It took 12 years and at least $40 million to chart a region about 250 micrometers across—about the thickness of two strands of hair.
In mouse studies, a “methylation clock” on the ELOVL2 gene ticks toward impaired vision, but when gene expression was boosted, age-related visual function improved.
A lengthy-named gene called Elongation of Very Long Chain Fatty Acids Protein 2 or ELOVL2 is an established biomarker of age. In a new paper, published online January 14, 2020 in the journal Aging Cell, researchers at University of California San Diego School of Medicine say the gene appears to play a key role in age-associated functional and anatomical aging in vivo in mouse retinas, a finding that has direct relevance to age-related eye diseases.
Specifically, the research team, led by senior author Dorota Skowronska-Krawczyk, PhD, assistant professor in the Viterbi Family Department of Ophthalmology at UC San Diego Shiley Eye Institute, found that an age-related decrease in ELOVL2 gene expression was associated with increased DNA methylation of its promoter. Methylation is a simple biochemical process in which groups of carbon and hydrogen atoms are transferred from one substance to another. In the case of DNA, methylation of regulatory regions negatively impacts expression of the gene.
When researchers reversed hypermethylation in vivo, they boosted ELOVL2 expression and rescued age-related decline in visual function in mice. “These findings indicate that ELOVL2 actively regulates aging in mouse retina, provides a molecular link between polyunsaturated fatty acids elongation and visual functions, and suggests novel therapeutic strategies for treatment of age-related eye diseases,” wrote the authors.
UN Panel Sees Possible Role
Posted in futurism
United Nations experts said the Saudi Crown Prince Mohammed bin Salman was possibly involved in hacking the cellphone of Amazon.com Inc. Chief Executive Officer Jeff Bezos and have called for an investigation.
Quantum physics now states that matter is merely an illusion and that everything is energy at a different frequency in vibratory motion. This is something that science has only started to take seriously since the turn of the last century. However, this was something Hermes Trismegistus (the founder of the hermetic teachings) taught as one of the 7 principles of existence and recorded history of his teachings have dated back as far as the 1st century AD.
These teachings go further than modern science has the ability to quantify, but science is slowly catching up with many of the ideas shared. Here is a section on vibration which has been taken from the book The Kybalion is an introduction into the teachings of occult hermeticism and was derived from the ancient teachings of Hermes Trismegistus.
Nothing rests; everything moves; everything.
“A neuroscientist explains how our brains age and provides tips for aging with more vitality and happiness.”
https://greatergood.berkeley.edu/topic[/li
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About 13 years ago, I watched my very vital mother die a slow death from Lewy-Body dementia. For me, it was a wakeup call. If there were anything I could do to stay healthy myself—to avoid the slow decline of an aging brain—I wanted to do it. But what really helps us stay sharp longer? And how can we separate fad ideas from solid, evidence-based advice around aging?
Circa 2016
Taking vertical urban indoor farming efficiency to the next level, a new automated plant coming to Japan will be staffed entirely by robots and produce 30,000 heads of lettuce daily.
The so-called Vegetable Factory is a project of Spread, a Japanese company already operating vertical farms. Located in Kyoto, its small army of bots will various seed, water, trim and harvest the lettuce. Spread’s new automation technology will not only produce more lettuce, it will also reduce labor costs by 50%, cut energy use by 30%, and recycle 98% of water needed to grow the crops.
This was very real as a psychic I personally felt lots of lives lost.
It’s titled ‘Nightcrawlers.’
Circa 2018 I think the death toll is still too high to be measured still.
In an echo of Latin America’s “Dirty Wars,” tens of thousands of people have vanished in Mexico, leaving mothers behind to search for their corpses. This time the violence, linked to criminal networks, is more complex and more intractable.
The government said 61,637 people have disappeared since 1964, the vast majority since 2006, when then-president Felipe Calderón began cracking down on drug cartels.
Children were deprived of clean water and basic healthcare in armed conflicts, leading to preventable deaths, a study showed. Conflicts accounted for seven percent of all child deaths in Africa.