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Laude × CSGE: Bill Joy — 50 Years of Advancements: Computing and Technology 1975–2025 (and beyond)

From the rise of numerical and symbolic computing to the future of AI, this talk traces five decades of breakthroughs and the challenges ahead.

Bill is the author of Berkeley UNIX, cofounder of Sun Microsystems, author of “Why the Future Doesn’t Need Us” (Wired 2000), ex-cleantech VC at Kleiner Perkins, investor in and unpaid advisor to Nodra. AI.

Talk Details.
50 Years of Advancements: Computing and Technology 1975–2025 (and beyond)

I came to UC Berkeley CS in 1975 as a graduate student expecting to do computer theory— Berkeley CS didn’t have a proper departmental computer, and I was tired of coding, having written a lot of numerical code for early supercomputers.

But it’s hard to make predictions, especially about the future. Berkeley soon had a Vax superminicomputer, I installed a port of UNIX and was upgrading the operating system, and the Internet and Microprocessor boom beckoned.

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South Carolina’s measles outbreak shows chilling effect of vaccine misinformation

But on a Monday afternoon in Boiling Springs, only one person showed up.

“It’s progress. That progress is slow,” Linda Bell, the state epidemiologist with the Department of Public Health, said during a recent press briefing. “We had hoped to see a more robust uptake than that in our mobile health units.”

As South Carolina tries to contain its measles outbreak, public health officials across the nation are concerned that the highly contagious virus is making a major comeback. The Centers for Disease Control and Prevention has tallied more than 1,700 measles cases and 45 outbreaks in 2025. The largest started in Texas, where hundreds of people were infected and two children died.

Robots combine AI learning and control theory to perform advanced movements

When it comes to training robots to perform agile, single-task motor skills, such as handstands or backflips, artificial intelligence methods can be very useful. But if you want to train your robot to perform multiple tasks—say, performing a backward flip into a handstand—things get a little more complicated.

“We often want to train our robots to learn new skills by compounding existing skills with one another,” said Ian Abraham, assistant professor of mechanical engineering. “Unfortunately, AI models trained to allow robots to perform complex skills across many tasks tend to have worse performance than training on an individual task.”

To solve for that, Abraham’s lab is using techniques from optimal control—that is, taking a mathematical approach to help robots perform movements in the most efficient and optimal way possible. In particular, they’re employing hybrid control theory, which involves deciding when an autonomous system should switch between control modes to solve a task. The research is published on the arXiv preprint server.

Artificial membranes mimic life-like dynamics through catalytic chemical reactions

Using catalytic chemistry, researchers at Institute of Science Tokyo have achieved dynamic control of artificial membranes, enabling life-like membrane behavior. The work is published in the Journal of the American Chemical Society.

By employing an artificial metalloenzyme that performs a ring-closing metathesis reaction, the team induced the disappearance of phase-separated domains as well as membrane division in artificial membranes, imitating the dynamic behavior of natural biological membranes. This transformative research marks a milestone in synthetic cell technologies, paving the way for innovative therapeutic breakthroughs.

How a key protein helps drive healthy longevity by maintaining a precise balance

Researchers at Bar-Ilan University have discovered how the longevity-associated protein Sirt6 orchestrates a delicate molecular balancing act that protects the body from age-related decline and disease. The new findings, just published in the Proceedings of the National Academy of Sciences, reveal how Sirt6 preserves health during aging and may pave the way for therapies that promote a longer, healthier life.

Sirt6, often described as a master regulator of aging, is known for its powerful protective effects against age-related diseases such as cancer, diabetes, inflammation, and frailty. Its impact closely resembles that of calorie restriction, a dietary regimen proven in animals to extend lifespan and enhance the body’s natural repair and healing mechanisms.

Calorie restriction—eating fewer calories without malnutrition—has long been known to improve health and extend lifespan. One of its key effects is to increase the body’s production of hydrogen sulfide (H2S), a tiny gas molecule that supports wound healing, heart health, and brain function. This new study found that as we age, H2S levels naturally decline, weakening these protective benefits.

Supercomputers decode the strange behavior of Enceladus’s plumes

Supercomputers are rewriting our understanding of Enceladus’ icy plumes and the mysterious ocean that may harbor life beneath them. Cutting-edge simulations show that Enceladus’ plumes are losing 20–40% less mass than earlier estimates suggested. The new models provide sharper insights into subsurface conditions that future landers may one day probe directly.

In the 17th century, astronomers Christiaan Huygens and Giovanni Cassini pointed some of the earliest telescopes at Saturn and made a surprising discovery. The bright structures around the planet were not solid extensions of the world itself, but separate rings formed from many thin, nested arcs.

Centuries later, NASA’s Cassini-Huygens (Cassini) mission carried that exploration into the space age. Starting in 2005, the spacecraft returned a flood of detailed images that reshaped scientists’ view of Saturn and its moons. One of the most dramatic findings came from Enceladus, a small icy moon where towering geysers shot material into space, creating a faint sub-ring around Saturn made of the ejected debris.

Historic Physics Breakthrough as Scientists Catch Dark Matter Behaving in Real Time | Highlights

The universe is mostly invisible. Dark matter, the mysterious substance making up 85% of cosmic mass, has been detected through a stunning gamma-ray signal. Join us as we break down the research by a University of Tokyo astrophysicist who believes he has caught WIMP particles destroying each other a finding that redefines our place in the cosmos.

#universe #space #darkmatter #wion.

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