Lifeboat Foundation

For the first time, a complete time-calibrated phylogeny for a large group of invertebrates is published for an entire continent.

In a recent research paper in the open-access, peer-reviewed academic journal ZooKeys, a German-Swedish team of scientists provide a diagrammatic hypothesis of the relationships and evolutionary history for all 496 European species of butterflies currently in existence. Their study provides an important tool for evolutionary and ecological research, meant for the use of insect and ecosystem conservation.

In order to analyse the ancestral relationships and history of evolutionary divergence of all European butterflies currently inhabiting the Old continent, the team led by Martin Wiemers—affiliated with both the Senckenberg German Entomological Institute and the Helmholtz Centre for Environmental Research—UFZ, mainly used molecular data from already published sources available from NCBI GenBank, but also contributed many new sequences, some from very local endemics for which no molecular data had previously been available.

In 2005, University of California, Berkeley, researchers made the surprising discovery that making conjoined twins out of young and old mice—such that they share blood and organs—can rejuvenate tissues and reverse the signs of aging in the old mice. The finding sparked a flurry of research into whether a youngster’s blood might contain special proteins or molecules that could serve as a “fountain of youth” for mice and humans alike.

But a new study by the same team shows that similar age-reversing effects can be achieved by simply diluting the blood plasma of old mice—no young blood needed.

In the study, the team found that replacing half of the blood plasma of old mice with a mixture of saline and albumin—where the albumin simply replaces protein that was lost when the original blood plasma was removed—has the same or stronger rejuvenation effects on the brain, liver and muscle than pairing with young mice or young blood exchange. Performing the same procedure on young mice had no detrimental effects on their health.

Why does this happen?

To put things as simply as possible, the root cause of all aging is a loss of energy on the cellular level, and there are basically two major theories for why this occurs. One says cellular energy decline is the result of accumulated cellular and mitochondrial damage. In other words, it’s the result of wear and tear on a cellular level. The other theory speculates that it is the result of genetic programming, with some genes getting overexpressed while others get underexpressed as we age.

These two theories of cellular energy decline aren’t in competition with one another. They just look at the problem from two different vantage points. The reality is these “causes” are interrelated. Gene overexpression and underexpression can cause cellular damage. Cellular damage can impair gene expressions.

How SpaceX is planning to go to MARS?

Watch yourself

#MarsExploration #SpaceExploration

Two studies point to a set of neurons that regulates states of torpor.

In July of 2015, the New Horizons spacecraft made history when it became the first robotic explorer to conduct a flyby of Pluto. This was followed by another first, when the NASA mission conducted the first flyby of a Kuiper Belt Object (KBO) on December 31st, 2018 – which has since been named Arrokoth. Now, on the edge of the Solar System, New Horizons is still yielding some groundbreaking views of the cosmos.

For example, we here on Earth are used to thinking that the positions of the stars are “fixed”. In a sense, they are, since their positions and motions are relatively uniform when seen from our perspective. But a recent experiment conducted by the New Horizons team shows how familiar stars like Proxima Centauri and Wolf 359 (two of the closest stars in our neighbors) look different when viewed from the edge of the Solar System.

Located in the constellation Leo, Wolf 359 is an M-type (red dwarf) star that is roughly 7.9 light-years from Earth. It can be found close to the same path the Sun follows through the sky (the ecliptic), but can only be seen with a telescope. And if you’re a Trekkie, you might recognize the name since it was where that major battle with the Borg took place (don’t act like you don’t know!)

A black hole, at least in our current understanding, is characterized by having “no hair,” that is, it is so simple that it can be completely described by just three parameters, its mass, its spin and its electric charge. Even though it may have formed out of a complex mix of matter and energy, all other details are lost when the black hole forms. Its powerful gravitational field creates a surrounding surface, a “horizon,” and anything that crosses that horizon (even light) cannot escape. Hence the singularity appears black, and any details about the infalling material are also lost and digested into the three knowable parameters.

Astronomers are able to measure the masses of black holes in a relatively straightforward way: watching how matter moves in their vicinity (including other black holes), affected by the gravitational field. The charges of black holes are thought to be insignificant since positive and negative infalling charges are typically comparable in number. The spins of black holes are more difficult to determine, and both rely on interpreting the X-ray emission from the hot inner edge of the accretion disk around the black hole. One method models the shape of the X-ray continuum, and it relies on good estimates of the mass, distance, and viewing angle. The other models the X-ray spectrum, including observed atomic emission lines that are often seen in reflection from the hot gas. It does not depend on knowing as many other parameters. The two methods have in general yielded comparable results.

CfA astronomer James Steiner and his colleagues reanalyzed seven sets of spectra obtained by the Rossi X-ray Timing Explorer of an outburst from a stellar-mass black hole in our galaxy called 4U1543-47. Previous attempts to estimate the spin of the object using the continuum method resulted in disagreements between papers that were considerably larger than the formal uncertainties (the papers assumed a mass of 9.4 solar-masses and a distance of 24.7 thousand light-years). Using careful refitting of the spectra and updated modeling algorithms, the scientists report a spin intermediate in size to the previous ones, moderate in magnitude, and established at a 90% confidence level. Since there have been only a few dozen well confirmed black hole spins measured to date, the new result is an important addition.

I remember I looked over a study from the Lancet. I questioned it. I have also read other studies, and I have questioned them. At least I know my questioning was within reason now. People can not spike studies and expect to get away with it, as the truth always comes out in the end.

Two major study retractions in one month have left researchers wondering if the peer review process is broken.

If there are only enough vaccines for a fraction of the world who will get them first?