Negative perceptions of mental illness and other health issues subtly shape outputs from large language models
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The S1–insula Circuit Differentially Modulates Alcohol Drinking and Aversive Behavior in Mice
Sensory processing assigns salience to environmental and internal stimuli, shaping behavior through learned associations. In alcohol use disorder (AUD), sensory cue processing is dysregulated, driving problematic drinking patterns and hyperkatifeia in abstinence. While visual, olfactory, and taste cues are known to influence AUD progression, the neurocircuit mechanisms that regulate sensory information in addiction remain poorly understood. The primary somatosensory cortex (S1) encodes tactile, thermal, proprioceptive, and nociceptive inputs and projects to higher-order regions involved in motor and emotional processing. One such target is the insula, a hub for interoceptive integration and affective regulation. We previously identified that insula neurons receiving S1 projections in turn extend into the extended amygdala, implicating this projection in emotional processing.
Why Scientists Think This Is Our Strongest Evidence of Aliens
Did we find evidence of aliens in old astronomical records?
We might not be alone in the Universe. While combing through data from 1949, scientists spotted something impossible: strange, vanishing lights. They look exactly like satellites, but were documented decades before humanity ever launched anything into space. What could they be? Could this be evidence of advanced alien technology?
0:00 Evidence of Aliens?
1:18 Nuremberg Sighting 1561
3:45 Verifying Claims.
4:38 Vanishing Objects.
7:08 Is There Another Explanation?
8:31 Are They Real?
10:45 UAP and Nukes.
13:38 Another Explanation?
16:46 Academic Debate.
18:17 Is It Conclusive?
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We FINALLY Know What Happened Before the Big Bang
Have you ever wondered what existed before the Big Bang? For decades, scientists believed that this question had no answer. But new ideas in cosmology and theoretical physics are challenging that assumption.
In this video, we explore some of the most fascinating scientific theories about what may have happened before the birth of our universe. From quantum gravity and cosmic bounces to eternal inflation, multiverse models, and the possibility that our universe emerged from a previous cosmic cycle, these concepts push the boundaries of modern science.
Could time itself have existed before the Big Bang? Was our universe born from the collapse of another? Or is the Big Bang not the true beginning after all?
Join us as we dive into the latest research, thought-provoking hypotheses, and the biggest unanswered questions about the origin of reality.
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#BigBang #Universe #Cosmology #Space #Astronomy #Physics #Science #BlackHoles #Multiverse #JWST
Why Advanced Aliens Probably Don’t Build Dyson Spheres
🫣🤫🤔 Let’s face it: we’re still a Type 0 civilization on the Kardashev Scale… though, to be honest, we’re much closer to the Kardashian Scale 😁 endless entertainment, constant distractions, and celebrity obsession. 🙈🙉🙊 A true Type I civilization would be focused on mastering energy, advancing science, and solving humanity’s biggest challenges. We’ve still got a long way to go! While most people’s main concerns revolve around material comfort, entertainment, and instant gratification, who truly cares about the fate of the most vulnerable? About social exclusion? Inequality? The pollution and destruction of our environment? Who cares about the massive extinction of million of species now underway? Who cares about sustainable development and peace for everyone? A true Type I civilization would be collectively focused on optimizing how it functions and shaping a better future for everyone. We’re still very, very far from that.
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Hello and welcome! My name is Anton and in this video, we will talk about an interesting study on the Fermi paradox, type II civilizations and…bitcoin?
Links:
https://arxiv.org/pdf/2604.23026
https://arxiv.org/pdf/2510.03249
https://arxiv.org/pdf/2604.17516
#fermiparadox #bitcoin #science.
0:00 How we measure alien civilizations.
2:00 Kardashev scale conundrum.
3:25 New model using bitcoin and artificial intelligence.
4:08 Why bitcoin? The Karnac unit.
5:50 Energy required to change a unit of information — Landauer limit.
8:00 New definition for Type 2 civilization.
8:45 AI demand is changing energy consumption.
10:20 Energy limit speculations.
11:40 The great filter hypothesis.
12:30 The crossroads for humanity — conclusions.
Enjoy and please subscribe.
RNA-binding protein diversity and NLS arginines regulate FUS mixing in mRNA-rich compartments
Valenti et al. used the MT bench assay to quantify FUS homotypic/heterotypic interactions in compartments of heterogeneous compositions in cells. They showed that FUS heterotypic interactions with other RBPs, orchestrated by its disease-related NLS, prevent FUS phase separation independently from nuclear transporters.
Engineers create 3D-printed robotic fish that swim, play and recharge themselves through automated charging systems. Here’s all you need to know
Engineers have developed robotic fish that mimic real aquatic life, offering an aquarium experience without the upkeep. These miniature submarines, powered by Arduino and guided by an overhead camera and Raspberry Pi, autonomously navigate, interact, and even return to a wireless charging station. This innovation promises a maintenance-free aquatic display, blending technology with the tranquility of nature for a futuristic aquarium.
