Lifeboat Foundation

In the average human body, tens of billions of cells die everyday. It’s a natural process, important for keeping the body healthy. Now, for the first time, researchers at Yale School of Medicine have directly imaged the death of neurons in mice, as well as how the body clears them out afterwards.

Although it might seem like brain cells are things you’d definitely want to keep around, it’s better to get rid of the ones that aren’t working. After all, a build-up of dead cells can damage the nervous system and has been implicated in neurodegenerative diseases.

Continue reading “Yale captures first ever video of brain clearing out dead neurons” »

IBM on Monday announced it’s donating a series of open-source toolkits designed to help build trusted AI to a Linux Foundation project, the LF AI Foundation. As real-world AI deployments increase, IBM says the contributions can help ensure they’re fair, secure and trustworthy.

Whole genome duplication followed by massive gene loss has shaped many genomes, including the human genome. Why some gene duplicates are retained while most perish has puzzled scientists for decades.

A study, published today in Science, has found that gene retention depends on the degree of “functional and structural entanglement”, which measures interdependency between gene structure and function. In other words, while most duplicates either become obsolete or they evolve new roles, some are retained forever because, evolutionarily speaking, they’re simply stuck.

“When we scan genomes there are some gene pairs that remain from whole genome duplication events that occurred millions of years ago,” says Elena Kuzmin, a co-lead author of the study and former graduate student who trained with Charles Boone, professor of molecular genetics in the Donnelly Centre for Cellular and Biomolecular Research, at the University of Toronto, who co-led the study.

Ribonucleic acid, or RNA, is part of our genetic code and present in every cell of our body. The best known form of RNA is a single linear strand, of which the function is well known and characterized. But there is also another type of RNA, so-called “circular RNA,” or circRNA, which forms a continuous loop that makes it more stable and less vulnerable to degradation. CircRNAs accumulate in the brain with age. Still, the biological functions of most circRNAs are not known and are a riddle for the scientific community. Now scientists from the Max Planck Institute for Biology of Aging have come one step closer to answer the question what these mysterious circRNAs do: one of them contributes to the aging process in fruit flies.

Carina Weigelt and other researchers in the group led by Linda Partridge, Director at the Max Planck Institute for Biology of Aging, used fruit flies to investigate the role of the circRNAs in the aging process. “This is unique, because it is not very well understood what circRNAs do, especially not in an aging perspective. Nobody has looked at circRNAs in a longevity context before,” says Carina Weigelt who conducted the main part of the study. She continues: “Now we have identified a circRNA that can extend lifespan of fruit flies when we increase it, and it is regulated by insulin signaling.”

A type of anaerobic bacteria responsible for more than 50 percent of nitrogen loss from marine environments has been shown to use solid-state matter present outside their cells for respiration. The finding by KAUST researchers adds to knowledge of the global nitrogen cycle and has important energy-saving potential for wastewater treatment.

Living organisms use oxidation/reduction reactions to harvest the energy they need for survival. This involves the transfer of electrons from an electron donor to an electron acceptor with energy generation. In humans, electrons are released from the food we digest and accepted by soluble oxygen inside our cells. But in many bacteria, other strategies are used for oxidation/reduction, with different types of electron donors and acceptors.

Anammox are anaerobic bacteria found in oxygen-lacking marine and freshwater environments, such as sediments. They derive energy by using ammonium as their electron donor and intracellular soluble nitrite as the acceptor, with the release of nitrogen gas—or so scientists thought.

A team of French researchers have collaberated to create an advanced robotic “third arm”.

Read more

The wonder material graphene can take many forms for many different purposes, from transparent films that repel mosquitoes to crumpled balls that could boost the safety of batteries. One that has scientists particularly excited is nanoribbons for applications in energy storage and computing, but producing these ultra-thin strips of graphene has proven a difficult undertaking. Scientists are claiming a breakthrough in this area, devising a method that has enabled them to efficiently produce graphene nanoribbons directly on the surface of semiconductors for the first time.

As opposed to the sheets of carbon atoms arranged in honeycomb patterns that make up traditional graphene, graphene nanoribbons consist of thin strips just a handful of atoms wide. This material has great potential as a cheaper and smaller alternative to silicon transistors that would also run faster and use less power, or as electrodes for batteries that can charge in as little as five minutes.

“This is why many research groups around the world are focusing their efforts on graphene nanoribbons,” explains study author and chemist, Professor Konstantin Amsharov from Germany’s Martin Luther University of Halle-Wittenberg (MLU).

From an AI Chef to a Snoop Dog video ad, to digital people, here are 3 futuristic ways AI is taking brand voice to the next level.