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UCLA scientists develop offtheshelf immunotherapy for ovarian cancer

When the team tested the novel CAR-NKT therapy on 35 ovarian patient-derived tumor samples, the results were striking. The CAR-NKT cells successfully killed ovarian cancer cells in every single sample — including samples from both newly diagnosed patients and patients whose cancers had recurred after chemotherapy.

“Combating this high rate of recurrence in ovarian cancer is my career mission,” said co-senior author Memarzadeh, a professor of obstetrics and gynecology and a member of the UCLA Broad Stem Cell Research Center and the UCLA Health Jonsson Comprehensive Cancer Center. “When I see these results, I know we’re getting closer to offering patients like mine a more effective and permanent solution.”

Stroke Severity and Functional Benefit of Thrombectomy in Acute M2 Middle Cerebral Artery OcclusionA Multicenter Cohort Study

Background and ObjectivesRecent randomized trials reported no overall functional benefit of endovascular treatment (EVT) for distal medium-vessel occlusion (DMVO) and did not identify consistent effect modifiers to guide patient selection. Consequently,…

Artificial Intelligence Trends That Will Change Everything

*Discover the biggest Artificial Intelligence trends that will reshape the world over the next decade.*

AI is evolving faster than ever. From autonomous AI agents and humanoid robots to AI-generated video, multimodal intelligence, scientific breakthroughs, and personalized software, the next wave of artificial intelligence is already transforming the way we work, create, and live.

In this video, we’ll explore the most important AI trends that could define the future of technology—and why the biggest AI revolution may already be happening around us.

Chapters:
00:00 The Future of Artificial Intelligence.
00:48 Special Thanks to Our Members.
01:17 AI Agents.
03:01 AI Memory.
04:55 Multimodal AI
06:40 AI Robots.
08:21 Personalized AI
09:41 AI-Generated Video.
11:25 AI in Scientific Discovery.
12:54 Small AI Models.
14:07 The Future of Search.
15:24 Human + AI
16:32 The Invisible AI Future.

If you enjoy content about artificial intelligence, future technology, robotics, automation, and emerging innovations, subscribe to *FutureLens* and join us as we explore the technologies shaping tomorrow.

👍 Like the video if you found it valuable.

Most Of The Universe Is Missing And We Don’t Know Why

Everything you see, touch and are built from is a minority of what the universe is actually made of, and the closer physics looks at the rest, the less the picture holds together. Over the next 3 hours, we move outwards through that problem: from the 85 per cent of matter that is invisible, to the visible matter whose textbook description is admittedly unfinished, to a dimension of space that scientists are now building by hand in a lab, and finally to the question of whether we can ever truly know what reality is made of at all.

Watch our interview with Dark Energy Researcher, Tessa Baker: • What If Dark Energy Comes From Space-Time…

00:00:00 Intro.
00:01:39 We May Be Wrong About Dark Matter.
00:31:38 Frank Close: We Were Wrong About Matter.
01:39:09 Scientists Build A Window Into The Fourth Dimension.
02:01:37 Sean Carroll: We May Never Understand Reality.

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Sugarcoated nanoparticles show promise for treating most aggressive form of brain cancer

Sugar-coated nanoparticles show promise against glioblastoma.

Researchers have developed mannose-coated lipid nanoparticles capable of crossing the blood-brain barrier and delivering therapeutic PTEN mRNA directly to glioblastoma cells, one of the deadliest forms of brain cancer.

Glioblastoma cells have an exceptionally high demand for glucose. By coating the nanoparticles with a sugar molecule called mannose, the researchers took advantage of this metabolic feature, allowing the particles to enter the brain more efficiently and accumulate within tumors.

Once inside the cancer cells, the nanoparticles restored production of PTEN, a critical tumor-suppressor protein that is frequently lost or dysfunctional in glioblastoma. In mouse models, this approach significantly slowed tumor growth, increased median survival by approximately 50%, and showed no measurable toxicity in major organs.

Although these findings are still preclinical and have not yet been tested in humans, they represent an exciting advance in overcoming one of neuro-oncology’s greatest challenges: safely delivering targeted therapies across the blood-brain barrier.


PORTLAND, Ore. – Researchers at Oregon State University have potentially found a new way to treat the most aggressive form of brain cancer, glioblastoma, whose two-year survival rate is less than 30%.

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