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Purdue University researchers have developed a new flexible and translucent base for silicon nanoneedle patches to deliver exact doses of biomolecules directly into cells and expand observational opportunities.

“This means that eight or nine nanoneedles can be injected into a single cell without significantly damaging a cell. So we can use these nanoneedles to deliver biomolecules into cells or even tissues with minimal invasiveness,” said Chi Hwan Lee, an assistant professor in Purdue University’s Weldon School of Biomedical Engineering and School of Mechanical Engineering.

A surgeon performs surgery on the back of a hand of a patient who has melanoma. Purdue researchers are developing a new flexible and translucent base for silicon patches to deliver exact doses of biomolecules directly into cells and expand observational opportunities. The researchers say skin cancer could be one of the applications for the patches.

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Anarchy AI ✌️😆


There’s a big new feature for iPhone experts this year: It’s an app called Shortcuts, and with a little bit of logic and know-how, you can stitch together several apps and create a script that can be activated by pressing a button or using Siri.

Some early uses are predictable, like saving Instagram photos, sharing the song you’re listening to, or creating a morning routine that activates your lights and plays a song.

But Robert Petersen of Arizona has developed a more serious shortcut: It’s called Police, and it monitors police interactions so you have a record of what happened.

Researchers at the Center for Quantum Nanoscience (QNS) within the Institute for Basic Science (IBS) achieved a major breakthrough in shielding the quantum properties of single atoms on a surface. The scientists used the magnetism of single atoms, known as spin, as a basic building block for quantum information processing. The researchers could show that by packing two atoms closely together they could protect their fragile quantum properties much better than for just one atom.

The spin is a fundamental mechanical object and governs magnetic properties of materials. In a classical picture, the spin often can be considered like the needle of a compass. The north or south poles of the needle, for example, can represent spin up or down. However, according to the laws of quantum mechanics, the spin can also point in both directions at the same time. This superposition state is very fragile since the interaction of the spin with the local environment causes dephasing of the superposition. Understanding the dephasing mechanism and enhancing the quantum coherence are one of the key ingredients toward spin-based quantum information processing.

In this study, published in the journal Science Advances in November 9, 2018, QNS scientists tried to suppress the decoherence of single by assembling them closely together. The spins, for which they used single titanium atoms, were studied by using a sharp metal tip of a scanning tunneling microscope and the atoms’ were detected using . The researchers found that by bringing the atoms very close together (1 million times closer than a millimeter), they could protect the superposition of these two magnetically coupled atoms 20 times longer compared to an individual atom.

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Today, we want to highlight a recent, small-scale study looking at NAD+ and how it declines with age in the plasma.

The researchers looked at various NAD+ metabolites across age groups and found that the amounts of some of them, particularly NAD+ itself, are significantly smaller in older people than younger ones [1]. This is likely due to an age-related imbalance between the cellular machinery that consumes NAD+ and the machinery that produces it, and this imbalance leads to the lower levels observed. However, it remains unclear if the resulting decline of NAD+ is due to an increase in consumption or a decrease of production.

Other factors may also serve to reduce the amount of NAD+ in plasma, such as inflammatory signaling molecules and oxidative damage to the NAD+ molecules. The researchers also discuss the role of CD38, a major reason why NAD+ declines as we get older and how inhibiting it may be a potential way to boost NAD+.

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Researchers at Umeå university in Sweden have published a new study showing that the gut bacteria can carry information of past experiences of an altered environment from parents to offspring. Eggs and sperm are not the only information carriers from one generation to the next.

Eggs and transmit genetic from one generation to the next. The genetic information contains the blueprint for how to assemble a functional offspring. Most of this information is hardcoded in DNA and cannot be altered by experiences such as changes to the environment.

However, in the last decades, it has been shown that some effects of various lifestyles can be transmitted from to offspring through both the egg and the sperm. This study shows for the first time that also the , which are in general also transmitted from parents to offspring, are capable of transmitting information about what environment the parents were exposed to, to the offspring.

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