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The effort is part of a $45 million program across all the branches of the armed forces to figure out military applications for genetic engineering.
Whether we will ever find a way to overcome the physiological trade offs that hold back immortality, or whether we will really be able to replicate human consciousness in a computer are questions too difficult for us yet to answer. But are those leading the charge against death at least inspiring us to lead healthy lives, or are they simply rallying against an inevitable fate?
Long read: How nature is fighting our attempts to use biohacking to live forever.
The question and answer interview of He Jianku conference presentation has the most interesting parts of this debate about human gene editing of embryos. The interview starts at about 1 hour and 28 minutes of the record. The formal presentation showed that the scientist He has taken appropriate scientific care to perform the work. He took care to make sure it was on target and was successful. He took care to make sure there were no unintended off-target side-effects.
* the parents (father HIV positive) made a choice to use the edited embryos versus unedited * the CRISPR vector used to make the change. Appears to be the kind that can be ordered for about $100. There have been adult people who have self-experimented with mail order gene editing kits * the conference interviewer asked about whether He Jianku was aware of a few other research papers. Some paper suggests that the gene CCR5 could cause increased susceptibility to flu and another suggests a tiny increase in cognitive effect.
Intelligence is controlled by many thousands of genes.
For at least the last 10 million years every yeast cell of the sort used to make beer or bread has had 16 chromosomes. But nowâthanks to CRISPR technology and some DNA tinkerers in Chinaâthere are living yeast with just one.
Genome organizer: We humans have our genes arranged on 46 chromosomes, yeast use 16, and thereâs even a fern plant with 1260 of them. Thatâs just the way it is. And no one is quite sure why.
The big one: Do we really need so many chromosomes? Thatâs what Zhogjun Qin and colleagues at the Key Laboratory of Synthetic Biology in Shanghai wanted to know.
Questions have been raised recently regarding Jeanne Calmentâs record as the oldest recorded human.
If you open an article dedicated to supercentenarians, it is very likely that at its very beginning, you will see the name of Jeanne Calment, the oldest known person in the world, who is believed to have lived for up to 122 years. Jeanne is not merely a unique phenomenon from the point of view of statistics; over the years, she became a symbol of extraordinary human capacities.
For a person who sticks to a healthy lifestyle or even engages in biohacking in order to live longer, Jeanneâs record is a teasing goal to achieve and surpass; however, to the researchers of aging, this extremely rare event is rather a reason for curiosity â and skepticism.
Analyst Salveen Richter and colleagues laid it out:
The potential to deliver âone shot curesâ is one of the most attractive aspects of gene therapy, genetically engineered cell therapy, and gene editing. However, such treatments offer a very different outlook with regard to recurring revenue versus chronic therapies⊠While this proposition carries tremendous value for patients and society, it could represent a challenge for genome medicine developers looking for sustained cash flow.
For a real-world example, they pointed to Gilead Sciences, which markets treatments for hepatitis C that have cure rates exceeding 90 percent. In 2015, the companyâs hepatitis C treatment sales peaked at $12.5 billion. But as more people were cured and there were fewer infected individuals to spread the disease, sales began to languish. Goldman Sachs analysts estimate that the treatments will bring in less than $4 billion this year.
The Pentagon is also looking at living camouflage, self-healing paint, and a variety of other applications of engineered organisms, but the basic science remains a challenge.
How do you detect submarines in an expanse as large as the ocean? The U.S. military hopes that common marine microorganisms might be genetically engineered into living tripwires to signal the passage of enemy subs, underwater vessels, or even divers.
Itâs one of many potential military applications for so-called engineered organisms, a field that promises living camouflage that reacts to its surroundings to better avoid detection, new drugs and medicines to help deployed forces survive in harsh conditions, and more. But the research is in its very early stages, military officials said.