cybernetic Singularity: The Syntellect Emergence is a visionary exploration of humanity’s impending transition into a post-biological state of existence, where artificial intelligence, advanced cybernetics, and collective intelligence converge to form a unified Global Mind. As the third installment in The Cybernetic Theory of Mind series, this book delves into the transformative potential of AI and the emergence of hyperconnected “infomorphs” — substrate-independent minds transcending biological limitations. It examines the profound philosophical, technological, and existential implications of this evolutionary leap, which may redefine what it means to be human. The book also introduces key concepts like Cybernetic Immortality and Experiential Realism, suggesting how we might engineer a future of infinite creativity and bliss.