The origin of the universe started with the Big Bang, but how the supernova explosion ignited has long been a mystery – until now. In a new paper appearing today in Science Magazine, researchers detailed the mechanisms that could cause the explosion, which is key for the models that scientists use to understand the origin of the universe.
Authorities in China have approved a drug for the treatment of Alzheimer’s disease, the first new medicine with the potential to treat the cognitive disorder in 17 years.
The seaweed-based drug, called Oligomannate, can be used for the treatment of mild to moderate Alzheimer’s, according to a statement from China’s drug safety agency. The approval is conditional however, meaning that while it can go on sale during additional clinical trials, it will be strictly monitored and could be withdrawn should any safety issues arise.
In September, the team behind the new drug, led by Geng Meiyu at the Shanghai Institute of Materia Medica under the Chinese Academy of Sciences, said they were inspired to look into seaweed due to the relatively low incidence of Alzheimer’s among people who consume it regularly.
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Exactly when and where did life on Earth begin? Scientists have long thought that it emerged three billion years ago in the ocean — until astrobiologist Tara Djokic and her team made an unexpected discovery in the western Australian desert. Learn how an ancient rock found near a hot volcanic pool is shifting our understanding of the origin-of-life puzzle.
Continue reading “This ancient rock is changing our theory on the origin of life | Tara Djokic” »
Everis, an NTT DATA company and one of Spain’s largest managed service providers (MSP), had its computer systems encrypted today in a ransomware attack, just as it happened to Spain’s largest radio station Cadena SER (Sociedad Española de Radiodifusión).
While the ransomware attacks were not yet publicly acknowledged by the company, the ransom note left on Everis’ encrypted computers has already leaked and BleepingComputer can confirm that the MSP’s data was infected using the BitPaymer ransomware.
After months of warnings, the first successful attack using Microsoft’s BlueKeep vulnerability has arrived—but isn’t nearly as bad as it could have been.
From raindrops rolling off the waxy surface of a waterlily leaf, to the efficiency of desalination membranes, interactions between water molecules and water-repellent “hydrophobic” surfaces are all around us. The interplay becomes even more intriguing when a thin water layer becomes sandwiched between two hydrophobic surfaces, KAUST researchers have shown.
In the early 1980s, researchers first noted an unexpected effect when two hydrophobic surfaces were slowly brought together in water. “At some point, the two surfaces would suddenly jump into contact—like two magnets being brought together,” says Himanshu Mishra from KAUST’s Water Desalination and Reuse Center. Mishra’s lab investigates water at all length scales, from reducing water consumption in agriculture, to the properties of individual water molecules.
When the first smartphones arrived, few people understood how they would change our reality. Today, our internet-connected mobile device maps our travel, manages our finances, delivers our dinner, and connects us to every corner of human knowledge. In less than a generation, it has become almost an extension of our central nervous system — so indispensable that we can’t imagine leaving home without it to guide us.
We are about to embark on another journey even more important to every individual and to human society. We are entering the age of genomics, an amazing future that will dramatically improve the health outcomes of people across the planet. Soon, we won’t be able to imagine a time when we left home without knowledge of our genome to guide us.
Continue reading “How we Benefit from Getting our Genomes Sequenced” »
With ageing, intrinsic haematopoietic stem cell (HSC) activity decreases, resulting in impaired tissue homeostasis, reduced engraftment following transplantation and increased susceptibility to diseases. However, whether ageing also affects the HSC niche, and thereby impairs its capacity to support HSC function, is still widely debated. Here, by using in-vivo long-term label-retention assays we demonstrate that aged label-retaining HSCs, which are, in old mice, the most quiescent HSC subpopulation with the highest regenerative capacity and cellular polarity, reside predominantly in perisinusoidal niches. Furthermore, we demonstrate that sinusoidal niches are uniquely preserved in shape, morphology and number on ageing. Finally, we show that myeloablative chemotherapy can selectively disrupt aged sinusoidal niches in the long term, which is linked to the lack of recovery of endothelial Jag2 at sinusoids. Overall, our data characterize the functional alterations of the aged HSC niche and unveil that perisinusoidal niches are uniquely preserved and thereby protect HSCs from ageing.
