2020, Antiviral Research
In the face of overwhelming demand and limited resources, health care would need to be rationed, with agonizing decisions.
As the coronavirus spreads through Colorado, local distilleries like Spirit Hound have begun making hand sanitizer.
NVIDIA is giving Coronavirus Researchers Access to Parabricks for 90 Days. Learn more.
Google has announced a new real-time transcription feature for its free Translate app for Android phones. An IOS version is planned for the future, the company says.
The feature will allow users to obtain instantaneous text translations of ongoing speeches, lectures or monologues into any of eight languages, including English.
Currently, Translate allows conversions of only relatively short snippets of speech.
In light of the ongoing shift toward renewable energy technologies and the growing number of Internet of Things (IoT) devices, researchers worldwide have been trying to develop batteries that can operate more efficiently and for longer periods of time. Lithium-ion batteries (LIBs) are currently the preferred energy-storage technology for portable electronics, as they contain organic electrolytes, which typically enable high operating voltages and energy densities.
Despite their widespread use, further increasing the performance of existing LIBs could have a significant impact on their safety. In fact, these batteries contain highly volatile and flammable organic carbonates, which, if ignited, can cause considerable damage.
In recent years, researchers have made significant efforts toward overcoming these safety issues, for instance, by using additional substances or by optimizing the materials separating battery components. While some of these strategies successfully reduced the risk of the battery catching fire, as long as LIBs are made with highly flammable electrolytes, accidents may still occur.
The neuromorphic approach is still in deep research, and is being investigated by Intel, IBM, HPE, MIT, Purdue, Stanford and others. It will likely be deployed in production solutions within the next three to five years. Like quantum computing, there is potential for a future solution than could be 1,000–10,000 times more efficient than the digital processing approach that is currently in vogue. But also like quantum, neuromorphic computing will require a lot of research to reach fruition. When it does, it will likely only be applied to a specific set of challenges. I will continue to watch with interest.
Analyst Karl Freund takes a look at Intel’s recent announcements in the realm of neuromorphic computing.
Circa 2014 Emerging respiratory coronaviruses such as the Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) and Middle East Respiratory Syndrome coronavirus (MERS-CoV) pose potential biological threats to humans. SARS and MERS are manifested as severe atypical pneumonia associated with high morbidity and mortality in humans. The majority of studies carried out in SARS-CoV-infected humans and animals attribute a dysregulated/exuberant innate response as a leading contributor to SARS-CoV-mediated pathology. A decade after the 2002–2003 SARS epidemic, we do not have any approved preventive or therapeutic agents available in case of re-emergence of SARS-CoV or other related viruses. A strong neutralizing antibody response generated against the spike (S) glycoprotein of SARS-CoV is completely protective in the susceptible host. However, neutralizing antibody titers and the memory B cell response are short-lived in SARS-recovered patients and the antibody will target primary homologous strain. Interestingly, the acute phase of SARS in humans is associated with a severe reduction in the number of T cells in the blood. Surprisingly, only a limited number of studies have explored the role of the T cell-mediated adaptive immune response in respiratory coronavirus pathogenesis. In this review, we discuss the role of anti-virus CD4 and CD8 T cells during respiratory coronavirus infections with a special emphasis on emerging coronaviruses.
Coronaviruses belong to the family coronaviridae and are enveloped, positive-sense, single stranded RNA viruses. The coronavirus genome is approximately 31 kb, making these viruses the largest known RNA viruses yet identified. Coronaviruses infect a variety of hosts including humans and several other vertebrates. Coronaviruses are associated with several respiratory and intestinal tract infections. Respiratory coronaviruses have long been recognized as significant pathogens in domestic and companion animals and as the cause of upper respiratory tract infections in humans. Thus, several human coronaviruses (HCoVs) are the etiological agents for mild respiratory illness, including the common cold and croup (e.g.: HCoV-229E, HCoV-OC43, HCoV-NL63 and HCoV-HKU) (3, 4). Human coronaviruses such as SARS-CoV and MERS-CoV are also associated with severe respiratory illness (5–9).
About 80,000 people worldwide have survived a Covid-19 infection. Their immune systems will have produced antibodies, which will help their bodies recognize and fight a repeat attack by the coronavirus. It’s a natural defense mechanism.
Aside from a Covid-19 vaccine, antibodies from recovered patients could provide a short-term “passive immunization” to the disease. A German immunologist saved thousands of lives with the method 100 years ago.