Fancy for a visit?
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On the degenerative disk disease and senescent cells from FightAging: “… It is just a pity that so few older people know this at the present time — the hundreds of millions worldwide who are suffering when perhaps they need not be…”
At this point, I suspect it will surprise no-one who follows the field to learn that the accumulation of senescent cells is a significant cause of degenerative disc disease. The evidence from a mouse study that is provided in the open access paper here doesn’t quite rise to establishing that claim, but it is compelling nonetheless. Given the role of cellular senescence in arthritis, a disease of localized chronic inflammation, it is logical to also expect a role in the degeneration of intervertebral discs, as this is also a condition of aging in which inflammation seems important.
Senescent cells, even while present in only comparatively small numbers, generate a potent mix of molecules that spurs chronic inflammation and is destructive of surrounding tissue structure. Fortunately early senolytic compounds, those shown to destroy a sizable fraction of senescent cells cells in animal studies, are cheap and readily available to anyone willing to try this self-experiment. It is just a pity that so few older people know this at the present time — the hundreds of millions worldwide who are suffering when perhaps they need not be.
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Topol is a dreamer. “One can imagine that AI will rescue medicine from all that ails it, including diagnostic inaccuracy,” he writes. (There are roughly 12 million misdiagnoses of serious illness in the United States every year, and medical error kills a quarter-million Americans annually.) But even Topol admits that this hope is far from being actualized. Indeed.
Cardiologist Eric Topol explores the benefits of artificial intelligence in medicine.
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A recent news topic that raised some eyebrows was the revelation that the human brain can literally reprogram itself. The brain is such a complex piece of hardware that there’s practically no way we’ll ever understand it without using a greater intelligence. This is one of the reasons why the emergence of artificial intelligence is so disruptive. Startups like Kernel are actually using AI to “read/write” long term memories directly from the brain. Amazing technological advances like these should adorn the front page of every news paper out there. Instead, we opt for mind-numbing “facts” like this:
As a nod to World Mental Health Day today, what we’d like to do is put together an exhaustive list of every single neurotech related company out there. To get this started, let’s turn towards an article published on the Crunchbase blog which lists 23 different neurotech companies (it’s actually 22 because one was an impostor). To that list, we then added 7 names from our own research. What we end up with is a list of 29 different neurotech companies (the companies we’ve already covered are linked to the relevant articles on this site below):
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Tourist spots in Paris, France… including Notre Dame. #NotreDame
A crisp, clear winter day over France provided the International Space Station a detailed view of the city of Paris. This image, rotated and cropped from the original, shows the recognizable street pattern of the city—and some of the world’s most notable landmarks—along the Seine River. One of the main avenues radiating like spokes from the Arc de Triomphe (image upper left) is the Avenue des Champs-Élysées running southeast to the Garden of Tuileries (Jardin des Tuileries).
The garden—recognizable by its light green color relative to the surrounding built materials—was originally commissioned by Catherine de Medici in 1559, and is now bounded by the Place de la Concorde to the northeast and the Louvre museum along the Seine River at the southeast end. Other, similarly colored parks and greenspaces are visible throughout the image. Farther south on the Seine is the Íle de la Cité, location of the famous Notre Dame cathedral. Perhaps most prominent is the characteristic €œA € profile of the Eiffel Tower west of the Jardin des Tuileries, highlighted by morning sunlight.
Astronaut photograph ISS016-E-21564 was acquired on January 7, 2008 with a Kodak 760C digital camera fitted with a 800 mm lens, and is provided by the ISS Crew Earth Observations experiment. The image was taken by the Expedition 16 crew, and is provided by the Image Science & Analysis Laboratory, Johnson Space Center. The image in this article has been cropped and enhanced to improve contrast. Lens artifacts have been removed. The International Space Station Program supports the laboratory to help astronauts take pictures of Earth that will be of the greatest value to scientists and the public, and to make those images freely available on the Internet. Additional images taken by astronauts and cosmonauts can be viewed at the NASA/JSC Gateway to Astronaut Photography of Earth. Caption by Cynthia A Evans, NASA-JSC.
Canada’s newly announced $5,000 incentive for electric vehicles is officially going into effect on May 1st next month and the federal government has released the list of eligible vehicles.
Tesla vehicles are officially ineligible for the incentive.
As we reported last month, the Canadian federal announced a new $5,000 incentive for electric cars with a $45,000 price limit, which virtually excluded Tesla vehicles.
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A new story on my latest article from #transhumanism critic Wesley J. Smith:
Oh my. Two of contemporary society’s most prominent anti-human utopian movements — radical environmentalism and materialistic transhumanism — appear on the verge of a bitter showdown.
When you think about it, that makes sense. Both movements see themselves as the future’s only hope. But their core purposes are incompatible. Radical environmentalists — “nature rights” activists, deep ecologists, Gaia theorists, and their fellow travelers that elevate nature above humanity — hijacked and refashioned traditional environmentalism into a mystical neo-earth religion that disdains homo Sapiens as a parasitical species afflicting the earth. These radicals hope to thwart our thriving off the land in order to “save the planet.” Indeed, I sometimes believe that if they could, they would forcibly revert our species to hunter/gatherers — without the hunting part.
In contrast, transhumanism denigrates both the natural world and normal human life as irredeemably limited, and worst of all, ending in death! They yearn to possess extraordinary capacities without having to work to attain them. Rather than pursue virtue, transhumanism expects to overcome human nature through applied technology. Indeed, movement prophets predict the coming of “Singularity” — a discreet moment in time when unstoppable cascading technology will enable transhumanists to “seize control of human evolution” and reengineer themselves into an immortal “post-human species.”
Bacterial cells that normally colonize our guts can distinguish themselves from other bacterial species using what’s traditionally considered their enemy—a virus. Researchers report April 16 in the journal Cell Reports that some bacteria use viruses that have infected them (i.e., phages) for self-recognition and thereby show greater fitness, repelling competitors that lack this adaptation.
This is the first evidence that cells can distinguish themselves from related competitors through the use of a virus. The implications are that we should re-evaluate the relationship between a virus and its cellular host in that there are sometimes benefits to having a viral infection.”
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