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Circa 2018

E-noses come in a variety of architectures, but most rely exclusively on chemical sensors, such as metal oxides or conducting polymers. The TruffleBot goes a step further: A 3.5-inch-by-2-inch circuit board that sits atop a Raspberry Pi contains eight pairs of sensors in four rows of two. Each sensor pair includes a chemical sensor to detect vapors and a mechanical sensor (a digital barometer) to measure air pressure and temperature.

Then comes the sniffing bit: Odor samples are pushed across these sensors by small air pumps that can be programmed to take up puffs of air in a pattern. “When animals want to smell something, they don’t just passively expose themselves to the chemical. They’re actively sniffing for it—sampling the air and moving around—so the signals that are being received are not static,” says Rosenstein.

In an analysis of nine odors, including those from cider vinegar, lime juice, beer, wine, and vodka (and using ambient air as a control), the team found that chemical sensors alone accurately identified an odor about 80 percent of the time. The addition of sniffing improved accuracy to 90 percent. Throw in the pressure and temperature readings and the e-nose recognized an odor 95 percent of the time.

Continue reading “Meet the E-Nose That Actually Sniffs” | >

A new weapon in the arsenal against the coronavirus may be sitting in your home entertainment console. A team led by physicist Chris Barty of the University of California, Irvine is researching the use of diodes from Blu-ray digital video disc devices as deep-ultraviolet laser photon sources to rapidly disinfect surfaces and the indoor air that swirls around us.

Barty, UC Irvine distinguished professor of physics & astronomy, said that such UV light sterilizers would be cheap compared to current medical- and scientific-grade systems and that it’d be possible to deploy them almost anywhere.

“If these sources are successful, I think you could build them into a mask and clean the air that’s coming in and out of you,” he said. “Or you could set these things up in the air circulation ducts of major buildings, and the airflow that goes through could be sterilized.”

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More than 100 teams around the world are racing to develop a coronavirus vaccine. Dr. Ofer Levy and a group of Harvard Medical School researchers are among them, but the vaccine they’re working on is a little different. It’s specifically designed for those most vulnerable to the disease: the elderly.

“Most vaccines are developed with a one-size-fits-all concept,” Levy told Business Insider. “Academic centers and companies typically develop a vaccine assuming that you will respond to the vaccine the same way, whether you’re a man or a woman, whether you’re young or elderly, whether you live in the US or Africa, whether you give the vaccine in the summer or winter, whether you give it in the morning or the evening.”

Vaccines generally aren’t as effective for the elderly. A Harvard lab is working on a COVID-19 vaccine that would be most effective for them.

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Henry Ford’s Model T was famously made partly from hemp bioplastic and powered by hemp biofuel. Now, with battery-powered vehicles starting to replace those that use combustion engines, it has been found that hemp batteries perform eight times better than lithium-ion. Is there anything that this criminally-underused plant can’t do?

The comparison has only been proven on a very small scale. (You weren’t expecting a Silicon Valley conglomerate to do something genuinely groundbreaking were you? They mainly just commercialise stuff that’s been invented or at least funded by the state.) But the results are extremely promising.

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Fasting-mimicking diets delay tumor progression and sensitize a wide range of tumors to chemotherapy, but their therapeutic potential in combination with non-cytotoxic compounds is poorly understood. Here we show that vitamin C anticancer activity is limited by the up-regulation of the stress-inducible protein heme-oxygenase-1. The fasting-mimicking diet selectivity reverses vitamin C-induced up-regulation of heme-oxygenase-1 and ferritin in KRAS-mutant cancer cells, consequently increasing reactive iron, oxygen species, and cell death; an effect further potentiated by chemotherapy. In support of a potential role of ferritin in colorectal cancer progression, an analysis of The Cancer Genome Atlas Database indicates that KRAS mutated colorectal cancer patients with low intratumor ferritin mRNA levels display longer 3- and 5-year overall survival. Collectively, our data indicate that the combination of a fasting-mimicking diet and vitamin C represents a promising low toxicity intervention to be tested in randomized clinical trials against colorectal cancer and possibly other KRAS mutated tumors.

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But Ben Shneiderman, a University of Maryland computer scientist who has for decades warned against blindly automating tasks with computers, thinks fully automated cars and the tech industry’s vision for a robotic future is misguided. Even dangerous. Robots should collaborate with humans, he believes, rather than replace them.

A computer scientist argues that the quest for fully automated robots is misguided, perhaps even dangerous. His decades of warnings are gaining more attention.

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Three critically ill patients at Baptist Hospital in Miami were the first in the U.S. to be successfully treated with stem cells.

The patients were suffering from acute respiratory distress syndrome, or ARDS, and doctors infused them intravenously with cells derived from the lining of umbilical cords.

These are called mesenchymal stem cells and within days after the infusion, the patients who needed 100% oxygen on ventilator support, saw their requirement slashed in half. This significant reduction was also accompanied by a drop in inflammatory markers, meaning that the harmful inflammation crippling the lungs was not only arrested but reversed, according to Baptist Health South

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Here’s a new chapter in the story of the miniaturization of machines: researchers in a laboratory in Singapore have shown that a single atom can function as either an engine or a fridge. Such a device could be engineered into future computers and fuel cells to control energy flows.” Think about how your computer or laptop has a lot of things inside it that heat up. Today you cool that with a fan that blows air. In nanomachines or quantum computers, small devices that do cooling could be something useful,” says Dario Poletti from the Singapore University of Technology and Design (SUTD).

This work gives new insight into the mechanics of such devices. The work is a collaboration involving researchers at the Centre for Quantum Technologies (CQT) and Department of Physics at the National University of Singapore (NUS), SUTD and at the University of Augsburg in Germany. The results were published in the peer-reviewed journal npj Quantum Information on 1 May.

Engines and refrigerators are both machines described by thermodynamics, a branch of science that tells us how energy moves within a system and how we can extract useful work. A classical engine turns energy into useful work. A refrigerator does work to transfer heat, reducing the local temperature. They are, in some sense, opposites.

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