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Dr. Adam Freund PhD., Calico Life Sciences, Discussing Google Quest to Solve Aging.

Ira Pastor, ideaXme life sciences ambassador interviews Dr Adam Freund, PhD, Principal Investigator at Calico Life Sciences (Calico). https://www.calicolabs.com

Ira Pastor comments:

Calico is a research and development focused biotechnology company founded and backed by Google / Alphabet with the goal of combating aging and associated age-related diseases.

Calico has a billion dollar partnership with the bio-pharma giant AbbVie, focused on aging and age-related diseases, such as neuro-degeneration and cancer. Calico also has partnerships with the University of Texas Southwestern Medical Center and 2M Companies (regarding drug development for neurodegenerative disorders), the Broad Institute of MIT and Harvard (to advance research on age-related diseases and therapeutics), and a partnership with the Buck Institute for Research on Aging.

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SOUTHLAKE, Texas, Oct. 22, 2020 /PRNewswire/ — Sabre Corporation (NASDAQ: SABR), the leading software and technology company that powers the global travel industry, today announced that Sabre and Google are developing an Artificial Intelligence (AI)-driven technology platform that is an industry first in travel. The technology, known as Sabre Travel AI™, is infused with Google’s state-of-the-art AI technology and advanced machine-learning capabilities that will help customers to deliver highly relevant and personalized content more quickly, deliver personalized content that better meets the demands of today’s traveler, and create expanded revenue and margin growth opportunities. The Company is integrating Sabre Travel AI into certain products in its existing portfolio, with plans to bring those to market in early 2021.

“Sabre Travel AI is a game-changer. We are proud to be working with Google to build technologies that will seek to re-define the way travel companies do business, and turn the insights derived from analyses into repeatable, scalable operations. The development of Sabre Travel AI marks a milestone in our technology transformation and a significant step toward achieving our 2025 vision of personalized retailing,” said Sundar Narasimhan, president of Sabre Labs. “With the creation of Sabre Travel AI, we are rebuilding our platform on cloud-native, data-driven technology that can be integrated into the existing and future products that Sabre offers. We are combining Google Cloud’s infrastructure, AI and machine-learning capabilities with Sabre’s deep travel domain knowledge to create, not next, but third-generation solutions that we believe are smarter, faster and more cost-effective – a first-of-its kind in travel.”

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Great new episode with the Smithsonian’s Jeremy R. Kinney. We discuss all aspects of how the seemingly mundane propeller drove the 20th Century’s revolution in aerospace and helped usher in an era of global warfare, travel, and trade.

Without the lowly propeller, global trade and commerce and freedom of movement as we knew it prior to Covid would have never had the opportunity to flourish. Special guest Jeremy R. Kinney, Chair of the Aeronautics Department at the Smithsonian Institution’s National Air and Space Museum in Washington, D.C., provides a fascinating narrative to how and why advances in aircraft propeller technology enabled aerospace to revolutionize global warfare, travel, and trade. Author of “Reinventing the Propeller,” Kinney and I discuss many underappreciated aspects of this aeronautical workhorse.

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A recent study from the University of Melbourne proposes a new theory for the origin of dark matter, helping experimentalists in Australia and abroad in the search for the mysterious new matter.

The work has been published in Physical Review Letters and describes how expanding bubbles in the early universe may be the key to understanding dark matter.

“Our proposed mechanism suggests that the dark matter abundance may have been determined in a cosmological phase transition,” said Dr. Michael Baker, a postdoctoral research fellow at the University of Melbourne and one of the authors.

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Can sub-zero stasis help humans escape death? In episode five of Hacking the Apocalypse, Claire Reilly goes inside a cryonics facility to investigate the experimental search for a second life.

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Nasa has provoked excitement across the world with the promise that it will reveal a “new discovery about the Moon” in a major announcement.

The space agency gave no details on what the announcement might be, apart from indicating that it “contributes to NASA’s efforts to learn about the Moon in support of deep space exploration” and had been made with Sofia, a converted Boeing 747 that works as a flying observatory.

But clues have begun to emerge about what the announcement could be about to reveal.

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Circa 2019

“Frustration” plus a pulse of laser light resulted in a stable “supercrystal” created by a team of researchers led by Penn State and Argonne National Laboratory, together with University of California, Berkeley, and two other national laboratories.

This is one of the first examples of a new state of matter with long-term stability transfigured by the energy from a sub-pico-second laser pulse. The team’s goal, supported by the Department of Energy, is to discover interesting states of matter with unusual properties that do not exist in equilibrium in nature.

“We are looking for hidden states of matter by taking the matter out of its comfortable state, which we call the ground state,” says the Penn State team leader Venkatraman Gopalan, professor of science. “We do this by exciting the electrons into a higher state using a photon, and then watching as the material falls back to its normal state. The idea is that in the excited state, or in a state it passes through for the blink of an eye on the way to the , we will find properties that we would desire to have, such as new forms of polar, magnetic and electronic states.”

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CJD happens when proteins called prions, which form incorrectly, find their way into the brain. Prions have the unfortunate, destructive ability to deform the proteins around them as well. As the prions gradually eat away at neurons, they create sponge-like holes in the brain. This leads to dementia, loss of bodily function, and eventually coma and death.

A new study — published last month in the journal Scientific Reports — looked at national data on people 50 years and older from Japan between the years 2005 and 2014 and found a gradual rise in the country’s CJD cases and deaths. The increase in both was most prominent among those older 70, but the Okayama University scientists behind the research saw a rise of CJD even after the data had been corrected for age.

“Given this trend in aging of population, the disease burden of CJD will continue to increase in severity,” the scientists wrote in their paper. “Our findings thus recommend that policymakers be aware of the importance of CJD and focus on preparing to address the increasing prevalence of dementia.”

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