Lifeboat Foundation

Two people with beta thalassaemia and one with sickle cell disease no longer require blood transfusions, which are normally used to treat severe forms of these inherited diseases, after their bone marrow stem cells were gene-edited with CRISPR.

Result of the ongoing trial, which is the first to use CRISPR to treat inherited genetic disorders, were announced today at a virtual meeting of the European Hematology Association.

This is really old news:

Two tried-and-true vaccines — a century-old inoculation against tuberculosis and a decades-old polio vaccine once given as a sugar cube — are being evaluated to see if they can offer limited protection against the coronavirus.

The old vaccines are oddities among the cutting-edge and targeted technologies being developed to combat the novel coronavirus. New vaccines aim to teach the body’s immune system to recognize and destroy the coronavirus, but scientists are only now beginning to test them in people. Vaccines developed against TB and polio have already been used in millions of people and could offer a low-risk way to rev up the body’s first line of defense — the innate immune system — against a broad array of pathogens, including the coronavirus.

Continue reading “Can old vaccines from science’s medicine cabinet ward off coronavirus?” »

Chinese company, Contemporary Amperex Technology Co. Ltd. (CATL), this week announced a new battery technology that could revolutionise the electric vehicle market.

Established in 2011 and headquartered in Ningde, eastern China, CATL employs more than 24,000 people and has grown to become the world’s largest maker of lithium batteries. Amid surging demand for electric vehicles, its revenue soared by 54% last year. China, as a whole, installed 62.2 GWh of battery storage capacity last year, according to the China Automotive Battery Industry Innovation Alliance, of which CATL supplied 31.5 GWh for a market share of nearly 51%.

In addition to domestic sales, CATL supplies a wide range of carmakers internationally – including Tesla, BMW, Toyota, Honda, and Volkswagen. While sales have slumped more recently, due to the COVID-19 pandemic, CATL and its clients are expecting demand to return in 2021.

Rational design of compounds with specific properties requires understanding and fast evaluation of molecular properties throughout chemical compound space — the huge set of all potentially stable molecules. Recent advances in combining quantum-mechanical calculations with machine learning provide powerful tools for exploring wide swathes of chemical compound space. We present our perspective on this exciting and quickly developing field by discussing key advances in the development and applications of quantum-mechanics-based machine-learning methods to diverse compounds and properties, and outlining the challenges ahead. We argue that significant progress in the exploration and understanding of chemical compound space can be made through a systematic combination of rigorous physical theories, comprehensive synthetic data sets of microscopic and macroscopic properties, and modern machine-learning methods that account for physical and chemical knowledge.

An international collaboration of scientists has recorded the most accurate confirmation to date for one of the cornerstones of Einstein’s theory of general relativity, ‘the universality of free fall.’

The new research shows that the theory holds for strongly self-gravitating objects such as neutron stars. Using a radio telescope, scientists can very accurately observe the signal produced by pulsars, a type of neutron star and test the validity of Einstein’s theory of gravity for these extreme objects. In particular, the team analyzed the signals from a pulsar named ‘PSR J0337+1715’ recorded by the large radio telescope of Nançay, located in the heart of Sologne (France).

The universality of free fall principle states that two bodies dropped in a gravitational field undergo the very same acceleration independently of their composition. This was first demonstrated by Galileo who famously would have dropped objects of different masses from the top of Pisa’s tower to verify that they both reach the ground simultaneously.

Please listen to the second episode of my new Cosmic Controversy Podcast. This week’s guest is planetary scientist Stephen Kane at the University of California, Riverside, who discusses why Venus is so haunting and beguiling all at once.

In this wide-ranging interview, planetary scientist Stephen Kane of the University of California, Riverside, delves into the mysteries of our neighbor planet Venus. We discuss how Venus went wrong and why understanding its evolution is so important in characterizing extrasolar planetary systems like our own.

GlaxoSmithKline has penned deals offering its pandemic vaccine adjuvant to several developers of COVID-19 shots. And it needs to amp up supply for those companies to make enough doses of their final products.

Now, the British pharma said it will make 1 billion doses of the adjuvant, dubbed AS03, in 2021 for use in multiple COVID-19 vaccine candidates.

Theoretically, the adjuvant can increase the body’s immune response to the vaccine component it’s paired with, reducing the amount of vaccine needed for each shot and allowing manufacturers to make more doses.

Sleek — but familiar.

The SolarStratos will gain its power from 240 square feet of solar panels on its wings.