An inexpensive assay based on the technique can provide yes or no answers in under an hour—perhaps even in the home soon.
Researchers at UT Southwestern Medical Center discovered that a protein called calcineurin plays a key role in blocking the ability of heart muscle to regenerate after the first week of life. The finding could be used to develop treatments that reverse this process, offering new strategies for repairing hearts damaged by heart attacks, high blood pressure, viruses and more, they said.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, at the end of 2019, and there are currently no specific antiviral treatments or vaccines available. SARS-CoV-2 has been shown to use the same cell entry receptor as SARS-CoV, angiotensin-converting enzyme 2 (ACE2). In this report, we generate a recombinant protein by connecting the extracellular domain of human ACE2 to the Fc region of the human immunoglobulin IgG1. A fusion protein containing an ACE2 mutant with low catalytic activity is also used in this study. The fusion proteins are then characterized. Both fusion proteins have a high binding affinity for the receptor-binding domains of SARS-CoV and SARS-CoV-2 and exhibit desirable pharmacological properties in mice. Moreover, the fusion proteins neutralize virus pseudotyped with SARS-CoV or SARS-CoV-2 spike proteins in vitro. As these fusion proteins exhibit cross-reactivity against coronaviruses, they have potential applications in the diagnosis, prophylaxis, and treatment of SARS-CoV-2.
SARS-CoV-2 uses ACE2 as the entry receptor. Here, the authors show that an ACE2-Ig fusion…
Robots could soon assist humans in a variety of fields, including in manufacturing and industrial settings. A robotic system that can automatically assemble customized products may be particularly desirable for manufacturers, as it could significantly decrease the time and effort necessary to produce a variety of products.
To work most effectively, such a robot should integrate an assembly planner, a component that plans the sequence of movements and actions that a robot should perform to manufacture a specific product. Developing an assembly planner that can rapidly plan the sequences of movements necessary to produce different customized products, however, has so far proved to be highly challenging.
Continue reading “An algorithm to enhance the robotic assembly of customized products” »
Children with autism were able to improve their social skills by using a smartphone app paired with Google Glass to help them understand the emotions conveyed in people’s facial expressions, according to a pilot study by researchers at the Stanford University School of Medicine.
Prior to participating in the study, Alex, 9, found it overwhelming to look people in the eye. Gentle encouragement from his mother, Donji Cullenbine, hadn’t helped. “I would smile and say things like, ‘You looked at me three times today!’ But it didn’t really move the bar,” she said. Using Google Glass transformed how Alex felt about looking at faces, Cullenbine said. “It was a game environment in which he wanted to win — he wanted to guess right.”
The therapy, described in findings published online Aug. 2 in npj Digital Medicine, uses a Stanford-designed app that provides real-time cues about other people’s facial expressions to a child wearing Google Glass. The device, which was linked with a smartphone through a local wireless network, consists of a glasses-like frame equipped with a camera to record the wearer’s field of view, as well as a small screen and a speaker to give the wearer visual and audio information. As the child interacts with others, the app identifies and names their emotions through the Google Glass speaker or screen. After one to three months of regular use, parents reported that children with autism made more eye contact and related better to others.
As cool as the Hoversurf Hoverbike is, the company is now working on another electric vertical takeoff and landing (eVTOL) air vehicle, the Hoversurf Formula. There are bigger ambitions for the latter.
Seriously now, how much fun would it be saying goodbye to colleagues as you make your way up the elevator to your eVTOL commuter, watching them go down road congestion hell while you go toward the sky? And as cool as a flying electric motorcycle is, HoverSurf is now going after the eVTOL challenge with a 4 to 6 passenger payload and 100 to 400 miles of range, or even further depending on its flight configuration.
Continue reading “After The Hoversurf Bike Comes The eVTOL Hoversurf Formula” »
TYLER, Texas (KETK) – Multiple news outlets are reporting that North Korean dictator Kim Jong-un has died.
TMZ was the first to report the news, writing, “North Korea’s Supreme Leader/dictator Kim Jong-un has reportedly died, or is on his death bed with no hope for recuperation — according to media outlets in China and Japan.”
Britain’s Express has also reported the news, citing “multiple sources coming out of North Korea and the Far East.”
Hubble Space Telescope’s iconic images and scientific breakthroughs have redefined our view of the Universe. To commemorate three decades of scientific discoveries, this image is one of the most photogenic examples of the many turbulent stellar nurseries the telescope has observed during its 30-year lifetime. The portrait features the giant nebula NGC 2014 and its neighbour NGC 2020 which together form part of a vast star-forming region in the Large Magellanic Cloud, a satellite galaxy of the Milky Way, approximately 163 000 light-years away. The image is nicknamed the “Cosmic Reef” because it resembles an undersea world.
On 24 April 1990 the Hubble Space Telescope was launched aboard the space shuttle Discovery, along with a five-astronaut crew. Deployed into low-Earth orbit a day later, the telescope has since opened a new eye onto the cosmos that has been transformative for our civilization.
Hubble is revolutionising modern astronomy not only for astronomers, but also by taking the public on a wondrous journey of exploration and discovery. Hubble’s seemingly never-ending, breathtaking celestial snapshots provide a visual shorthand for its exemplary scientific achievements. Unlike any other telescope before it, Hubble has made astronomy relevant, engaging, and accessible for people of all ages. The mission has yielded to date 1.4 million observations and provided data that astronomers around the world have used to write more than 17 000 peer-reviewed scientific publications, making it one of the most prolific space observatories in history. Its rich data archive alone will fuel future astronomy research for generations to come.
Google announced in late 2010 that for the past year, Californian drivers had been sharing the road with a secret self-driving car project. Many years and one death at the hands of rival Uber later, we can finally see 2009’s testing footage.
