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Researchers used a refined method of ancestry analysis utilizing ancient DNA. This study represents a significant advancement in our understanding of historical population movements.

Researchers can trace human migration through DNA changes, but it’s challenging when historical groups are genetically similar.

Why the kinship between artificial intelligence and the human mind is terrifying.

https://80000hours.org/fireship.

Take a look at 13 trends in technology that will affect programmers and software engineers in the year 2025.

Continue reading “Get the free 80,000 hours career guide” »

In the following link you will find the six most outstanding articles/videos published during the month of December on the website “El Radar del Rejuvenecimiento”

[ https://mailsystem.es/campaign-content/50033](https://mailsystem.es/campaign-content/50033 news/videos are all from reputable scientific sources and almost always published in English, but each of them includes a summary in Spanish.

As the calendar flips to the second quarter of the century, conversations about the transformative potential of Artificial Intelligence (AI) are reaching a fever pitch.

Continue reading “Understanding And Preparing For The Seven Levels Of AI Agents” »

Meanwhile, scientists dug into how psychedelics and MDMA fight off depression and post-traumatic stress disorders. The year was a relative setback for the psychedelic renaissance, with the FDA rejecting MDMA therapy. But the field is still gaining recognition for its therapeutic potential.

Then there’s lenacapavir, a shot that protects people from HIV. Named “breakthrough of the year” by Science, the shot completely protected African teenage girls and women against HIV infection. Another trial supported the results, showing the drug protected people who have sex with men at nearly 100 percent efficacy. The success stems from a new understanding of the protein “capsule” guarding the virus’ genetic material. Many other viruses have a similar makeup—meaning the strategy could help researchers design new drugs to fight them off too.

So, what’s poised to take the leap from breakthrough to clinical approval in 2025? Here’s what to expect in the year ahead.

UC Riverside scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules.

Since the molecules scientists want to detect—generally certain DNA or protein molecules—are roughly one-billionth of a meter wide, the electrical signals they produce are very small and require specialized detection instruments.

“Right now, you need millions of molecules to detect diseases. We’re showing that it’s possible to get useful data from just a single molecule,” said Kevin Freedman, assistant professor of bioengineering at UCR and lead author of a paper about the tool appearing in Nature Nanotechnology. “This level of sensitivity could make a real difference in disease diagnostics.”

Researchers at the Allen Institute have identified a specific brain region in mice where aging triggers significant changes in numerous cell types. The study also pinpointed which cell types undergo the most profound transformations.

This new information, published in the journal Nature, points toward potential approaches for slowing or controlling the aging process in the brain.

The research was focused on numerous glial cell types – the brain’s “support cells” – that demonstrated considerable shifts in gene activity with age. Among the cells most affected were microglia, border-associated macrophages, oligodendrocytes, tanycytes, and ependymal cells.

Although this stem cell model of a notochord is a simple structure, it could help researchers study spine-related birth defects.