Lifeboat Foundation

The loss of complete segments of the esophagus often results from treatments for esophageal cancer or congenital abnormalities, and current methods to re-establish continuity are inadequate. Now, working with a rat model, researchers have developed a promising reconstruction method based on the use of 3D-printed esophageal grafts. Their work is published in Tissue Engineering, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

Eun-Jae Chung, MD, PhD, Seoul National University Hospital, Korea, Jung-Woog Shin, PhD, Inje University, Korea, and colleagues present their research in an article titled “Tissue-Engineered Esophagus via Bioreactor Cultivation for Circumferential Esophageal Reconstruction”. The authors created a two-layered tubular scaffold with an electrospun nanofiber inner layer and 3D-printed strands in the outer layer. After seeding human mesenchymal stem cells on the inner layer, constructs were cultured in a bioreactor, and a new surgical technique was used for implantation, including the placement of a thyroid gland flap over the scaffold. Efficacy was compared with omentum-cultured scaffolding technology, and successful implantation and esophageal reconstruction were achieved based on several metrics.

Dr. Chung and colleagues from Korea present an exciting approach for esophageal repair using a combined 3D printing and bioreactor cultivation strategy. Critically, their work shows integration of the engineered esophageal tissue with host tissue, indicating a clinically viable strategy for circumferential esophageal reconstruction.”

Design of what could be a human colony in a narrow, artificial, domed canyon on Mars by LAVA architects.

When they aren’t investing in space shuttles and sprawling tech campuses, the super-rich are looking at mind-blowing methods to increase their lifespan.

Analysis by commercial finance experts ABC Finance has revealed some of the strangest and most extravagant approaches billionaires have turned to in their quest for immortality.

Credit where credit is due: Evolution has invented a galaxy of clever adaptations, from fish that swim up sea cucumber butts and eat their gonads, to parasites that mind-control their hosts in wildly complex ways. But it’s never dreamed up ion propulsion, a fantastical new way to power robots by accelerating ions instead of burning fuel or spinning rotors. The technology is in very early development, but it could lead to machines that fly like nothing that’s come before them.

You may have heard of ion propulsion in the context of spacecraft, but this application is a bit different. Most solar-powered ion spacecraft bombard xenon atoms with electrons, producing positively charged xenon ions that then rush toward a negatively charged grid, which accelerates the ions into space. The resulting thrust is piddling compared to traditional engines, and that’s OK—the spacecraft is floating through the vacuum of space, so the shower of ions accelerate the aircraft bit by bit.

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Coming into effect as early as 2021.

New formulations deliver nourishment on demand.

• By Jeff Carbeck on July 1, 2019

Every type of atom in the universe has a unique fingerprint: It only absorbs or emits light at the particular energies that match the allowed orbits of its electrons. That fingerprint enables scientists to identify an atom wherever it is found. A hydrogen atom in outer space absorbs light at the same energies as one on Earth.

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With that basic research, mankind found the first major clue to the origins of aging and death. They discovered that some cells in our bodies that may never die. These “immortal cells” and the philosophical shift in thinking they engendered, will likely change medicine as we know it.

Different African killifish species vary extensively in their lifespans—from just a few months to several years. Scientists from the Max Planck Institute for Biology of Ageing in Cologne investigated how different lifespans have evolved in nature and discovered a fundamental mechanism by which detrimental mutations accumulate in the genome causing fish to age fast and become short-lived. In humans, mutations accumulate mainly in the genes that are active in old age.