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In fact, according to IRENA’s new report, the most cost-effective strategy to achieve a “climate-safe future” — keeping global warming below 2 degrees Celsius (3.6 degrees Fahrenheit) — is an accelerated energy transition to renewables and energy efficiency coupled with electrification of key sectors like transportation.

This Renewable Energy Roadmap (REmap) scenario “would also save the global economy up to USD 160 trillion cumulatively over the next 30 years in avoided health costs, energy subsidies and climate damages.”

At the same time, IRENA reports, “every dollar spent on energy transition would pay off up to seven times.”

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Researchers have identified ketamine-induced brain-related changes that are responsible for maintaining the remission of behaviors related to depression in mice—findings that may help researchers develop interventions that promote lasting remission of depression in humans. The study, funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health, appears in the journal Science.

Major is one of the most common mental disorders in the United States, with approximately 17.3 million adults experienced a major depressive episode in 2017. However, many of the neural changes underlying the transitions between active depression, remission, and depression re-occurrence remain unknown. Ketamine, a fast-acting antidepressant which relieves depressive symptoms in hours instead of weeks or longer, provides an opportunity for researchers to investigate the short- and long-term biological changes underlying these transitions.

“Ketamine is a potentially transformative treatment for depression, but one of the major challenges associated with this drug is sustaining recovery after the ,” said study author Conor Liston, M.D., Ph.D., of Weill Cornell Medicine, New York City.

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In quantum physics, a vacuum is not empty, but rather steeped in tiny fluctuations of the electromagnetic field. Until recently it was impossible to study those vacuum fluctuations directly. Researchers at ETH Zurich have developed a method that allows them to characterize the fluctuations in detail.

Emptiness is not really empty – not according to the laws of , at any rate. The vacuum, in which classically there is supposed to be “nothing,” teems with so-called according to quantum mechanics. Those are small excursions of an electromagnetic field, for instance, that average out to zero over time but can deviate from it for a brief moment. Jérôme Faist, professor at the Institute for Quantum Electronics at ETH in Zurich, and his collaborators have now succeeded in characterizing those vacuum fluctuations directly for the first time.

“The vacuum fluctuations of the electromagnetic field have clearly visible consequences, and among other things, are responsible for the fact that an atom can spontaneously emit ,” explains Ileana-Cristina Benea-Chelmus, a recently graduated Ph.D. student in Faists laboratory and first author of the study recently published in the scientific journal Nature. “To measure them directly, however, seems impossible at first sight. Traditional detectors for light such as photodiodes are based on the principle that light particles – and hence energy – are absorbed by the detector. However, from the vacuum, which represents the lowest energy state of a physical system, no further energy can be extracted.”

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Guest writer Dr. Asimina Pantazi gives her impressions of the recent Berlin Undoing Aging Conference from the point of view of someone working in research.


As a millennial with limited orientation abilities but expertise with digital tools, I used Google Maps to find the venue, fearing that I would have no data and would get lost in Berlin, only to find out that I was only a couple of meters away from to the venue entrance.

The Undoing Aging 2019 conference took place on May 28–30 at Umspannwerk Alexanderplatz: a multi-level industrial setting, with metal stairs, funky lights, and a balcony overlooking the minimal conference hall. This gave me my first positive vibes.

Aubrey de Grey of the SENS Research Foundation and Michael Greve of the Forever Healthy Foundation organized a three-day event that focused on the cellular and molecular repair of age-related damage in order to medically control aging. The conference brought together a diverse audience from all corners of the world: scientists, doctors, students, biotechs, startups, pharma, investors, the media, government representatives, policy makers, and anti-aging research enthusiasts; many of them were Russians, and their country was impressively represented there!

Announces the publication of a new open-access quarterly report: AI for Drug Discovery, Biomarker Development and Advanced R&D Landscape Overview 2019/Q1. Except for providing the analysis of 350 investors, 50 corporations and 150 companies operating in the field, the main events that took place in the industry from January to March 2019 are covered. The report also features the list of 30 leading R&D centers that provide important researches in the segment.

Link to the Report: https://www.ai-pharma.dka.global/quarter-1-2019

#AI #artificialintelligence #drugdiscovery

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