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Mark Zuckerberg and his pediatrician wife Priscilla Chan have sold close to 30 million shares of Facebook to fund an ambitious biomedical research project, called the Chan Zuckerberg Initiative (CZI), with a goal of curing all disease within a generation. A less publicized component of that US$5 billion program includes work on brain-machine interfaces, devices that essentially translate thoughts into commands.

From a report: One recent project is a wireless brain implant that can record, stimulate and disrupt the movement of a monkey in real time. In a paper published in the highly cited scientific journal Nature on Monday, researchers detail a wireless brain device implanted in a primate that records, stimulates, and modifies its brain activity in real time, sensing a normal movement and stopping it immediately. Those researchers are part of the Chan Zuckerberg Biohub, a non-profit medical research group within the CZI. Scientists refer to the interference as “therapy” because it is designed to be used to treat diseases like epilepsy or Parkinson’s by stopping a seizure or other disruptive motion just as it starts.

“Our device is able to monitor the primate’s brain while it’s providing the therapy so you know exactly what’s happening,” Rikky Muller, a co-author of the new study, told Business Insider. A professor of computer science and engineering at the University of California, Berkeley, Muller is also a Biohub investigator. The applications of brain-machine interfaces are far-reaching: while some researchers focus on using them to help assist people with spinal cord injuries or other illnesses that affect movement, others aim to see them transform how everyone interacts with laptops and smartphones. Both a division at Facebook formerly called Building 8 as well as an Elon Musk-founded company called Neuralink have said they are working on the latter.

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A Cafe in Tokyo uses an all-robot staff, though some of its employees that control these servers do so remotely, under special circumstances.

As reported by NextShark, these employees have debilitating conditions like ALS and similar spinal chord injuries, and operate the robot servers from home. They operate an OriHime-D: a 4-foot-tall robot that moves, handles objects, and communicates with patrons at Tokyo’s Cafe DAWN (Diverse Avatar Working Network). Cafe DAWN is intended to resemble the robot-centric cafe featured in the 2008 anime Time of Eve.

The technology is facilitated by Ory, an institute that is looking to solve issues of social and physical isolation by using technological advances along with human interaction.

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Here, we will first summarize the experimental achievements over the last 7 years in cell and animal rejuvenation. Then, a comparison will be made between the principles of the cumulative DNA damage theory of aging and the basic facts underlying the epigenetic model of aging, including Horvath’s epigenetic clock. The third part will apply both models to two natural processes, namely, the setting of the aging clock in the mammalian zygote and the changes in the aging clock along successive generations in mammals. The first study demonstrating that skin fibroblasts from healthy centenarians can be rejuvenated by cell reprogramming was published in 2011 and will be discussed in some detail. Other cell rejuvenation studies in old humans and rodents published afterwards will be very briefly mentioned. The only in vivo study reporting that a number of organs of old progeric mice can be rejuvenated by cyclic partial reprogramming will also be described in some detail. The cumulative DNA damage theory of aging postulates that as an animal ages, toxic reactive oxygen species generated as byproducts of the mitochondria during respiration induce a random and progressive damage in genes thus leading cells to a progressive functional decline. The epigenetic model of aging postulates that there are epigenetic marks of aging that increase with age, leading to a progressive derepression of DNA which in turn causes deregulated expression of genes that disrupt cell function. The cumulative DNA damage model of aging fails to explain the resetting of the aging clock at the time of conception as well as the continued vitality of species as millenia go by. In contrast, the epigenetic model of aging straightforwardly explains both biologic phenomena. A plausible initial application of rejuvenation in vivo would be preventing adult individuals from aging thus eliminating a major risk factor for end of life pathologies. Further, it may allow the gradual achievement of whole body rejuvenation.

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The tech-savvy Black Mirror audience is a natural fit since, as Engelbrecht put it, they tend to be “a little more experimental and willing to be out there.” But it was the mind of Brooker and the potential for what he could create that made Netflix want to go all in. In order to fully execute Brooker’s vision, Netflix created new technology, including “state tracking” to remember the choices viewers make over the course of the story. That tech is what allows for the unique experience for each viewer. Choices made earlier in the episode impact scenes and storylines as the viewer goes in ways that can be subtle (like an advertisement for the cereal that was picked) or very impactful, even resulting in which endings a viewer can unlock.


Netflix released its first interactive experience for adults with ‘Black Mirror: Bandersnatch’ on Dec. 28. The teams behind the immersive film, which debuts first-of-its-kind technology, tell The Hollywood Reporter how to be an active player in Charlie Brooker’s story.

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I owe Jack Shaw a favor. It’s one of those, “This one time in Cambodia…” type of favors. We won’t speak of it beyond perhaps a nod and wink. It’s not written down anywhere; the details of such are so vague as to be almost non existent, while encompassing the known universe. It expires upon death, of the sun; and can be redeemed whenever and by another person who need only walk up to me and say, “Jack Shaw sent me. He says to tell you ________”. And tada, that favor has been redeemed for value.

Jack would call this favor a “marker.” It’s more valuable than your house, the Empire State Building & 100k Bitcoins combined. It can even be redeemed for something even more precious, my time or an opportunity or access to my network. You know, those things that money can’t buy. Well, you can lease my time from time to time.

Favors, markers and promises are humanities’ first virtual currencies.

They’ve gone digital recently, as Jack might redeem his marker via a WhatsApp or WeChat text message.

Favors and promises aren’t financial obligations per-say. They’re moral debts that can be redeemed for things of intrinsic, monetary, social and/or actual value. Now, here is where things get a little weird. The thing about “money” is that it doesn’t have any value. It’s actually a reflection of a moral debt. Hence why the US dollar is backed by the “Full Faith and Credit of the US Government” and not say, gold or wheat. You believe…that people will feel obligated to pay taxes and in turn the government will collect these social obligations (aka favors) for the good and benefit of The People. This moral obligation is part of that “Debt to Society” you’ve heard so much about, are obligated to pay, but don’t recall actually signing up for.

Long ago, these virtual currencies of favors, promises, social obligations and credits were turned into what we now regard as money. Not because paper money or coins had or have any intrinsic value, but because for trade beyond one’s family or clan, it’s easier to convey/store and document the value of Sam owing you two chickens, using cash as that documentation (or store of value). As you extended to him a two chicken line of credit.

“Credit” is just another favor or marker with terms.

Coins and “Banknotes” (because people wrote down how much credit they gave you) were just the earliest form of noting and coming to consensus on how to document these virtual currencies of favors, markers, promises and credit.

Overtime, what favor or credit money represents has been lost. We’ve been conditioned to simply believing (Full Faith and Credit) that paper money has intrinsic value, when it simply doesn’t.

A ‘pacemaker’ for the brain is on the horizon to prevent people with Parkinson’s and epilepsy suffering from seizures and tremors.

The device is made up of two tiny array of electrodes which sit inside the skull, and link to a circuit board on the side of the head.

The ‘pacemaker’ records the normal electrical current of the brain continually and if it notices a change of rhythm immediately fires a stimulating charge to coax the pulse back to normal.

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