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The 2019 novel coronavirus or coronavirus disease (COVID-19) outbreak has threatened the entire world at present. Scientists are working day and night to understand the origin of COVID-19. You may have heard the news recently that the complete genome of COVID-19 has been published. How did scientists figure out the complete genome of COVID-19? In this article, I will explain how we can do this.

A genome is considered as all the genetic material, including all the genes of an organism. The genome contains all the information of an organism that is required to build and maintain it.

How can we read the information present in the genome? This is where sequencing comes into action. Assuming you have read my previous article on DNA analysis, you know that sequencing is used to determine the sequence of individual genes, full chromosomes or entire genomes of an organism.

Continue reading “Genome Assembly — The Holy Grail of Genome Analysis” | >

“The problem of plastic pollution is too large to simply throw worms and there is still a lot to do before we can parlay this work into making a meaningful contribution,” Cassone said. “Also, the larvae tend to eat less plastic with longer times on that type of diet. By understanding the process – why the breakdown of plastic occurs so rapidly in the waxworm—we can then begin to develop ways to really make a meaningful impact to plastic pollution.”

He continued: “Now that we know the microbiome plays a role, if we can better understand how the bacteria works together with the worm and what kind of conditions cause it to flourish, perhaps this information can be used to design better tools to eliminate plastics from our environment.”

Not all are convinced, however. Till Opatz, from the Department of Chemistry at the Johannes Gutenberg University, Germany, was critical of the initial findings that caterpillars digest plastic. At the time he and his colleagues said they disagreed with the methodology and conclusions reported, adding the study “does not provide sufficient proof” that G. mellonella can chemically destroy polyethylene.

Continue reading “Plastic-eating caterpillars have gut bacteria that can live on polyethylene for over a year” | >

Viruses and mobile genetic elements are molecular parasites or symbionts that coevolve with nearly all forms of cellular life. The route of virus replication and protein expression is determined by the viral genome type. Comparison of these routes led to the classification of viruses into seven “Baltimore classes” (BCs) that define the major features of virus reproduction. However, recent phylogenomic studies identified multiple evolutionary connections among viruses within each of the BCs as well as between different classes. Due to the modular organization of virus genomes, these relationships defy simple representation as lines of descent but rather form complex networks. Phylogenetic analyses of virus hallmark genes combined with analyses of gene-sharing networks show that replication modules of five BCs (three classes of RNA viruses and two classes of reverse-transcribing viruses) evolved from a common ancestor that encoded an RNA-directed RNA polymerase or a reverse transcriptase. Bona fide viruses evolved from this ancestor on multiple, independent occasions via the recruitment of distinct cellular proteins as capsid subunits and other structural components of virions. The single-stranded DNA (ssDNA) viruses are a polyphyletic class, with different groups evolving by recombination between rolling-circle-replicating plasmids, which contributed the replication protein, and positive-sense RNA viruses, which contributed the capsid protein. The double-stranded DNA (dsDNA) viruses are distributed among several large monophyletic groups and arose via the combination of distinct structural modules with equally diverse replication modules. Phylogenomic analyses reveal the finer structure of evolutionary connections among RNA viruses and reverse-transcribing viruses, ssDNA viruses, and large subsets of dsDNA viruses. Taken together, these analyses allow us to outline the global organization of the virus world. Here, we describe the key aspects of this organization and propose a comprehensive hierarchical taxonomy of viruses.

Met Basilisk zelfherstellende reparatiemortel herstelt u op eenvoudige wijze scheuren en verhelpt u lekkages in betonnen constructies. Traditionele reparatiemethoden moeten door het werken van de betonconstructie vaak na verloop van tijd worden herhaald. Door de zelfherstellende eigenschappen is dit bij Basilisk zelfherstellende reparatiemortel niet het geval: één reparatie volstaat. Ook als de constructie in de toekomst gaat werken.

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If shit ever hits the fan it is good to have a personal library downloaded on your phone. Because your phone be worthless but a digital library will not be.

If you are trying to find prepper and survival books, you’ve come to the right place. Below is a list of 667 of the best survival manuals, books, and survival guide PDF downloads. To download any of these titles, simply right-click on a file, and then select “Save As”.