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In the over two-decades-long search for dark matter, scientists so far have come up short. In recent years though, construction of new experiments and upgrades to already existing detectors are giving new hope that we’re closer than ever to understanding dark matter.

One of those new efforts is SABRE, an international collaboration that will house multiple detectors working in tandem in the southern and northern hemispheres: two at Italy’s Gran Sasso National Laboratory, and another at an underground lab in an Australian gold mine.

In episode two of The Most Unknown, Motherboard travels to Gran Sasso National Laboratory with physicist Davide D’Angelo and geomicrobiologist Jennifer Macalady to get an early look at SABRE’s latest phase of development.

Read more about The Most Unknown here: https://vice.video/2CQcMZw

The ancient Aztecs first picked the spot. They built their city atop the huge lakes that filled this valley, leaving the natural freshwater supply intact around them. The city flooded back then too, but the Aztecs, probably the last civilization to properly manage this watershed, built a system of dikes to control the problem.

The “historic mistake” kicked in around the 1600s, when Hernándo Cortés and his band of conquerors arrived. To make room for their expanding empire, over a few hundred years, they slowly but surely drained all the valley’s lakes.

By the 20th century, long after Mexico’s independence from Spain, the fresh surface water was mostly gone and the hunt for new sources had taken over. Hundreds of miles of pipes now bring in about 30 percent of the city’s water needs from faraway rivers and lakes. The rest comes from the valley’s vast underground aquifer.

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(HealthDay)—The ancient practice of tai chi may beat strength training and aerobics for preventing falls among seniors, a new trial shows.

A modified senior-centered tai chi program reduced falls nearly a third better in a head-to-head comparison with an exercise regimen that combined aerobics, strength training and balance drills, the researchers reported.

“This tai chi program better addressed the deficits that were contributing to fall risk,” said senior researcher Kerri Winters-Stone, a professor with the Oregon Health & Science University School of Nursing.

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Alzheimer’s disease (AD) is a neurodegenerative disease with characterization of deficits in progressive memory loss, cognitive and behaviour functions. Mild cognitive impairment (MCI) is a predromal stage of AD, displaying cognitive deficit but neither marked functional impairment nor satisfying established clinical criteria for dementia or probable AD. However, not all MCI patients may eventually progress to AD (progressive MCI, pMCI)https://doi.org/10.1016/j.nicl.2013.10.

(2014)." href="https://www.nature.com/articles/s41598-018-31794-8#ref-CR2" id="ref-link-section-d1856e5935"]2, and some remain unchanged (stable MCI, sMCI), or are recovered from. Therefore, differential diagnosis of MCI types and earlier diagnosis of AD and prediction of disease evolution are difficult

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